Dr. Micera Alessandra, PhD (Head of Operative Unit)
Alessandra Micera (12-01-1969) graduated in Biology in 1993 (La Sapienza University in Rome), with an experimental thesis carried out in the Neurobiology Institute (Prof. Rita Levi-Montalcini, CNR, Rome). She has carried out research at the MRC Laboratory of Molecular Biology (Cambridge, UK; 1994-1995) and in 2007 she earned a PhD in Immunopharmacology from the Hadassah Medical School-Hebrew University (School of Pharmacy, Faculty of Medicine, Jerusalem Israel). She is an on-demand reviewer for several international journals (10) and grant applications, member of Editorial board (2) and was an invited guest editor for special issue (1). She is principal investigator on a grant from Regione Lazio (2015) and was principal investigator/partner (1/2) of previous national founded projects in the area of Neurobiology and Ophthalmology. As Molecular and Cellular Biologist, she has a well-documented expertise in the Basic and translational research, with a multidisciplinary approach centered on the real needs of the basic and translational research Laboratory of Ophthalmology and the cross-talk between Clinique and Laboratory (experimental diagnostic). She collaborates with the University Campus Bio-Medico, carrying out integrated teaching (Human Physiology) and tutoring (thesis in Ophthalmology) activities at the Faculty of Medicine and with the Catholic University performing seminars (Faculty of Medicine). She was scientific responsible/invited speaker (6/3) for workshop with ECM. She is currently responsible of the U.O.S.D Research Laboratories of the IRCCS-GB Bietti Eye Foundation, including a main Laboratory (since 09/2015) and a small laboratory at the University Campus Bio-Medico focused on the study of Ocular Surface (since 2006).
Main research interests
- analysis of candidate biomarkers for early diagnosis and monitoring of therapy in some invalidating ocular diseases.
- the complex network between cells and mediators during innate/adaptive response, inflammation and tissue remodeling
- Nerve Growth Factor (NGF) contribution in chronic allergic inflammatory disorders associated with tissue remodelling and fibrosis, with a particular interest for Ocular surface diseases.
- developing of in vivo/in vitro (1D/3D) models
- support to the ocular diagnostics through the development of Standardized Operating Procedures and usage of laboratory tools (protein microarrays, HPLC, molecular analysis and static/dynamic cytometry).
- Design and development of not invasive alternative tools/strategies for sampling and on-site analysis for ocular surface and posterior segment (from ocular fluids to bioptic tissues).
She is co-author of 85 papers (total Impact Factor: 258.445); 95 Abstracts (oral or poster communications, invited lectures, some peer-reviewed on ISI Web of Knowledge) at International (72) and National (23) congrex presentations); 9 chapters in books and popular magazines; 1 Italian Patent (n. 140376; 2013) and 1 International Patent Pending (PCT/IB2016/051474; 04/2016).