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Dr. Bruno Luca

Biologist, Researcher
Bruno Luca
Research line: Research Line of Glaucoma and anterior segment with ocular annexes
Research unit: RU Research laboratory

Basic research activity at IRCCS Fondazione G.B. Bietti, Via Livenza 3 and Via di Santo Stefano Rotondo 6, Presidio Ospedaliero Britannico, Rome

Scientific publications:

 

  • 2024 – Degree in Biological Sciences, Roma Tre University

  • 2014 – Training in Flow Cytometry and Cell Sorter, IRCCS Fondazione S. Lucia – CERC, Rome, Italy

  • 2013 – Training in Biobanking, Biobank IRCCS San Raffaele, Rome, Italy

  • 2012 – Training in Clinical Diagnostics, Diagnostic Center – IRCCS San Raffaele, Rome, Italy

  • 1994 – Laboratory Technician in Biochemistry (DM n. 264, 27.04.1995)

  • 1991 – High School Diploma in Clinical Chemical Health Technology – Specialization as Senior Technician in Clinical Chemical Health

  • Jan 2018 – Present – Permanent contract at IRCCS – Fondazione G.B. Bietti, Research Laboratory in biochemistry, molecular and cellular biology applied to ophthalmological sciences (ISO 9001:2005) – Trial MGT-RPGR-021/22 – Clinical Analysis Laboratory (since March 2022)
  • May 2015 – 2018 – Research Contractor at IRCCS – Fondazione G.B. Bietti, Basic Science Research Laboratory
  • Jan 2014 – Jan 2015 – Research Contractor at IRCCS – Fondazione S. Lucia E.B.R.I., Neuroimmunology Laboratory
  • Oct 2012 – Apr 2015 – Research Contractor at IRCCS San Raffaele, Clinical Diagnostic Center and specialized operator at Biobank
  • Jun 2005 – Apr 2015 – Research Contractor at Fondazione Tor Vergata, Quality Control Laboratory
  • Dec 2007 – Sept 2012 – Permanent contract at Sigma-Tau S.p.A., Molecular Neurobiology Laboratory
  • Jan 2000 – Nov 2007 – Permanent contract at Kenton Srl (Biotechnology Company), Molecular Biology Laboratory
  • Sept 1997 – Dec 1999 – Permanent contract at Fondazione Santa Lucia
  • Dec 1996 – Aug 1997 – Internship at IRBM – Istituto di Ricerca Bio-Molecolare “Angeletti”
  • Oct 1994 – Jan 1995 – Internship at Italian Red Cross – Transfusion Center Laboratory
  • Jan 1994 – Sept 1994 – Internship at Pizzo e Salvatori – Clinical Chemistry Laboratory

  • Coordination and management of laboratory support activities (documentation and procedures: biological waste management, budget and order management, logistics management)

  • Quality Manager (RSGQ) for the Scientific Research Laboratory

  • Co-author of SOP procedures and Operating Instructions for ISO 9001 certification, Bureau Veritas – obtained on 25.10.2019, renewed annually

  • Experimental participation in the Italian National Antarctic Research Program (PNRA), D.D. 1314 of 25/05/2018 PNRA18_00341 – F – Coordinator: Alessandra Micera
    Project: “Evolution of the tear film in the Antarctic region: biostrumental, biochemical and behavioral mediators”

  • Technical operator for gene therapy clinical trials: MGT-RPGR-021 and MGT-RPGR-022 (Principal Investigator: Dr. L. Ziccardi)
  • Identification of a human immunodominant B-cell epitope within the GRA1 antigen of Toxoplasma gondii by phage display of cDNA libraries. Beghetto E, Pucci A, Minenkova O, Spadoni A, Bruno L, Buffolano W, Soldati D, Felici F, Gargano N. Int J Parasitol. 2001 Dec;31(14):1659-68. doi: 10.1016/s0020-7519(01)00288-0. 

 

  • Chimeric antigens of Toxoplasma gondii: toward standardization of toxoplasmosis serodiagnosis using recombinant products. Beghetto E, Spadoni A, Bruno L, Buffolano W, Gargano N. J Clin Microbiol. 2006 Jun;44(6):2133-40. doi: 10.1128/JCM.00237-06. 

 

  • Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution. Carnevale C, Manni G, Roberti G, Micera A, Bruno L, Cacciamani A, Altafini R, Quaranta L, Agnifili L, Tanga L, Riva I, Oddone F. PLoS One. 2019 Nov 14;14(11):e0224982. doi: 10.1371/journal.pone.0224982. eCollection 2019. 

 

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  • Alzheimer’s Disease and Retinal Degeneration: A Glimpse at Essential Trace Metals in Ocular Fluids and Tissues. Micera A, Bruno L, Cacciamani A, Rongioletti M, Squitti R. Curr Alzheimer Res. 2019;16(12):1073-1083. doi: 10.2174/1567205016666191023114015 

 

  • NGF in Inflammatory and Neurodegenerative Diseases of the Eye: New Findings Supporting Neuroprotection and Proper Tissue Remodeling in Vitreoretinal Disorders. Esposito G, Balzamino B O, Bruno L, Cacciamani A, Micera A. Adv Exp Med Biol. 2021:1331:265-273.doi: 10.1007/978-3-030-74046-7_18.  

 

  • Phacoemulsification and nucleic acid-enriched aerosol: considerations from an eye model of cataract simulation. Cacciamani A, Scarinci F, Bruno L, Balzamino B O, Cafiero C, Re A, Cosimi P, Ripnadelli G, Micera A. Graefes Arch Clin Exp Ophthalmol. 2021 Dec;259(12):3721-3727. doi: 10.1007/s00417-021-05350-6. Epub 2021 Aug 26 

 

  • Short-Term In Vitro ROS Detection and Oxidative Stress Regulators in Epiretinal Membranes and Vitreous from Idiopathic Vitreoretinal Diseases. Balzamino B O, Dinice L, Cacciamani A, Re A, Scarinci F, Bruno L, Cosimi P, Micera A. Biomed Res Int. 2022 Dec 16:2022:7497816.doi: 10.1155/2022/7497816. eCollection 2022. 

 

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