Per la ricerca Archivi - Fondazione G.B. Bietti

Come usiamo i fondi

La Fondazione Bietti è stata riconosciuta istituto di ricovero e cura a carattere scientifico con decreto ministeriale del 15 febbraio 2005, successivamente confermato tempo per tempo mediante stesso provvedimento. Per l’attività di ricerca scientifica la Fondazione riceve contributi sia da enti pubblici che privati.

5×1000

In ottemperanza all’art.16 comma 5 del DPCM 23/07/2020 l’ IRCCS Fondazione G.B. Bietti per lo studio e la Ricerca in Oftalmologia ETS (C.F. 07864670588) pubblica l’ammontare dei contributi del 5 per mille incassati nel corso del 2020.

Ogni anno, il Direttore Scientifico comunica al Comitato Scientifico la disponibilità del contributo del 5×1000 e avvia una procedura di consultazione tra i ricercatori delle Unità di Ricerca, invitandoli a manifestare interesse per l’accesso a tali risorse al fine di sostenere nuovi progetti di ricerca. I responsabili delle linee di ricerca interessati devono presentare le loro proposte progettuali al Direttore Scientifico. Le proposte raccolte vengono sottoposte alla valutazione del Comitato Scientifico. Al termine della valutazione, il Direttore Scientifico approva la graduatoria dei progetti e assegna le risorse disponibili in base alla posizione in graduatoria. Vengono inoltre identificati i progetti ammissibili ma non finanziabili, che potranno essere finanziati successivamente, nel rispetto dell’ordine di graduatoria, qualora si rendano disponibili ulteriori risorse finanziarie derivanti da altre entrate.

Contributi in conto esercizio

Attualmente, i contributi di natura pubblica sono erogati dal Ministero della Salute, sotto forma di contributo annuale in conto esercizio per la ricerca corrente.

Fondazione Roma, socio di maggioranza della Fondazione Bietti, eroga un contributo annuale in conto esercizio a sostegno delle attività di ricerca (90% del contributo) e a copertura dei costi di struttura (10%).

Grazie ai contributi di cui sopra, la Fondazione copre i costi delle attività correnti legati alla ricerca, quali i costi del personale, acquisto di beni e servizi, noleggi e leasing, ecc.

Studi sponsorizzati

La Fondazione, in coerenza con la propria mission, svolge attività di sperimentazione clinica attraverso la stipula di specifici contratti con soggetti privati (Sponsor), che sotto la propria responsabilità, commissionano e/o finanziano una sperimentazione clinica.

Studi spontanei con finanziatore esterno

La Fondazione, stipula accordi con aziende del settore, interessate alla ricerca e sviluppo in ambito oftalmologico, per studi spontanei che prevedano finanziamenti a copertura dei costi del progetto.

Contributi in conto capitale

La Fondazione può usufruire di contributi in conto capitale, finalizzati all’acquisto di strumentazioni di ultima generazione, a scopi scientifici.

I contributi in conto capitale per l’acquisto di strumentazioni scientifiche possono essere erogati dal Ministero della Salute, mediante partecipazione ad un bando; se vincitori, il Ministero finanzia in tutto o in parte l’acquisto della strumentazione.

Anche Fondazione Roma, negli anni, ha contribuito a finanziare acquisti, fino al 90% del costo, di importanti strumentazioni scientifiche.

La Fondazione Roma ha contribuito (fino al 90% del costo) a finanziare le seguenti strumentazioni (di seguito le più significative):

Microscopio operatorio Leica: costo complessivo € 182.268,00. Contributo FR: € 164.041,20
High Performance Liquid Chromatography (HPLC): costo complessivo € 181.687,98. Contributo FR € 163.519,57
Strumentazione “Tomografo/topografo/pupillometro SM39”: costo complessivo di € 73.200,00. Contributo FR: € 63.000,00
Strumentazione EIBOS 2: costo complessivo € 44.442,16. Contributo FR € 30.964,00
Laser Lightlas SLT Deux: costo di € 50.532,85. Contributo FR € 45.119,57

Conto Capitale Ministero Salute

CC-2015-2365319

Piattaforma diagnostica digitale per la valutazione non invasiva in multifluorescenza integrata all’analisi dei flussi vascolari per le neoplasie oculari, importo finanziato € 195.200,00, con i quali è stata acquistata la seguente strumentazione:

Sistema Heidelberg SPECTRALIS COMBO2 MC OCTA con i seguenti moduli:

1. Modulo SLO per IR-AF-FA-NIR-ICG-MULTICOLOR;
2. Modulo OCT 85000 Hz. ad alta definizione;
3. MODULO OCTA per Angio OCT Full Spectrum Amplitude Decorrelation (FSADA).

CC-2016-2365451

Ottimizzazione dei risultati morfologici e funzionali della chirurgia vitreo-retinica: diagnosi precoce, valutazione della progressione del danno e ridotto traumatismo nella chirurgia vitreo-retinica, importo finanziato € 210.828,20, con i quali è stata acquistata la seguente strumentazione:

NGENUITY 3D VISION SISTEM
CIRRUS HD-OCT 5000
Microperimetro MP3 Nidek
Oftalmoscopio indiretto senza fili Vantage Plus a Led con batteria Slimline a litio e ricaricatore

CC-2019- 2366541

Trattamento con laser sottosoglia micropulsato PASCAL SYNTHESIS 577™ nelle patologie retiniche ad alto impatto sociale: valutazione della sua applicazione clinica attraverso lo studio funzionale della retina e della conduzione nervosa lungo le vie ottiche tramite apparato RETIMAX ADVANCED PLUS, importo finanziato € 167.506,00, con i quali è stata acquistata la seguente strumentazione:

Laser retinico PASCAL Synthesis 577
RETIMAX ADVANCED PLUS

CC-2022-23682590

Sistema Funzionale per lo studio della correlazione fenotipo-genotipo delle patologie oculari a carattere ereditario mediante imaging ad alta risoluzione, importo finanziato € 512.998,00, con i quali è stata acquistata la seguente strumentazione:

OPTOS SILVERSTONE SS OCT
MICROSCOPIO SPECULARE KONAN CELLCHEK C
CFX OPUS 96 DX REAL TIME PCR SYSTEM BIORAD

Pubblicazioni 2022

UR GLACOMA

1) In Vivo Confocal Microscopy of the Corneal Sub-Basal Nerve plexus in Medically Controlled Glaucoma.

Agnifili L., Brescia L., Villani E., D’Onofrio G., Figus M., Oddone F., Nucci P., Mastropasqua R.

Microsc Microanal. PMID: 34991750 DOI: 10.1017/S1431927621013969

2) Introductory remarks.

Ascenzi P., Bellelli A., Coletta M.

Mol Aspects Med. PMID 35022137. https://doi.org/10.1016/j.mam.2022.101065

3) Cochrane Corner: evidence on the management of primary angle closure glaucoma

Michelessi M., Azuara-Blanco A., Virgili G.

Eye (Lond). PMID 35031705 . DOI: 10.1038/s41433-021-01848-9

4) Sustained release glaucoma therapies: Novel modalities for overcoming key treatment barriers associated with topical medications.

Belamkar A., Harris A., Zukerman R., Siesky B., Oddone F., Verticchio Vercellin A., Ciulla TA.

Ann Med. 2022 ;54(1):343-358.doi: 10.1080/07853890.2021.1955146.

5) Glaucoma Treatment Outcomes in Open-Angle Glaucoma Patients of African Descent.

Siesky B., Harris A., Belamkar A., Zukerman R., Horn A., Vercellin AV., Mendoza KAV., Sidoti PA, Oddone F.

J Glaucoma. 2022 Mar 29. doi: 10.1097/IJG.0000000000002027. Online ahead of print.

6) Choroidal Thickness and Primary Open-Angle Glaucoma-A Narrative Review.

Alice Verticchio Vercellin, Alon Harris, Ari M. Stoner, Francesco Oddone, Kristen Ann Mendoza and Brent Siesky

J Clin Med. 2022 feb 23;11(5):1209. Doi: 10.3390/jcm11051209

7) Neuroprotective Effect of Carnosine Is Mediated by Insulin-Degrading Enzyme”.

Distefano A., Caruso G., Oliveri V., Bellia F., Sbardella D., Zingale GA, Caraci F., Grasso G.

ACS Chem Neurosci. 2022 May 18;13(10):1588-1593.doi: 10.1021/acschemneuro.2c00201. Epub 2022 Apr 26.

8) “Switching to Preservative-Free Tafluprost/Timolol Fixed-Dose Combination in the Treatment of Open-Angle Glaucoma or Ocular Hypertension: Subanalysis of Data from the VISIONARY Study According to Baseline Monotherapy Treatment”.

Oddone F., Kirwan J., Lopez-Lopez F., Zimina M., Fassari C., Holló G.; VISIONARY Study Group.

Adv Ther. 2022 May 7.doi: 10.1007/s12325-022-02166-6. Online ahead of print.

9) “Hydroxylamine-induced oxidation of ferrous nitrobindins”.

De Simone G., Tundo GR (problema doppia affiliazione), Coletta A., Coletta M, Ascenzi P.

J Biol Inorg Chem. 2022 May 11.doi: 10.1007/s00775-022-01940-9. Online ahead of print.

10) “Asian Race and Primary Open-Angle Glaucoma: Where Do We Stand?”

Belamkar A., Harris A., Oddone F., Verticchio Vercellin A., Fabczak-Kubicka A., Siesky B.

J Clin Med. 2022 Apr 28;11(9):2486. doi: 10.3390/jcm11092486.

11) “Silybins are stereospecific regulators of the 20S proteasome”.

Persico M., García-Viñuales S., Santoro AM, Lanza V., Tundo GR, Sbardella D., Coletta M., Romanucci V., Zarrelli A., Di Fabio G., Fattorusso C., Milardi D.

Bioorg Med Chem. 2022 Jul 15;66:116813.doi: 10.1016/j.bmc.2022.116813. Epub 2022 May 10.

12) “A comparison of country-level data from the VISIONARY study examining treatment outcomes with preservative-free tafluprost/timolol fixed-dose combination therapy”.

Holló G., Kirwan J., Lopez-Lopez F., Zimina M., Fassari C., Oddone F.; VISIONARY study group.

Curr Med Res Opin. 2022 Jun 9;1-13.doi: 10.1080/03007995.2022.2083324. Online ahead of print

13) “The current use of glaucoma virtual clinics in Europe.”

Azzopardi M., Prokosch-Willing V., Michelessi M., Fea AM, Oddone F., Mercieca K.

Eye (Lond). 2022 Jun 11;1-7.doi: 10.1038/s41433-022-02111-5. Online ahead of print.

14) Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution”

PersicoM., Santoro A. M., D’Urso A., MilardiD., PurrelloR., Cunsolo A., Gobbo M., Fattorusso R., Diana D., Stefanelli M., Sbardella D., Coletta M., Fattorusso C.

Biomolecules. 2022 May 24;12(6):741. doi: 10.3390/biom12060741.

15) “Dissociation of the proximal His-Fe bond upon NO binding to ferrous zebrafish nitrobindin”

De Simone G., Fattibene P. ,Sebastiani F., Smulevich G., Coletta M., Ascenzi P.

J Inorg Biochem.2022 Nov;236:111962. doi: 10.1016/j.jinorgbio.2022.111962. Epub 2022 Aug 17.

16) “Nitrosylation of ferric zebrafish nitrobindin: A spectroscopic, kinetic, and thermodynamic study”

De Simone G., Sebastiani F., Smulevich G., Coletta M., Ascenzi P.

J Inorg Biochem. 2022 Sep 15;237:111996. doi: 10.1016/j.jinorgbio.2022.111996. Online ahead of print.

17) “Italian Candidates for the XEN Implant: An Overview from the Glaucoma Treatment Registry (XEN-GTR)”

Posarelli C., Figus M., Roberti G., Giammaria S., Ghirelli G., Quercioli P., Micelli Ferrari, Pace V., Mastropasqua L., Agnifili L., Sacchi M., Scuderi G. , Perdicchi A., Altafini R., Uva M., D’Andrea D., Covello G., Maglionico M. N., Fea A. M., Carnevale C., Oddone F.

J Clin Med. 2022 Sep 9;11(18):5320. doi: 10.3390/jcm11185320.

18) “Glaucoma Progression Diagnosis: The Agreement between Clinical Judgment and Statistical Software”

Roberti G., Michelessi M., Tanga L., Belfonte L., Del Grande L. M., Bruno M., Oddone F.

Clin. Med. 2022, 11(19), 5508; https://doi.org/10.3390/jcm11195508

19) “The Balancing of Peroxynitrite Detoxification between Ferric Heme-Proteins and CO2: The Case of Zebrafish Nitrobindin”

De Simone G., Coletta A., Di Masi A., Coletta M., Ascenzi P.

Antioxidants 2022, 11(10), 1932; https://doi.org/10.3390/antiox11101932

20) “Citicoline Eye Drops Protect Trabecular Meshwork Cells from Oxidative Stress Injury in a 3D In Vitro Glaucoma Model.”

Vernazza S. , Passalacqua M., Tirendi S., Marengo B., Domenicotti C., Sbardella D., Oddone F., Bassi A. M.

International Journal of molecular science Int J Mol Sci 2022 Sep 27;23(19):11375. doi: 10.3390/ijms231911375.

21) Reviewing the evidence surrounding preservative-free tafluprost/timolol fixed-dose combination therapy in open angle glaucoma and ocular hypertension management: a focus on efficacy, safety and tolerability

Oddone F.

Expert Opin Drug Saf 2022 Oct;21(10):1259-1268.doi: 10.1080/14740338.2022.2135701. Epub 2022 Oct 26.

22) Assessment of a Vision-Based Technique for an Automatic Van Herick Measurement System

Fedullo T., Cassanelli D., Gibertoni G., Tramarin F., Quaranta L., Riva I., Tanga L., Oddone F., Rovati L.

IEEE Transactions on Instrumentation and Measurement, vol. 71, pp. 1-11, 2022, Art no. 2516111, doi: 10.1109/TIM.2022.3196323.

23) Detecting glaucoma from multi-modal data using probabilistic deep learning.

Huang X., Sun J., Gupta K., Montesano G., Crabb D.P., Garway-Heath D.F., Brusini P., Lanzetta P., Oddone F., Turpin A., McKendrick A.M., Johnson C.A., Yousefi S.

Front Med (Lausanne) 2022 Sep 29;9:923096. doi: 10.3389/fmed.2022.923096. eCollection 2022.

24) Targeting immunoproteasome in neurodegeneration: a glance to the future.

Tundo G. R., Cascio P., Milardi D., Santoro A.M., Graziani G., Lacal P.M., Bocedi A., Oddone F., Parravano M., Coletta A., Coletta M., Sbardella D.

Pharmacology & Therapeutics,2022,108329,ISSN 0163-7258, https://doi.org/10.1016/j.pharmthera.2022.108329.

25) “Efficacy of Nonpreserved Sodium Hyaluronate Artificial Tears in Dry Eye Disease Patients Treated with Prostaglandin Analogs for Primary Open-Angle Glaucoma: A Prospective,Nonrandomized, Open-Label Pilot Study”.

Coco G., Iannetta D., Febbraro I., Elmo E., Manni G.

J Ophthalmol. 2022 Dec 2;2022:1320996. doi: 10.1155/2022/1320996. eCollection 2022.

26) Disease Progression Pathways of Wet AMD: Opportunities for New Target Discovery.

Wolf AT., Harris A., Oddone F., Siesky B., Verticchio Vercellin A., Ciulla T.A.

Expert Opin Ther Targets 2022 Jan;26(1):5-12.doi: 10.1080/14728222.2022.2030706. Epub 2022 Feb 23.

27) “Structural and (Pseudo-)Enzymatic Properties of Neuroglobin: Its Possible Role in Neuroprotection”

De Simone G., Sbardella D., Oddone F., Pesce A., Coletta M., Ascenzi P.

Cells 2021, 10(12), 3366; https://doi.org/10.3390/cells10123366

28) ”Treatment of Open-Angle Glaucoma and Ocular Hypertension with the Fixed-Dose Combination of Preservative-Free Tafluprost/Timolol: Clinical Outcomes from Ophthalmology Clinics in Italy.”

Oddone F., Scorcia V., Iester M., Sisto D., De Cilla S., Bettin P., Cagini C., Figus M, Marchini G, Rossetti L., Rossi G, Salgarello T., Scuderi GL, Staurenghi G.; VISIONARY Study Group (Italy).

Clin Ophthalmol. 2022 Jun 1;16:1707-1719. doi: 10.2147/OPTH.S364880. eCollection 2022.

29) ”Rates of Visual Field Change in Patients With Glaucoma and Healthy Individuals—Findings From a Median 25-Year Follow-up—Reply”

Giammaria S., Chauhan Balwantray C.

JAMA Ophthalmol. Published online September 29, 2022. doi:10.1001/jamaophthalmol.2022.323

UR SEGMENTO ANTERIORE CON ANNESSI OCULARI

1) Comparison of different methods to calculate the axial length measured by optical biometry.

Savini G., Hoffer K.J., Carballo L., Taroni L., Schiano-Lomoriello D.

J Cataract Refract Surg. 2021 Sep 20. doi: 10.1097/j.jcrs.0000000000000821. Online ahead of print.

2) Comparison of a New Optical Biometer That Combines Scheimpflug Imaging With Partial Coherence Interferometry With That of an Optical Biometer Based on Swept-Source Optical Coherence Tomography and Placido-Disk Topography.

Chen S., Zhang Q., Savini G., Zhang S., Huang X., Yu J., Wang Y., Ning R., Huang J., Tu R.

Front Med (Lausanne). 2022 Feb 10;8:814519. doi: 10.3389/fmed.2021.814519. eCollection 2021

3) Intraocular lens power calculation with ray tracing based on AS-OCT and adjusted axial length after myopic excimer laser surgery.

Savini G., Hoffer K.J., Ribeiro FJ, Dias JM, Coutinho CP, Barboni P., Lomoriello DS.

J Cataract Refract Surg. 2022 Feb 2. doi: 10.1097/j.jcrs.0000000000000902. Online ahead of print.

4) “Corneal diameter measurements by 3 optical biometers and their effect on phakic intraocular lens sizing”.

Savini G., Lupardi E., Hoffer KJ, Aramberri J., Schiano-Lomoriello D.

J Cataract Refract Surg. 2022 May 26.doi: 10.1097/j.jcrs.0000000000000976. Online ahead of print.

5) “Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT”.

Chen H., Wang Z., Li K., Wang Y., Li X., Du L., Lin M., Savini G., Wang Q., Yu A., Chen S.

Front Med (Lausanne). 2022 May 19;9:907334. doi: 10.3389/fmed.2022.907334.

6) “Repeatability of new optical biometer and agreement with two validated optical biometers, all based on swept-source optical coherence tomography”

Galzignato A. , Lupardi E., Hoffer K.J., Piero Barboni, Schiano Lomoriello, Giacomo Savini

J Cataract Refract Surg. 2022 Aug 23.doi: 10.1097/j.jcrs.0000000000001023. Online ahead of print

7) “IOL Power Calculation in Eyes Undergoing Combined Descemet Membrane Endothelial Keratoplasty and Cataract Surgery”

Knutsson K. A., Savini G., Hoffer K. J., Lupardi E., Bertuzzi F., Taroni L., Schiano-Lomoriello D., Paganoni G., Rama P.

J Refract Surg. 2022 Jul;38(7):435-442. doi: 10.3928/1081597X-20220601-02. Epub 2022 Jul 1.

8) Optical biometry and IOL calculation in a commercially available optical coherence tomography device and comparison with Pentacam AXL.

Kanclerz P., Hoffer K. J., Bazylczyk N., Wang X., Savini G.

Am J Ophthalmol. 2022 Oct 14;246:236-241. doi: 10.1016/j.ajo.2022.09.022. Online ahead of print.

9)Comparison of the New Hoffer QST with 4 Modern Accurate Formulas.

Taroni L., Hoffer K.J., Pellegrini MK, Lupardi E., Savini G.

Journal of Cataract & Refractive Surgery ():10.1097/j.jcrs.0000000000001126, December 16, 2022. | DOI: 10.1097/j.jcrs.0000000000001126

10) “Reply: Intraocular lens power calculation with ray tracing based on AS-OCT and adjusted axial length after myopic excimer laser surgery”

Savini G., Hoffer K. J., Facs F., Ribeiro F., Dias, J M, Coutinho C., Barboni P., Schiano-Lomoriello D.

J Cataract Refract Surg. 2022 Sep 6.doi: 10.1097/j.jcrs.0000000000001056. Online ahead of print

11) ”Reply: Comparison of different methods to calculate the axial length measured by optical biometry”

Savini G., Hoffer K. J., Carballo L., Taroni L., Schiano-Lomoriello D.

J Cataract Refract Surg. 2022 Aug 1;48(8):978-979. doi: 10.1097/j.jcrs.0000000000000994

UR RETINA MEDICA

1) Update on Current and Future Management for Diabetic Maculopathy.

Patricia Udaondo; Mariacristina Parravano; Stela Vujosevic; Dinah Zur; Usha Chakravarthy.

Ophthalmol Ther. 2022 Apr;11(2):489-502. doi: 10.1007/s40123-022-00460-8. Epub 2022 Jan 31.

2) Optical Coherence Tomography Angiography In Central Retinal Vein Occlusion: Macular Changes And Their Correlation With Peripheral Nonperfusion At Ultra-Widefield Fluorescein Angiography.

Michele Cavalleri, Riccardo Sacconi, Mariacristina Parravano, Eliana Costanzo, Mario Pezzella, Francesco Bandello, Giuseppe Querques

Ophthalmologica. 2022 Feb 10. doi: 10.1159/000522503. Online ahead of print.

3)Choroidal Caverns in Stargardt Disease.

Mucciolo D.P., Giorgio D., Lippera M., Dattilo V., Passerini I., Pelo E., Sodi A., Virgili G., Giansanti F., Murro V.

Invest Ophthalmol Vis Sci. 2022 Feb 1;63(2):25. doi: 10.1167/iovs.63.2.25.

4) A common finding in foveal-sparing extensive macular atrophy with pseudodrusen (EMAP) implicates basal laminar deposits.

Serena Fragiotta, Mariacristina Parravano, Riccardo Sacconi, Eliana Costanzo, Pasquale Viggiano, Francesco Prascina, Vittorio Capuano, Giuseppe Querques.

Retina: February 21, 2022 doi: 10.1097/IAE.0000000000003463

5) Discerning Between Macular Hemorrhages Due to Macular Neovascularization or Due to Spontaneous Bruch’s Membrane Rupture in High Myopia: A Comparative Analysis Between OCTA and Fluorescein Angiography.

Battista M., Sacconi R., Borrelli E., Crepaldi A., Fantaguzzi F., Costanzo E., De Geronimo D., Parravano M., Bandello F., Querques G.

Ophthalmol Ther. 2022 Apr;11(2):821-831. doi: 10.1007/s40123-022-00484-0. Epub 2022 Feb 20.

6) Functional Correlates of Outer Retina Remodeling in Intermediate Age-Related Macular Degeneration Using Microperimetry.

Fragiotta S., Costanzo E., Viggiano P., De Geronimo D., Scuderi G., Varano M., Parravano M.

Invest Ophthalmol Vis Sci. 2022 Mar 2;63(3):16. doi: 10.1167/iovs.63.3.16.

7) “Choroidal modifications assessed by means of choroidal vascularity index after oral eplerenone treatment in chronic central serous chorioretinopathy”.

Toto L., Ruggeri M.L., Evangelista F., Viggiano P., D’Aloisio R., De Nicola C., Falconio G., Di Nicola M., Porreca A., Mastropasqua R.

Eye (London). 2022 May 19. doi: 10.1038/s41433-022-02091-6. Online ahead of print.

8) “Economic Aspects in the Management of Diabetic Macular Edema in Italy”

Calabrò G.E., Basile M., Varano M., Amore F., Ricciardi R., Bandello F., Cicchetti A.

Front Public Health. 2022 Jul 22;10:938987.doi: 10.3389/fpubh.2022.938987. eCollection 2022

9) “Optical Coherence tomography angiography characterization of evolving lesions in fellow eyes of exudative type 3 MNV patients”

Sacconi R., Forte P., Capuano V., Miere A., Costanzo E., Tombolini B., Fantaguzzi F., Jung C., Parravano M., Varano M., Souied E., Bandello F., Queques G.

Retina2022 Aug 12.doi: 10.1097/IAE.0000000000003598. Online ahead of print.

10) “In vivo assessment of associations between photoreceptors structure and macular perfusion in type 1 diabetes”

Viggiano P., Costanzo E., Giannini D., Fragiotta S., De Geronimo D., Giorno P., Picconi F., Frontoni S., Varano M., Parravano M.

Br J Ophthalmol. 2022 Sep 1;bjophthalmol-2022-321617.doi: 10.1136/bjo-2022-321617. Online ahead of print

11) “Towards a better understanding of non-exudative choroidal and macular neovascularization”

Sacconi R, Fragiotta S, Sarraf D, Sadda S R, Freund K Bailey, Parravano M, Corradetti G, Cabral D, Capuano V, Miere A, Costanzo E, Bandello F, Souied E, Querques G.

Prog Retin Eye Res. 2022 Aug 13;101113. doi: 10.1016/j.preteyeres.2022.101113. Online ahead of print

12) “Impact of Intravitreal Anti-VEGF Therapy on Microperimetry of the Retinal Nonperfusion Areas of Patients with Proliferative Diabetic Retinopathy”

Parravano M., De Geronimo D., Sacconi R., Giannini D., Costanzo E., Fragiotta S., Viggiano P., Querques G.

Ophthalmol Ther. 2022 Sep 17. doi: 10.1007/s40123-022-00568-x. Online ahead of print.

13) “Sub-retinal pigment epithelium tubules in non-neovascular age-related macular degeneration”

Fragiotta S., Parravano M., Sacconi R., Costanzo E., De Geronimo D., Prascina F., Capuano V., Souied E. H., Han I. C, Mullins R., Querques G.

Sci Rep. 2022 Sep 7;12(1):15198.doi: 10.1038/s41598-022-19193-6.

14) “Retinal Pigment Epithelium Atrophy after subretinal Voretigene Neparvovec-rzyl for RPE65-related disease: a 6-month follow-up”

Giansanti F., Mucciolo D. P., Sodi A., Giorgio D., Virgili G., Murro V.

Retina 2022 Sep 2.doi: 10.1097/IAE.0000000000003576. Online ahead of print.

15) “Relative ellipsoid zone reflectivity and its association with disease severity in age-related macular degeneration: a MACUSTAR study report”

Saßmannshausen M., Behning C., Isselmann B., Schmid M., Finger R.F., Holz F.G., Schmitz-Valckenberg S., Pfau M., MACUSTAR Consortium; Thiele S.

Sci Rep. 2022 Sep 2;12(1):14933.doi: 10.1038/s41598-022-18875-5.

16) Ocular biomarkers for Alzheimer’s Disease Dementia: An Umbrella Review of Systematic Reviews and Meta-analyses

Costanzo E., Lengyel I., Parravano M., Biagini I., Veldsman M, Badhwar A., Betts M., Cherubini A., Llewellyn DJ, Lourida I., MacGillivray T., Rittman T., Tamburin S., Tai XY, Virgili G.

JAMA Ophthalmol. 2022 Nov 17. doi: 10.1001/jamaophthalmol.2022.4845. Online ahead of print.

17) The state-of-the-art pharmacotherapeutic management of neovascular age-related macular degeneration

Servillo A., Zucchiatti I., Sacconi R., Parravano M., Querques L,, La Rubia P,, Prascina F,, Bandello F,, Querques G.

Expert Opin Pharmacother. 2022 Dec 5;1-10. doi: 10.1080/14656566.2022.2154145. Online ahead of print.

18) “Effect of intravitreal dexamethasone implant in treatment-naive and previously-treated patients with diabetic macular edema.

Nikolopoulou E., Sacconi R., Lorusso M., Costanzo E., Parravano M., Micelli Ferrari L., Ferrari TM., Querques G.

Eur J Ophthalmol 2022 Dec 1;11206721221143166. doi: 10.1177/11206721221143166. Online ahead of print.

19) The Association between vision impairment and depression: a systematic review of population-based studies

Virgili G., Parravano M., Petri D., Maurutto E., Menchini F., Lanzetta P., Varano M., Mariotti SP., Cherubini A., Lucenteforte E.

J Clin Med 2022 Apr 25;11(9):2412. doi: 10.3390/jcm11092412.

20) “Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials”.

Heier J. S., Khanani A. M., Quezada Ruiz C., Basu K., Ferrone P. J., Brittain C., Figueroa M .S., Lin H., Holz F G., Patel V., Lai T. Y .Y., Silverman D., Regillo C., Swaminathan B., Viola F., Cheung C .M .G., Wong T. Y., TENAYA and LUCERNE Investigators.

Lancet. 2022 Feb 19;399(10326):729-740. doi: 10.1016/S0140-6736(22)00010-1. Epub 2022 Jan 24.

21) ”Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials”

Wykoff CC, Abreu F., Adamis AP, Basu K., Eichenbaum DA, Haskova Z., Lin H., Loewenstein A., Mohan S., Pearce IA, Sakamoto T., Schlottmann PG, Silverman D., Sun JK, Wells JA, Willis JR, Tadayoni R.; YOSEMITE and RHINE Investigators

Lancet. 2022 Feb 19;399(10326):741-755. doi: 10.1016/S0140-6736(22)00018-6. Epub 2022 Jan 24.

22) ”Disease-specific assessment of Vision Impairment in Low Luminance in age-related macular degeneration – a MACUSTAR study report”.

Jan Henrik Terheyden , Susanne G Pondorfer , Charlotte Behning , Moritz Berger , Jill Carlton , Donna Rowen, Christine Bouchet , Stephen Poor , Ulrich F O Luhmann, Sergio Leal , Frank G Holz , Thomas Butt , John E Brazier , Robert P Finger , MACUSTAR consortium

Br J Ophthalmol. 2022 Mar 30;bjophthalmol-2021-320848. doi: 10.1136/bjophthalmol-2021-320848. Online ahead of print.

UR RETINA CHIRURGICA

1) ”Human Vitreous Collagen Fragments Dimension As a Function of Vitrectomy Cut Rate”.

Rossi T., Speciale A., Menichini P., Izzotti A., D’Agostino I., Trillo C., Telani S., Querzoli G., Ripandelli G.

Transl Vis Sci Technol. 2022 Mar 2;11(3):29.doi: 10.1167/tvst.11.3.29.

2) “Comparative Evaluation of Antimicrobial, Antiamoebic, and Antiviral Efficacy of Ophthalmic Formulations.”

Caruso C., Eletto D., Tosco A., Pannetta M, Scarinci F, Troisi M, Porta A.

Microorganisms. 2022 Jun 4;10(6):1156. doi: 10.3390/microorganisms10061156.PMID: 35744674

3) ”Silicone Oil Tamponade-Retina Contact in Highly Myopic Eyes With and Without Encircling Bands: A Computational Fluid Dynamics Study”.

Rossi T., Querzoli G., Badas MG, Angius F., Ripandelli G.

4) Transl Vis Sci Technol2022 Jun 1;11(6):1.doi: 10.1167/tvst.11.6.1.4) Comparison of retrobulbar, sub-tenon anesthesia and medial canthus episcleral anesthesia for 25-cauge posterior vitrectomy.

Roman-Pognuz D., Scarpa G., Virgili G., Roman-Pognuz E., Paluzzano G., Cavarzeran F.

Retina 2022 Jan 1;42(1):19-26. doi: 10.1097/IAE.0000000000003260.

5) “Bilateral optic neuritis as the presenting sign of post SARS-CoV-2 acute disseminated encephalomyelitis”.

Rossi T., Novi G., D’Agostino I., Di Cello L., Soldati M. R., Telani S., Ripandelli G.

Am J Ophthalmol Case Rep. 2022 Mar;25:101273. Doi: 10.1016/j.ajoc.2022.101273.Epub 2022 Feb 4

6) “Superficial and Deep Capillary Plexuses: Potential Biomarkers of Focal Retinal Defects in Eyes Affected by Macular Idiopatic Epiretinal Membranes? A Pilot Study”

Coppe A.M., Lapucci G., Buzzonetti L., Ripandelli G., Iarossi G.

Diagnostics (Basel). 2022 Dec 17;12(12):3205.doi: 10.3390/diagnostics12123205.

UR ONCOLOGIA E TOSSICOLOGIA OCULARE

1) Choroidal Abnormalities in Pediatric NF1: A Cohort Natural History Study

Eleonora Cosmo, Luisa Frizziero, Giacomo Miglionico, Chiara Sofia De Biasi, Marisa Bruno, Eva Trevisson, Ilaria Gabbiato, Giulia Midena, Raffaele Parrozzani.

Cancers (Basel). 2022 Mar 10;14(6):1423. doi: 10.3390/cancers14061423.

2) Case Report: Multiple Retinal Astrocytic Hamartomas in Congenital Disorder of Glycosylation-Ia.

Midena G., Pilotto E.

Front Med (Lausanne). 2022 Feb 14;9:697030. doi: 10.3389/fmed.2022.697030. eCollection 2022

3) Small Fibre Peripheral Alterations Following COVID-19 detected by Corneal Confocal Microscopy.

Edoardo Midena, Eleonora Cosmo, Anna Maria Cattelan, Chiara Briani, Davide Leoni, Alfio Capizzi, Vanessa Tabacchi, Raffaele Parrozzani, Giulia Midena and Luisa Frizziero.

Pers. Med. 2022, 12(4), 563; https://doi.org/10.3390/jpm12040563

4) Response to comment on “Intraocular fluid biomarkers (liquid biopsy) in human diabetic retinopathy.”

Midena E., Frizziero L., Midena G., Pilotto E.

Graefes Arch Clin Exp Ophthalmol. 2022 Mar;260(3):1041-1042.doi: 10.1007/s00417-021-05463-y.

5) Handheld Fundus Camera for Diabetic Retinopathy Screening: A Comparison Study with Table-Top Fundus Camera in Real-Life Setting.

Midena E., Zennaro L., Lapo C., Torresin T., Midena G., Pilotto E., Frizziero L.

J Clin Med. 2022 Apr 22;11(9):2352. doi: 10.3390/jcm11092352.

6) Retinal Microvascular and Neuronal Changes Are Also Present, Even If Differently, in Adolescents with Type 1 Diabetes without Clinical Diabetic Retinopathy2

Pilotto E., Torresin T., Leonardi F., De Rubalcava Doblas , Midena G., Moretti C., Midena E.

J Clin Med. 2022 Jul 8;11(14):3982.doi: 10.3390/jcm11143982.

7) “Hyper-reflective retinal foci as possible in vivo imaging biomarker of microglia activation in von Hippel-Lindau disease”

Pilotto E., Torresin T., Bacelle M. L., De Mojà G., Ferrara A M., Zovato S., Midena G., Modena E.

PLoS One. 2022 Aug 12;17(8):e0272318.doi: 10.1371/journal.pone.0272318. eCollection 2022.

8) “Proptosis secondary to bilateral extraocular muscle enlargement in Noonan syndrome with hypertrophic cardiomyopathy: A case report”

Marchione G., Pilotto E., Midena G.

Eur J Ophthalmol. 2022 Sep 5;11206721221125035.doi: 10.1177/11206721221125035. Online ahead of print.

9) “Corneal Confocal Microscopy as a Quantitative Imaging Biomarker of Diabetic Peripheral Neuropathy: A Review”

Cosmo E., Midena G., Frizziero L., Bruno M., Cecere M., Midena E.

J Clin Med 2022 Aug 31;11(17):5130. doi: 10.3390/jcm11175130

10) Determinants of Long-Term Survival in Metastatic Choroidal and Ciliary Body Melanoma: Long-Term Survival in Metastatic Ciliochoroidal Melanoma.

Rantala E.S., Parrozzani R., Hernberg M.M., Chiarion-Sileni V., Kivelä T.T., Midena E.

Am J Ophthalmol. 2022 Nov 1;246:258-272 doi: 10.1016/j.ajo.2022.10.017. Online ahead of print.

11) Ultra-wide-field fundus photography compared to ophthalmoscopy in diagnosing and classifying major retinal diseases.

Midena E., Marchione G., Di Giorgio S., Rotondi G., Longhin E., Frizziero L., Pilotto E., Parrozzani R., Midena G.

Sci Rep 2022 Nov 11;12(1):19287.doi: 10.1038/s41598-022-23170-4.

UR NEUROFISIOLOGIA DELLA VISIONE E NEUROFTALMOLOGIA

1) Bimodal sensory integration in migraine: A study of the effect of visual stimulation on somatosensory evoked cortical responses.

Sebastianelli G., Abagnale C., Casillo F., Cioffi E., Parisi V., Di Lorenzo C., Serrao M., Porcaro C., Schoenen J., Coppola G.

Cephalalgia, February 15, 2022 Research Articlehttps://doi.org/10.1177/03331024221075073

2) Genetic characteristics of 234 Italian patients with macular and cone/cone-rod dystrophy. Falsini B., Placidi G., De Siena E., Chiurazzi P., Minnella A.M., Savastano M.C., Ziccardi L., Parisi V., Iarossi G., Percio M., Piteková B., Marceddu G., Maltese P.E., Bertelli M.

Sci Rep. 2022 Mar 8;12(1):3774. doi: 10.1038/s41598-022-07618-1

3) “The pattern of retinal ganglion cell loss in Wolfram syndrome is distinct from mitochondrial optic neuropathies”.

Barboni P., Amore G., Cascavilla M.L., Battista M., Frontino G., Romagnoli M., Caporali L., Baldoli C., Gramegna L.L., Sessagesimi E., Bonfanti R., Romagnoli A., Scotti R., Brambati M., Carbonelli M., Starace V, Fiorini C, Panebianco R., Parisi V., Tonon C., Bandello F, Carelli V., La Morgia C.

Am J Ophthalmol.2022 Apr 19;S0002-9394(22)00119-2.doi: 10.1016/j.ajo.2022.03.019. Online ahead of print

4) “Visual system abnormalities in a case of non-syndromic, complete, isolated corpus callosum agenesis”.

Barbano L., Ziccardi L., Antonelli G., Tinelli E., Parisi V.

J Neurophthalmol.

5) “Capturing the pattern of transition from carrier to affected in Leber’s hereditary optic neuropathy”.

Carbonelli M., La Morgia C., Romagnoli M., Amore G., D’Agati P., Valentino M.L., Caporali L., Cascavilla M.L., Battista M., Borrelli E., Di Renzo A., Parisi V., Balducci N., Carelli V., Barboni P.

Am J Ophthalmol.2022 May 2;241:71-79.doi: 10.1016/j.ajo.2022.04.016. Online ahead of print.

6) “The monoclonal CGRP-receptor blocking antibody erenumab has different effects on brainstem and cortical sensory-evoked responses”.

Casillo F., Sebastianelli G., Di Renzo A., Cioffi E., Parisi V., Di Lorenzo C., Serrao M., Coppola G.

Cephalalgia. 2022 May 30;3331024221103811.doi: 10.1177/03331024221103811.

7) “Multifocal Electroretinogram Photopic Negative Response: A Reliable Paradigm to Detect Localized Retinal Ganglion Cells’ Impairment in Retrobulbar Optic Neuritis Due to Multiple Sclerosis as a Model of Retinal Neurodegeneration”.

Barbano L., Ziccardi L* , Antonelli G., Nicoletti CG, Landi D, Mataluni G., Falsini B , Marfia,GA Centonze D, Parisi V.

Diagnostics (Basel). 2022 May 6;12(5):1156.doi: 10.3390/diagnostics12051156.

8) “Visual stimulation and frequency of focal neurological symptoms engage distinctive neurocognitive resources in migraine with aura patients: a study of resting-state functional networks”

Coppola G., Corbelli I., Di Renzo A., Chiappiniello A., Chiarini P., Parisi V., Guercini G., Calabresi P., Tarducci R., Sarchielli P.

J Headache Pain. 2022 Jul 12;23(1):80. doi: 10.1186/s10194-022-01446-4.

9) “A Hypothalamic Mechanism Regulates the Duration of a Migraine Attack: Insights from Microstructural and Temporal Complexity of Cortical Functional Networks Analysis”.

Porcaro C., Di Renzo A., Tinelli E., Parisi V., Di Lorenzo C., Caramia F., Fiorelli M., Giuliani G., Cioffi E., Seri S., Di Piero V., Pierelli F., Di Lorenzo G., Coppola G.

Int J Mol Sci. 2022 Oct 31;23(21):13238. doi: 10.3390/ijms232113238.

10) Childhood-Onset Leber Hereditary Optic Neuropathy – Clinical and Prognostic Insights

Barboni P., La Morgia C., Cascavilla ML, Hong EH, Basstista M, Maiander A, Caporali L, Starace V, Amore G., Di renzo A., Carbonelli M, Nucci P., Jurkute N, Benson S Chen, Panebianco R, De Negri AM, Sadun F., Parisi V., Bandello B., Sadun Alfredo A., Carelli V., Yu-Wai-Man P.

Journal of Ophthalmologyhttps://doi.org/10.1016/j.ajo.2022.12.014

11) “Retinal and Visual Pathways involvement in carriers of Friedreich’s ataxia

Ziccardi L., Barbano L ., Antonelli G., Cioffi E., Di Renzo A., Gioiosa V., Marcotulli C., Grzybowski A., Casali C., Parisi V.

Diagnostics (Basel). 2022, 12(12), 3135; https://doi.org/10.3390/diagnostics12123135

UR LABORATORIO

1) Complement Mediators in Development to Treat Age-Related Macular Degeneration.

Nebbioso M., Franzone F., Lambiase A., Taurone S., Artico M., Gharbiya M., Greco A., Polimeni A.

Drugs Aging. 2022 Feb;39(2):107-118. doi: 10.1007/s40266-021-00914-x. Epub 2022 Jan 20.

2) SARS-CoV-2 infection after vaccination in Italian health care workers: a case report.

Cafiero C., Palmirotta R., Micera A., Ottaiano MP, Re A, Pedata F., Costagliola D., Ponticelli D,. Pisconti S., Schiavone B., Benincasa G.

Natl Acad Sci Lett. 2022 Mar 6 : 1–6. doi: 10.1007/s40009-022-01106-w PMID: 35283546

[Epub ahead of print]

3) Comment on Kopańska et al. Disorders of the Cholinergic System in COVID-19 Era- A Review of the Latest Research.

Cafiero C., Micera A., Re A., Schiavone B., Benincasa G., Palmirotta R.

Int J Mol Sci. 2022 Mar 4;23(5):2818. doi: 10.3390/ijms23052818.

4) Could Small Neurotoxins-Peptides be Expressed during SARS-CoV-2 Infection?

Concetta Cafiero , Alessandra Micera , Agnese Re , Loredana Postiglione , Andrea Cacciamani , Beniamino Schiavone , Giulio Benincasa , Raffaele Palmirotta

Curr Genomics. 2021 Dec 31;22(8):557-563. doi: 10.2174/1389202923666211221111527.

5) Biochemical Functions and Clinical Characterizations of the Sirtuins in Diabetes-Induced Retinal Pathologies”.

Taurone S., De Ponte C., Rotili D., De Santis E., Mai A., Fiorentino F., Scarpa S., Artico M., Micera A.

Int J Mol Sci. 2022 Apr 6;23(7):4048. doi: 10.3390/ijms23074048.

6) “Ocular surface toll like receptors in ageing”.

Di Zazzo A., De Piano M., Coassin M., Mori T., Balzamino BO, Micera A.

BMC Ophthalmol. 2022 Apr 22;22(1):185. doi: 10.1186/s12886-022-02398-8.

7) “Oxidative stress and visual system: a review”.

Taurone S., Ralli M., Artico M., Madia V.N., Scarpa S., Nottola S.A., Maconi A., Betti M., Familiari P., Nebbioso M., Costi R., Micera A.

EXCLI J. 2022 Mar 1;21:544-553. doi: 10.17179/excli2022-4663. eCollection 2022.

8) “Nerve Growth Factor (NGF) as Partaker in the Modulation of UV-Response in Cultured Human Conjunctival Fibroblasts”.

Esposito G., Balzamino B.O., Rocco M.L., Aloe L., Micera A.

Int J Mol Sci. 2022 Jun 6;23(11):6337. doi: 10.3390/ijms23116337.

9) “Association between Vitamin D Receptor Gene Polymorphisms and Periodontal Bacteria: A Clinical Pilot Study”

Cafiero C., Grippaudo C., Dell’Aquila M., Cimmino P., D’Addona A., De Angelis P, Ottaiano M P, Costagliola D, Benincasa G., Micera A, Santacroce L., Palmirotta R.

Biomolecules. 2022 Jun 15;12(6):833. doi: 10.3390/biom12060833.

10) Tissue remodeling in adult vernal keratoconjunctivitis

Micera A., Di Zazzo A., De Piano M., Sharma S., Mori T., De Gregorio C., Coassin M., Ferndandes M.

Exp Eye Res. 2022 Dec;225:109301. doi: 10.1016/j.exer.2022.109301. Epub 2022 Nov 3.

11) ”The usefulness of lutein/trypan blue vital dye for the staining of corneal endothelium: a pilot study on DMEK pretreated tissues”.

Colabelli Gisoldi R., Lodato G., Balzamino B. O., Esposito G., Micera A., Pocobelli A.

Graefes Arch Clin Exp Ophthalmol. 2022 Nov 29;1-9. doi: 10.1007/s00417-022-05909-x. Online ahead of print.

12) “Circulating and Salivary NGF and BDNF Levels in SARS-CoV-2 Infection: Potential Predictor Biomarkers of COVID-19 Disease-Preliminary Data”.

Biamonte F., Re A., Balzamino B.O., Ciasca G., Santucci D., Napodano C., Nocca G., Fiorita A., Marino M., Basile U., Micera A., Callà CAM.

J Pers Med. 2022 Nov 9;12(11):1877.doi: 10.3390/jpm12111877. J Pers Med. 36579579

LAVORI IN CONDIVISIONE

1) Insulin-Degrading Enzyme Is a Non Proteasomal Target of Carfilzomib and Affects the 20S Proteasome Inhibition by the Drug.

Tundo G.R., Sbardella D., Oddone F., Grasso G., Marini S., Atzori M.G., Santoro A.M., Milardi D., Bellia F., Macari G., Graziani G., Polticelli F., Cascio P., Parravano M., Coletta M.

Biomolecules. 2022 Feb 16;12(2):315. doi: 10.3390/biom12020315.

2) “High glucose induces an early and transient cytoprotective autophagy in retinal Müller cells”.

Mecchia C., Palumbo, A. De Luca, D. Sbardella, A. Boccaccini, L. Rossi, M. Parravano, M. Varano, A. M. Caccuri.

Endocrine. 2022 May 25. doi: 10.1007/s12020-022-03079-8. Online ahead of print

3) “A novel and atypical NF-KB pro-inflammatory program regulated by a CamKII-proteasome axis is involved in the early activation of Muller glia by high glucose”

Sbardella D., Tundo G.R., Mecchia A., Palumbo C., Atzori M. G., Levati L., Boccaccini A., Caccuri A. M., Cascio P., Lacal P.M., Graziani G,. Varano M., Coletta M., Parravano M.

Cell Biosci. 2022 Jul 16;12(1):108. doi: 10.1186/s13578-022-00839-x

4) Choroidal vascularity index in eyes with central macular atrophy secondary to age-related macular degeneration and Stargardt disease.

Corbelli E., Sacconi R., Battista M., Bacherini D., Miere A., Borrelli E., Costanzo E., Vella G., Parravano M., Ziccardi L., Sodi A., Rizzo S., Souied E.H., Bandello F., Querques G.

Graefes Arch Clin Exp Ophthalmol. 2022 Jan 20. doi: 10.1007/s00417-021-05337-3. Online ahead of print.

5) “Branch retinal artery occlusion caught in the act by an optical coherence tomography angiography image: case report”

Scarinci F., Cacciamani A., Ripandelli G., Parravano M.

BMC Ophthalmol. 2022 Jul 14;22(1):303.doi: 10.1186/s12886-022-02517-5.

6) “Biopsychosocial Illness Model: From the Lung to the Eye”

Scarinci F., Parravano M., Patacchioli F. R.

J Clin Med. 2022 Jul 25;11(15):4298.doi: 10.3390/jcm11154298

7) “Multimodal Study of PRPH2 Gene-Related Retinal Phenotypes”

Antonelli G., Parravano M., Barbano L., Costanzoa E., Bertelli M., Medori M. C., Parisi V., Ziccardi L.

Diagnostics (Basel).2022 Jul 31;12(8):1851.doi: 10.3390/diagnostics12081851

8) “The Narrative Medicine Approach in the Treatment of Diabetic Macular Edema: An Italian Experience”

Midena E., Polo Cm Frizziero L., Marini M. G., Lattanzio R., Vadalà M., Pilotto E., Varano M.

Int J Environ Res Public Health. 2022 Jul 30;19(15):9367.doi: 10.3390/ijerph19159367

9) ”Cortisol awake response imbalance as an indicator of acute central serous chorioretinopathy: relationship with choriocapillaris and choroidal features”

Scarinci F., Patacchioli F. R., Costanzo E.M., Parravano M.

Front. Med., 30 November 2022Sec. Ophthalmology https://doi.org/10.3389/fmed.2022.1030352

10) “Short-term in vitro ROS detection and oxidative stress regulators in epiretinal membranes and vitreous from idiopathic vitreoretinal diseases”.

Balzamino B.O., Dinice L., Cacciamani A., re A., Scarinci F., Bruno L., Cosimi P., Micera A.

BioMed Research International, vol. 2022, Article ID 7497816, 12 pages, 2022. https://doi.org/10.1155/2022/7497816

11) “Morphological and biomolecular targets in Retina and Vitreous from Reelin-deficient mice (Reeler): potential implications for Age-related Macular Degeneration in Alzheimer’s Dementia”.

Balzamino B.O., Esposito G., Marino R., Calissano P., Latina V., Amadoro G., Keller F., Caccimani A., Micera A.

Front. Aging Neurosci., 16 November 2022 Sec. Alzheimer’s Disease and Related Dementias

https://doi.org/10.3389/fnagi.2022.1015359

12) “Middle-Inner Macular Layers Dysfunction in a Case of Stellate Foveomacular Retinoschisis Detected by Abnormal Multifocal Photopic Negative Response Recordings”.

Barbano L., Antonelli G., Parravano M., Costanzo E., Parisi V., Ziccardi L.

Diagnostics (Basel). 2022 Nov 10;12(11):2753.doi: 10.3390/diagnostics12112753.

13) “Biallelic Inactivating TUB Variants Cause Retinal Ciliopathy Impairing Biogenesis and the Structure of the Primary Cilium”.

Ziccardi L., Niceta M., Stellacci , Ciolfi A., Tatti M., Brusselles A., Mancini C., Barbano L., Cecchetti S., Costanzo E., Cappa M., Parravano M., Varano M., Trataglia M., Cordeddu V.

J Mol Sci 2022 Nov 24;23(23):14656. doi: 10.3390/ijms232314656.

14) “Morpho-Functional Macular Assessment in a Case of Facioscapulohumeral Muscular Dystrophy: Photoreceptor Degeneration as Possible Cause for Reduced Visual Acuity over Three Years of Follow-Up”.

Parravano M., Costanzo E., Barbano L., Viggiano P., De Geronimo D., Antonelli G., Parisi V., Varano M., Ziccardi L.

Diagnostics 2022, 12(12), 2977; https://doi.org/10.3390/diagnostics12122977

15) “A novel algorithm for the evaluation of corneal nerve beadings by in vivo confocal microscopy in patients with type 1 diabetes mellitus”

Abicca I., Giannini D., Gilardi M., Roszkowska A.M., Parravano M., Picconi F., Frontoni S., Schiano-Lomoriello D.

Front Med (Lausanne) 2022 May 12;9:897259.doi: 10.3389/fmed.2022.897259. eCollection 2022.

16) ”Effects of circadian rhythm disruption on retinal physiopathology: considerations from a consensus of experts”

Parravano M., Eandi C.M., Figus M., Lupidi M., Menchini F., Nicolo’ M., Parisi V., Toto L., Viola F., Vujosevic S., Querques G.

Eur J Ophthalmol 2022 Sep;32(5):2489-2493.doi: 10.1177/11206721221106149. Epub 2022 Jun 3.

17) “Author Response: Relationship of Choroidal Vasculature and Choriocapillaris Flow With Alterations of Salivary α-Amylase Patterns in Central Serous Chorioretinopathy”.

Scarinci F., Patacchioli F.R., Costanzo E., Parravano M.

Invest Ophthalmol Vis Sci. 2022 Jun 1;63(6):10. Doi:10.1167/iovs.63.6.10

Pubblicazioni ultimo triennio

Le ultime pubblicazioni dell’IRCCS Fondazione G.B. Bietti per lo Studio e la Ricerca in Oftalmologia ETS.

Se vuoi consultare le pubblicazioni degli anni precedenti clicca qui

Pubblicazioni 2025

UR GLAUCOMA

1) “Vascular Density and Retinal Structure Relationships Across Sectors and Regions of the Optic Nerve in Patients With Primary Open Angle Glaucoma”

Ritzer L, Harris A, Arciero J, Siesky B, Fry B, Januleviciene I, Oddone F, Carnevale C, Eckrt G, Verticchio Vercellin A.

J Glaucoma. 2025 Apr 1;34(4): 267-274. https://doi.org/10.1097/IJG.0000000000002536

2) “Preservative-Free Bimatoprost 0.01% Ophthalmic Gel for Glaucoma Therapy: A Phase III Randomized Controlled Trial”

Muñoz-Negrete Francisco J , Tpouzis F, Oddone F, Nissle S, Rokicki D, Januleviciene I, Harasymowycz P, Stalmans I.

J Glaucoma. 2024 Jun 1;33(6):422-430. https://doi.org/10.1097/IJG.0000000000002371

3) “Safety and Longevity of Intraocular Pressure Control After Bimatoprost Implant Administration: Interim Analysis of a Phase 3b Clinical Trial (TRITON)”

Silverstein S M, Oddone F, Kolko M, Brinkmann C K, Christie W C, Bicket A K, Gous P NJ, Luebke J, Maram J, Nguyen A, Craven E R, Pu Y, Jiao J, BejanianM, Robinson MR, TRITON Studt Group

Drugs. 2025 Apr;85(4):557-570. https://doi.org/10.1007/s40265-025-02154-4

4) “A phase III study comparing preservative-free latanoprost eye drop emulsion with preserved latanoprost in open-angle glaucoma or ocular hypertension”

Baudouin C, Stalmans I, Bourne R, Larrosa JM, Schmickler S, Seleznev A, Oddone F, Phase III Study Group.

Eye (Lond). 2025 Feb 25. https://doi.org/10.1038/s41433-025-03646-z

5) “Italian glaucoma virtual clinics: Developing a consensus for remote patient management”.

Matarazzo F, Cutolo CA, Rabiolo A, Figus M, Fea A, Gandolfi S, Gizzi C, Manni G, Marchini G, Montesano G, Nucci C, Passaro ML, Romano D, Rossetti L, Sacchi M, Tanga L, Traverso CE, Triolo G, Virgili G, Oddone F, Costagliola C.

Acta Ophthalmol. 2025 Mar 17. https://doi.org/10.1111/aos.17484

6) “Medical and surgical treatment management in open angle glaucoma patients of Asian descent: A narrative review”.

Belamkar A V, Harris A, Wirotsko B, Rowe L, Oddone F, Carnevale C, Verticchio Vercelli A, Kanwar K, Wood K, Fabczak-Kubicka A, Siesky B

Eur J Ophthalmol. 2025 May 19:11206721251340435. https://doi.org/10.1177/11206721251340435

7) “Efficacy and Safety of XEN63 Gel Stent Implant over 6 Months for Treatment of Glaucoma”.

Sacchi M, Giammaria S, Roberti G, Tomaselli D, Monsellato G, Agnifili L, Posarelli C, Abbruzzese G, Ronchi L, Tatti F, Dore S, Giannaccare G, Nucci P, Pinna A, Figus M, Oddone F.

J Clin Med. 2025 Apr 28;14(9):3036. https://doi.org/10.3390/jcm14093036

8) “Artificial intelligence for glaucoma”.

Vemulapalli K, Gandhewar R, Safitri A, Ng S M, Michelessi, Azuara-Blanco A, Liu S H, Virgili G, Hu K.

Cochrane Database Syst Rev. 2025 Jun 17;6(6):CD016114. https://doi.org/10.1002/14651858.CD016114.

9) “Relationships Among Glaucoma, Cardiovascular Diseases, and Mortality”.

Quaranta L, Galbussera A A, Tettamanti M, Novella A, Pasina L, Fortino I, Leoni O, Oddone F, Giammaria S, Kużniak M, Weinreb R N, Nobili

Adv Ther 2025 Sep;42(9):4403-4417. https://doi.org/10.1007/s12325-025-03282-9

10) “The Effects of Age on the Human Tear Film Assessed with a Novel Imaging Device” Verticchio Vercellin A, Isserow L J, Rosen R B, Sidoti P A, Siesky B A,Wood K, Schanzer N, Oddone F, Carnevale C, Tak Yee Tania Tai, Chen M, Manusis K, Tai K, Brenner D, Kleiman N J, Potash S, Eckert G J, Antman

Diagnostics (Basel) 2025 Sep 6;15(17):2256. https://doi.org/10.3390/diagnostics15172256

11) “Evaluation of AI Tools Versus the PRISMA Method for Literature Search, Data Extraction, and Study Composition in Glaucoma Systematic Reviews: Content Analysis”

Meliante L A, Coco G, Rabiolo A, De Cillà S, Manni G.

JMIR AI. 2025 Sep 5:4:e68592. https://doi.org/10.2196/68592

12) “Low-concentration bimatoprost 0.01% and timolol 0.1% eye gel versus bimatoprost 0.03% and timolol 0.5% eye drops in open-angle glaucoma or ocular hypertension: a phase III randomised study”

Cordeiro M F, Oddone F, Mermeklieva E A, Rokicki DM, Nisslé S, Gosciniewicz P, Stalmans I.

Br J Ophthalmol. 2025 Oct 14:bjo-2025-327555. https://doi.org/10.1136/bjo-2025-327555

13) “Clinical recommendations for early identification of patients with open-angle glaucoma at higher risk of low adherence to topical treatment: An Italian Delphi consensus” Carassa R G, Pomponio G, Agnifili L, fea A M, Iester M, Marchini G, Martini E, Miglior S, Oddone F, Rossetti L, Sacchi M, Traverso C E, Figus M.

Acta Ophthalmol. 2025 Nov 17. https://doi.org/10.1111/aos.70024

14) Prognostic factors associated with progression of open-angle glaucoma in adults”. Piyasena M P, daka O, qureshi R, Roberti G, Michelessi M, liu S-H, Takwoingi Y, Azuara-Blanco A, Virgili G; supported by the Cochrane Eyes and Vision Group

Cochrane Database Syst Rev. 2025 Dec 10;12(12):CD015436. https://doi.org/10.1002/14651858.CD015436.pub2

UR SEGMENTO ANTERIORE CON ANNESSI OCULARI

1) “Comparison of intraocular lens power formulas for negative diopter intraocular lens implantation for high myopia”

Whang WJ, Koh K, Hoffer K J, Schiano Lomoriello D, Lupardi E, Taroni L, Tchah H, Savini G.

J Cataract Refract Surg. 2025 Feb 1;51(2):119-125. https://doi.org/00.1097/j.jcrs.0000000000001569

2) “The Influence of Anterior Chamber Depth on the Calculation of Piggyback Intraocular Lenses”.

Buonsanti D, Hoffer K J, Coutinho C P, Savini G.

Am J Ophthalmol. 2025 Apr: 272:161-165. https://doi.org/10.1016/j.ajo.2025.01.013

3) “Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer”

Li X, Lei C S, Ning R, Liu L, Chen A, Yang X, Savini G, Schiano Lomoriello D, Zhou X, Huang J.

Eye Vis (Lond). 2025 Feb 1;12(1):6. https://doi.org/10.1186/s40662-024-00422-0

4) “Influence of preoperative variables on the 3-month functional outcomes of the Vivity extended depth-of-focus intraocular lens: a prospective case series”.

Savini G, Galzignato A, Coutinho C P, Huang J, Wu Y, Barboni P, Dias J M, Ribeiro F J, Schiano Lomoriello D.

Eye Vis (Lond). 2025 Feb 2;12(1):8. https://doi.org/10.1186/s40662-024-00424-y

5) “Which Test Is Best: Evaluation of Traditional and Contemporary Statistical Tests for Analysis of Spherical Equivalent Prediction Error”.

Cannon N T, Savini G, Pantanelli S M, Hoffer K, Aristodemou P, Riaz K, Murphy D, Griffini D, Berry C, Debellemanière G, Gauvin M, Wallerstein A, Whang W J, Koh K, Negishi K, Hayashi K, Hipolito-Fernandes D, Cooke D L.

Am J Ophthalmol 2025 Feb 7:273:33-42. https://doi.org/10.1016/j.ajo.2025.01.022

6) “Repeatability of automatic measurements by a new spectral domain optical coherence biometer and agreement with a validated biometer”.

Grendele A, Galzignato A, Hoffer K J, Coutinho C P, Calossi F, Schiano Lomoriello D, Savini G.

J Cataract Refract Surg 2025 Mar 10. https://doi.org/10.1097/j.jcrs.0000000000001650

7) “A Pilot Case Series on the Use of a Large Mushroom-Shaped Corneal Graft for the Surgical Management of Post-Penetrating Keratoplasty Ectasia and Endothelial Failure”

Moramarco A, Fontana L, Di Geronimo N, Rapezzi G, Savini G, Viola P, Mete M, Romano V.

J Clin Med. 2025 Jan 8;14(2):343. https://doi.org/10.3390/jcm14020343

8) “Evaluation of a New Fully Automatic OLCR Biometer: Repeatability, Reproducibility, and Agreement with an SS-OCT Biometer”

Chak Seng Lei, Xinning Yang, Rui Ning, Jinxuan Xiahou , Xinyu Jiang, Savini G, Schiano Lomoriello D, Xingtao Zhou, Kexin Li, Jinhai Huang.

Ophthalmol Ther. 2025 May;14(5):1097-1109. https://doi.org/10.1007/s40123-025-01120-3

9) “Optical confirmation by a thick-lens formula of the optimized A-constant (as calculated by a thin-lens formula) of a new intraocular lens”.

Savini G, Nicolosi D, Hoffer K J, Coutinho C P, Curatolo M C, Schiano Lomoriello D.

J Cataract Refract Surg. 2025 Apr 10. https://doi.org/00.1097/j.jcrs.0000000000001671

10) “IOL Power Calculation Project: Accuracy of 36 Formulas”.

Voytsekhivskyy O V, Hoffer K J, Cooke D, Savini G.

Am J Ophthalmol. 2025 May 12:277:45-56. https://doi.org/10.1016/j.ajo.2025.05.004

11) “Comparison of IOL formula accuracy for eyes with prior scleral buckle surgery”.

Kong A W, Jeon M J, Lin S R, Bartlett J D, McCannel C A, Hoffer K J, Savini G, Nejad M.

J Cataract Refract Surg. 2025 Jun 9. https://doi.org/10.1097/j.jcrs.0000000000001715

12) “Machine Learning Applied to Visual Fields of Dominant Optic Atrophy Patients”. Coutinho C P, Zanchetta F, Carbonelli M, Battista M, Galzignato A, La Morgia C, Amore G, Romagnoli M, Savini G, Brotto L, Nucci P, Caporali L, Bandello F, Carelli V, Cascavilla M L, Barboni P.

Transl Vis Sci Technol. 2025 Jun 2;14(6):20. https://doi.org/10.1167/tvst.14.6.20

13) “Theoretical Influence of segmented axial length on IOL Power calculation in short eyes”.

Savini G, Hoffer K J, Nicolosi P D, Cooke D, Coutinho C P, Grendele A, Schiano Lomoriello D.

Journal of Cataract & Refractive Surgery: https://doi.org/10.1097/j.jcrs.0000000000001711

14) “Normative Values on Stromal Curvature, Power and Corneal-Stromal Curvature Ratios From a Hybrid AS-OCT”.

Wandelstein J A, Grendele A, Langenbucher A, Galzignato A, Coutinho C P, Pantanelli S, Riaz K M, Savini G.

Clin Exp Ophthalmol. 2025 May 22. https://doi.org/10.1111/ceo.14556

15) “Precision of Corneal Aberrometric Measurements With a New Hybrid Device and Comparison With a Scheimpflug/Placido Topography in Different Grades of Keratoconus”.

Rui Ning, Yizhou Yang, Huilin Xu, Kexin Li, Zheng Li, Yue Li, Savini G, Schiano Lomoriello D, Xingtao Zhou, Xiaoying Wang, Jinhai Huang.

J Refract Surg, 2025 May;41(5): e460-e471. https://doi.org/10.3928/1081597X-20250401-03

16) “Comparison of Anterior Segment Measurements With a New Swept-source Optical Coherence Tomography Biometer and a Scheimpflug-Placido Topographer”.

Chak Seng Lei, Xin Li, Huilin Xu, Rui Ning, Yiran Wang, Savini G, Schiano-Lomoriello D, Xingtao Zhou, Kexin Li, Jinhai Huang.

J Refract Surg. 2025 May;41(5): e413-e420. https://doi.org/10.3928/1081597X-20250317-03

17) “Reply to Comment on “IOL power calculation project: accuracy of 36 formulas.”: Accuracy of 36 IOL power calculation formulas”.

Voytsekhivskyy O V, Hoffer K J, Cooke D L, Savini G.

Am J Ophthalmol. 2025 Sep 23: S0002-9394(25)00512-4. https://doi.org/10.1016/j.ajo.2025.09.034

18) “Corneal epithelial aberrations: a novel diagnostic tool for keratoconus and forme fruste keratoconus”

Ning R, Seng Lei C, Yang X, Li, Y, Yang Y, Gustafsson I, Savini G, Schiano-Lomoriello D, Zhou X, Wang X, Huang J

Eye Vis (Lond) 2025 Aug 6;12(1):31. https://doi.org/10.1186/s40662-025-00449-x

19) “Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT”.

Seng Lei C, Jiang X, Yang X, Wang Q, Li K, Ning R, Savini G, Schiano Lomoriello D, Zhou X, Huang J.

Photodiagnosis Photodyn Ther 2025 Oct:55:104763. https://doi.org/10.1016/j.pdpdt.2025.104763

20) “Changes in corneal topography and corneal biomechanics in keratoconus after mydriasis”.

Yu J, Huang X, Ning R, Jiang X, Seng Lei C, Pan H, Xiahou J, Savini G, Schiano Lomoriello D, Zhou X, Huang J.

Ophthalmic Physiol Opt 2025 Sep 16. https://doi.org/10.1111/opo.70011

21) “Stromal Curvature, Power and Corneal-Stromal Curvature Ratios From a Hybrid AS-OCT in Eyes With Keratoconus”.

Wendelstein J A, Ostermaier A, Freller K, Grendele A, Savini G, Coutinho C P, Herber R, Luft N, Kassumeh S, Langenbucher A, Priglinger S.

Clin Exp Ophthalmol 2025 Sep 30. https://doi.org/10.1111/ceo.70001

22) “Accuracy of a novel ultrasound biomicroscope for measuring corneal epithelial thickness and agreement with an SD-OCT based device”.

Wang Y, Meng Q, Ning R, Yang X, Zhang S, Savini G, Schiano-Lomoriello D, Huang J, Chen S.

Photodiagnosis Photodyn Ther. 2025 Oct 9:56:105246. https://doi.org/10.1016/j.pdpdt.2025.105246

23) “Multicenter European Data of Anatomical Parameters of the Anterior Eye Segment Measured with an Optical Biometer”.

Niknahad A, Son H-S, Auffarth G U, Block L, Savini G, Coutinho C P, Fernandez J, Labuz G.

J Clin Med. 2025 Nov 19;14(22):8192. https://doi.org/10.3390/jcm14228192

24) “Accuracy of IOL Power Calculation in Eyes Needing a Myopic Target”

Biagini F, Hoffer K J, Cooke D L, Chierigo A, Forte P, Di Cello LO, Tarallo M, Schiano-Lomoriello D, Savini G.

J Refract Surg. 2025 Dec;41(12): e1312-e1318. https://doi.org/10.3928/1081597X-20251023-02

25) “Comparison of Posterior Corneal Curvature Measurements by Four Different Tomographers”.

Grendele A, Galzignato A, Hoffer K J, Coutinho C P, Yeo T K, Gaglione M, Schiano-Lomoriello D, Savini G.

J Refract Surg. 2025 Dec;41(12):e1330-e1338. https://doi.org/10.3928/1081597X-20251027-02

UR RETINA MEDICA

1) “Faricimab versus the standard of care for neovascular age-related macular degeneration in Italy: an indirect treatment comparison”

Galeone C, Turati F, Nicolò M, Parravano M, Vujosevic S, Bianchino L, Sicari E, Lanzetta P.

Drug Target Insights. 2024 Dec 12:18:105-111. https://doi.org/10.33393/dti.2024.3213

2) “Real-world evidence of anti-VEGF therapies in patients with neovascular age-related macular degeneration in Italy: The RADIANCE study”

Parravano M, Viola F, Nicolò M, Vujosevic S, Bianchino L, Sicari E, Villa G, Lanzetta P. Eur J Ophthalmol. 2025 Feb 3:11206721241310628. https://doi.org/10.1177/11206721241310628

3)”Retinal detachment incidence in refractive lens exchange versus cataract surgery: uncommon versus rare – systematic review and meta-analysis”

Passaro M L, Kilic D, Virgili G, Romano V, Lucenteforte E, Dick B, Taneri S.

Br J Ophthalmol. 2025 Feb 27: bjo-2024-326592. https://doi.org/10.1136/bjo-2024-326592

4)”Type 3 Macular Neovascularization in Age-related Macular Degeneration: Baseline Predictors of 3-Year Macular Atrophy Development”

Sacconi R, Forte P, Corradetti G, Costanzo E, Capuano V, Bousquet E, Beretta F, Iannuzzi S, Polito M S, Nicolò M, Parravano M, Souied E, Sarraf D, Sadda S V, Bandello F, Querques G.

Ophthalmol Retina. 2024 Nov 19: S2468-6530(24)00541-4. https://doi.org/10.1016/j.oret.2024.11.011

5)”Prevalence of dry eye disease among children: a systematic review and meta-analysis” Zou Y, Li D, Virgili G, Condon N, Piyassena P, PrakalapakomS G, Zhang R, Zhao Z, Fai Chan V, Yu M.

BMJ Open Ophthalmol. 2025 Feb 19;10(1):e002014. https://doi.org/10.1136/bmjophth-2024-002014

6)”Retinal Dystrophies Associated with Mutations in the RP1 Gene: Genotype-Phenotype Correlations”

Spagnuolo V, Piergentili M, Passerini I, Murro V, Mucciolo D P, Giorgio D, Maccari M, Pelo E, Biagini I, Giansanti F, Virgili G, Sodi A.

Curr Issues Mol Biol. 2025 Mar 20;47(3):212. https://doi.org/10.3390/cimb47030212

7)“Microcystoid Macular Edema in Epiretinal Membrane: Not a Retrograde Maculopathy”

Govetto A, Francone A, Luccini S, Garavaglia S, Carini E, Virgili G, Radice P, Vogt D, Edwards M, Spaide R F, Romano M R.

Am J Ophthalmol. 2025 Apr: 272: 48-57. https://doi.org/10.1016/j.ajo.2024.12.027

8) “Real-World Intravitreal Aflibercept 2 mg Treatment of Macular Oedema Secondary to Retinal Vein Occlusion in Italy: 24-Month Results from the AURIGA Observational Study”.

Grassi M O, Russo A, Vadalà M, Allmeier H, Machewitz T, Varano M, AURIGA Study Investigators

Ophthalmologica. 2025 Apr 9:1-14. https://doi.org/10.1159/000545534

9)“Comparison of Methods to Deliver Mitomycin C in Trabeculectomy Surgery: A Systematic Review and Meta-Analysis”.

Ghilardi A, Fan S, Mercieca K, Virgili G, De Cillà S, Rabiolo A.

Ophthalmol Glaucoma. 2025 Apr 19: S2589-4196(25)00072-9. https://doi.org/10.1016/j.ogla.2025.04.004

10) “Femtosecond laser-assisted in situ keratomileusis for the correction of residual ametropia after penetrating keratoplasty: 1-year follow-up”

Mucciolo D P, Albani G, Terracciano L, Branchetti M, Luchetti L, Murro V, Virgili G, Giansanti F.

Front Ophthalmol (Lausanne). 2025 Apr 11:5:1562555. https://doi.org/10.3389/fopht.2025.1562555

11) “Evaluating the burden of caregivers of patients with visual impairment: a multicenter pilot study in Italian visual rehabilitation centers”

Virgili G, Ferron F, Bartolomei F, Van Nispen R, Costanzo E, Ciaffoni G L, Rellini E, Turco S, Piepoli M, Di Pietro S, Fortini S.

Front Public health, 06 June 2025 Sec. Public Mental Health Volume 13, 2025 – https://doi.org/10.3389/fpubh.2025.1530172

12)“Geographic Atrophy and Peripheral Atrophy: Quantitative Analysis with Ultra-Widefield Autofluorescence”

De Geronimo D, Parravano M, Sacconi R, Costanzo E, Varano M, Querques G. Ophthalmologica. 2025 Apr 8:1-7. https://doi.org/10.1159/000544958

13)“Behçet’s disease: A review of the ophthalmologic findings reported in Behçet’s original descriptions”.

Accorinti M, Gilardi M, Cecere M, Ohno S, De Geronimo D.

Saudi J Ophthalmol. 2025 Feb 14;39(1):41-46. https://doi.org/10.4103/sjopt.sjopt_216_24

14)”Updates on novel and traditional OCT and OCTA biomarkers in nAMD”.

Crincoli E, Parravano M, Sacconi R, Costanzo E, Polito M S, Ferro Desideri L, Querques G. Eye (Lond). 2025 Jun;39(9):1662-1672. https://doi.org/10.1038/s41433-025-03801-6

15)”Evidence and Consensus-Based Imaging Guidelines in Multifocal Choroiditis With Panuveitis and Punctate Inner Choroiditis-Multimodal Imaging in Uveitis (MUV) Taskforce Report 5”.

Gangaputra S, Agarwal A, Ossewaarde-van Norel J, Tsui E, E Thoren J, De-la-Torre A, Altraweel M, Biswas J, Sadda S, Invernizzi A, Agrawal R, Shanta J G, Accorinti M, Fawzi A, Jabs D A, Sarraf D, Gupta V, Multimodal Imaging in Uveitis (MUV) Task force

Am J Ophthalmol. 2025 Apr 25:276:272-285. https://doi.org/10.1016/j.ajo.2025.04.018

16)“Albumin Folding Changes Affect the Microfluidic Interfacial Broadening Revealed by Surface Plasmon Resonance”.

Calcagno D, Perina M L, Distefano A, Parravano M, Licciardello A, Tuccitto N, Grasso G. Chemistry Methods, March 2025 volume 5, issue 3 https://doi.org/10.1002/cmtd.202400034

17)“Intravitreal faricimab for diabetic macular oedema and neovascular age-related macular degeneration: general considerations and practical recommendations by an expert panel of Italian retina specialists”.

Borrelli E, Boscia F, Lanzetta P, Lupidi M, Mastropasqua R, Nicolò M, Parravano M, Ricci F, Staurenghi G, Vadalà M, Viola F, Vujosevich S, Bandello F.

Eye (Lond). 2025 Sep 25. https://doi.org/10.1038/s41433-025-03997-7

18) “Multimodal imaging to assess disease activity and predict fluid resolution in wAMD Treated with Brolucizumab: The IMAGINE Study”.

Lupidi M, Bandello F, Vujosevic S, Parravano M, Bacherini D, Minnella A M, Giansanti F, Ascardi C, Staurenghi G.

Ophthalmol Ther. 2025 Oct;14(10):2497-2510. https://doi.org/10.1007/s40123-025-01229-5

19) “Visual acuity in various phenotypes of intermediate age related macular degeneration (AMD) in a multicentre cohort study in Europe- INTERCEPT-AMD report 1”.

Gurudas S, Marques I, Girmens J F, lechanter Y, Parravano M, Berger L, Agostini H, Barrao S, Tsiroukis E, Mones J, Sararols L, Silva R, Scholl H, Lommatzsch A, Stanzel B, Vujosevic S, Sivrapasad S, INTERCEPT-AMD Study Group

Eye (Lond). 2025 Oct;39(14):2655-2663. https://doi.org/10.1038/s41433-025-03895-y

20) “Unilateral reticular Pseudodrusen: Clinical features and potential protective factors” Desideria L F, Anguita R, Sacconi R, Beretta F, Corradetti G, Feo A, Dobovsek D, Parravano M, Capuano V, Souied E, Sarraf D, Zinkernagel M, Querques G.

Retina. 2025 Jun 23. https://doi.org/10.1097/IAE.0000000000004575

21) “Evaluating High Intraocular Pressure Criteria for Failure in Glaucoma Surgery: Impact on Estimated Success and Visual Field Rates”.

Rabiolo A, Triolo G, Servillo A, Khaliliyeh D, Sang W J, Morales E, Rossetti L, Anand N, Montesano G, Virgili G, Caprioli J, De Cillà S.

Am J Ophthalmol. 2025 Jul 3:279:21-33. https://doi.org/10.1016/j.ajo.2025.05.054

22) “Systematic Review of Clinical Utility of Multimodal Imaging in Noninfectious Posterior Uveitis: MUV Project Report 3”.

Accorinti M, Berkenstock M K, Cicinelli M V, Davis J L, De La Torre A, Fabiani C, Gangaputra S, Gupta V, Janetos T M, Leal I, Reynolds J M, Schlaen A.

Am J Ophthalmol. 2025 Jul 12:279:56-77. https://doi.org/10.1016/j.ajo.2025.07.002

23) “Progression Patterns in Foveal-Sparing Geographic Atrophy With Double-Layer Sign Due to Neovascularization or Basal Laminar Deposits”.

Fragiotta S, Parravano M, Sacconi R, Polito M S, Cioffi B, Rissotto F, Beretta F, Costanzo E, Romano E, Capuano V, Souied E H, Querques G.

Invest Ophthalmol Vis Sci. 2025 Aug 1;66(11):16. https://doi.org/10.1167/iovs.66.11.16

24) “Global gender disparities in access to refractive error services: A systematic review and meta-analysis”.

Mavi S, Whitestone N, Chan V F, Congdon N, Ramke J, Piyasena M P, Gordon I, Patnaik J L, Cherwek D H, Negash H, Li D, Little J A, Virgili G.

Ophthalmology. 2025 Sep 9: S0161-6420(25)00556-1. https://doi.org/10.1016/j.ophtha.2025.08.031

25) “Angioid streaks-related choroidal neovascularization: Clinical features, multimodal imaging-based differential diagnosis, and optimized treatment strategies”.

La Rosa A, Feo A, Bousquet E, Cabral D, Fouad Y, Parravano M, Romano M R.

Surv Ophthalmol. 2025 Sep 17: S0039-6257(25)00169-9. https://doi.org/10.1016/j.survophthal.2025.09.012

26) “Uveitic Glaucoma Interest Group Recommendations for Uveitis-Related Ocular Hypertension and Glaucoma Management”.

Pantcheva M B, Gangaputra S, Sieck E, Accorinti M, Neumann R, Ang B C H, Barton K, Chu D S, grigg J, Kempen J H, Liebman J M, Munoz-Negrete F J, Nguyeb Q D, Palestine A G, Thorne J, Van Meerwiik C, Yang P, De Smet M D.

Ocul Immunol Inflamm. 2025 Sep 19:1-15. https://doi.org/10.1080/09273948.2025.2542286

27) “International consensuses and controversies on causes, diagnosis and management of diabetic macular edema (DME)”.

NG DSC, Ruamviboonsuk P, Apte R S, Bajimaya S, Chan CKM, Chang A, Cheung CY, Chen SJ, Chaudhary V, Chaikitmongkol V, Chhablani J, Das T, Huang S S, Jonas J B, Lai TYY, Lai CC, Ma J, Munk MR, Narayanan R, Radke NV, Sagong M, Sabanayagam C, Sivaprasad S, Shimura M, Sonoda KH, Sun J K, Tan GSW, Takkar B, Virgili G, Vujosevic S, Wang M, Yu S Y, Zhang X, Zhang J, Wong TY, Lam DSC.

Prog Retin Eye Res. 2025 Sep 24:101406. https://doi.org/10.1016/j.preteyeres.2025.101406

28) “Baseline factors that are associated with change in visual acuity in intermediate AMD over two years in a multicentre cohort study in Europe- INTERCEPT-AMD Report 2” Gurudas S, Marques I, Girmns J-F, lechanteur Y, Parravano M, Berger L, Agostini H, Barrao S, Tsiroukis E, Mones J, Sararols L, Silva R, Scholl H PN, Lommatzsch A, Stanzel B, Vujosevic S, Sivaprasad S, INTERCEPT-AMD Study Group

Eye (Lond). 2025 Dec;39(18):3324-3332. https://doi.org/10.1038/s41433-025-04062-z

29) “Surface plasmon resonance unveils diffusion fingerprints of biomolecular mixtures in ocular fluid models”.

Calcagno D, Olivieri V, Parravano M, Tuccitto N, Grasso G.

Biosens Bioelectron. 2026 Jan 15:292:118080. https://doi.org/10.1016/j.bios.2025.118080

30) “Structural Biomarkers Influencing Drusenoid Pigment Epithelial Detachment Lifecycle and the Development of Late Macular Degeneration”.

Fragiotta S, Querques G, Polito M S, Costanzo E, Rossi T, Varano M, Pannarale F M, Sakurada Y, Parravano M.

Ophthalmol Sci. 2025 Oct 15;6(1):100977. https://doi.org/10.1016/j.xops.2025.100977

31) “Choroidal measurements in patients affected by PXE-related retinopathy”.

Mucciolo D P, Murro V, Giorgio D, Boraldi F, Pavese L, Quaglino D, Sodi A, Branchetti M, Pollazzi L, Virgili G, Giansanti F.

Front Ophthalmol (Lausanne). 2025 Oct 6:5:1647390. https://doi.org/10.3389/fopht.2025.1647390

32) “Early prediction of macular neovascularization phenotypes and prognostic evolution” Fragiotta S, Parravano M, Costanzo E, De Geronimo D, Varano M, Borrelli E, Barresi C, Sacconi R, Querques G.

Graefes Arch Clin Exp Ophthalmol. 2025 Nov 12. https://doi.org/10.1007/s00417-025-07024-z

33) “Comparative diagnostic accuracy of photographic methods for detecting diabetic retinopathy: A systematic review and meta-analysis”.

Dattilo V, Polito M S, Parravano M, Donati M C, Peto T, Orso M, Virgili G, Cushley L.

Eur J Ophthalmol. 2025 Dec 8:11206721251406434. https://doi.org/10.1177/11206721251406434

34) “Patient preferences for adverse effects of intraocular pressure-lowering eye drops. Results from a Danish large-scale discrete choice experiment: These adverse effects matter to the patients”.

Von Spreckelsen A, Kjaer T, Reimann M, Top-Pedersen C, Porsborg Andersen M, Virgili G, Azuara-Blanco A, Gyrd-Hansen D, Kolko M.

Acta Ophthalmol. 2025 Dec 4. https://doi.org/10.1111/aos.70047

UR RETINA CHIRURGICA

1) “Internal Limiting Membrane Flaps in Macular Hole Surgery: A Systematic Review and Individual Participant Data Meta-analysis”

Tzoumas N, MCNally T W, The B L, Zaman M, Yorston D, Lois N, Chaudhary V, Steel D H, ILM Flap Study Group

Ophthalmol Retina. 2025 Feb 7:S2468-6530(25)000557. https://doi.org/10.1016/j.oret.2025.02.003

2) Comparing the Efficiency of Fluid Infusion Systems for Pars Plana Vitrectomy”

Rossi T, Querzoli G, Angelini G B, Santoro V, Pellizzaro C, Steel D H, Parravano M, Romano M R.

Transl Vis Sci Technol. 2025 May 1;14(5):10. https://doi.org/10.1167/tvst.14.5.10

3) Comparing the Efficiency of Valved Trocar Cannulas for Pars Plana Vitrectomy”

Rossi T, Querzoli G, Angelini G B, Pellizzaro C, Santoro V, Rosari G, Parravano M, Romano M R.

Bioengineering (Basel). 2025 Apr 19;12(4):431. https://doi.org/10.3390/bioengineering12040431

4) Fluid dynamics in the vitreus chamber during infusion in ophthalmic surgery: a numerical study”.

Ledda P G, Badas M G, Rossi T, Querzoli G

Flow. 2025; 5:E30. https://doi.org/10.1017/flo.2025.10021

5) “Silicone oil removal-related vision loss”.

Ruggieri M L, Romano M R, Rossi T, Bacherini D, Ferrara M, Placenti L, Giansanti F, Quarta A, Mastropasqua R.

Surv Ophthalmol. 2025 Aug 19:S0039-6257(25)00142-0. https://doi.org/10.1016/j.survophthal.2025.08.011

6) “Proliferative vitreoretinopathy and outer retinal folds in rhegmatogenous retinal detachment. Insights into retinal remodeling”

Affatato M, Castelluzzo A M, Rapino G, Cucciniello P, Giugliano C, Picotto C, Campagna G, Rossi T, Ziccardi L, Dell’Omo R.

Retina. 2025 Jul 24. https://doi.org/10.1097/IAE.0000000000004631

7) “Safety and effectiveness of vital dyes for intraocular surgery”.

Romano M R, Ferrara M, Szurman P, Spadaro A, Levis H J, Govetto A, Rossi T, Platania C B, Januschowski K, Bucolo C, Romano V.

Prog Retin Eye Res. 2025 Nov 1:110:101412. https://doi.org/10.1016/j.preteyeres.2025.101412

UR ONCOLOGIA E TOSSICOLOGIA OCULARE

1) “Neurofibromatosis type 1 (NF1)-related ocular signs: new insights on their prevalence, incidence and genotype-phenotype correlation in NF1 children”.

Midena E, Cosmo E.

Am J Ophthalmol. 2025 Mar 5: S0002-9394(25)00110-2. https://doi.org/10.1016/j.ajo.2025.02.044

2) “Letter to the Editor Regarding “Intraretinal Hyper-Reflective Foci Are Almost Universally Present and Co-Localize With Intraretinal Fluid in Diabetic Macular Edema”.

Midena E, Frizziero L.

Invest Ophthalmol Vis Sci. 2025 Feb 3;66(2):59. https://doi.org/10.1167/iovs.66.2.59

3) “Disorganisation of inner retinal layers in diabetic macular oedema: is it time to standardise this OCT biomarker?”

Danieli L, Midena G, Frizziero L, Midena E.

Br J Ophthalmol. 2025 Feb 27: bjo-2024-326843. https://doi.org/10.1136/bjo-2024-326843

4) “Hyperreflective retinal foci: definition and role of an invaluable OCT sign”.

Frizziero L, Midena G, Danieli L, Torresin T, Perfetto A, Parrozzani R, Pilotto E, Midena E J Clin Med. 2025 Apr 27;14(9):3021. https://doi.org/10.3390/jcm14093021

5) “Artificial intelligence-based assessment of imaging biomarkers in epiretinal membrane surgery”.

Mariotti C, Mangoni L, Mui A, Fella M, Mogetta V, Bongiovanni G, Rizzo C, Chhablani J, Midena E, Lupidi M

Eur J Ophthalmol. 2025 Apr 27:11206721251337139. https://doi.org/10.1177/11206721251337139

6) “Flow Cytometry, Cytology and Histology in the Diagnosis of Ocular Lymphomas: 15-year Monocentric Experience with a Focus on Ocular Lymphomas”.

Falda A, Davanzo V, Marino D, Molin C, Fogar P, Turkman J, Zuin J, Finotto S, Pizzi M, Midena G, Vianello F, Dei Tos AP, Montagnana, M Parrozzani R, Basso D.

October 2025 Clinical Chemistry and Laboratory Medicine https://doi.org/10.1515/ccl,-2025-0216

7) “Neuroinflammation in radiation maculopathy: a pathophysiologic and imaging perspective”.

Midena G, Parrozzani R, Bruno M, Pilotto E and Midena E

Cancers (Basel). 2025 Jul 31;17(15):2528. https://doi.org/10.3390/cancers17152528

8) “Microperimetry for Monitoring Geographic Atrophy: Is It the Solution?”.

Midena E, Pilotto E.

Retina. 2025 Oct 1;45(10):1823-1825. https://doi.org/10.1097/IAE.0000000000004584

9) “BRIDGE: a multi-stakeholder workstream focused on assessing new clinical endpoints in ophthalmology clinical trials [Building Research Innovations and Developing Global Endpoints”.

Bridge Study Group

Eye (Lond). 2025 Aug;39(12):2337-2339. https://doi.org/10.1038/s41433-025-03832-z

10) “What Lies beneath Diabetic Macular Edema: Latent Phenotypic Clustering and Differential Treatment Responses to Intravitreal Therapies”.

Cicinelli M V, Leonardo B, Maiucci G, Martino G, Ziafati M, Bousyf S, Frizziero L, Lattanzio R, Midena E, Bandello F.

Ophthalmol Sci. 2025 Oct 14;6(1):100975. https://doi.org/10.1016/j.xops.2025.100975

11) “Fixation Stability as a Surrogate for Reading Abilities in Age-Related Macular Degeneration: A Perspective”.

Molin C, Midena E, Convento E, Midena G, Pilotto E.

J Clin Med. 2025 Nov 9;14(22):7941. https://doi.org/10.3390/jcm14227941

12) “Development and standardisation of ‘time-in-range’ measurement for clinical endpoints in retinal diseases”.

Frizziero L, Barrat J, Gemmy Cheung C M, Korol A, Midena E, Talks J, tsilimbaris M, Pearce I, Kozak I.

Eye (Lond). 2025 Dec 16. https://doi.org/10.1038/s41433-025-04112-6

UR NEUROFISIOLOGIA DELLA VISIONE E NEUROFTALMOLOGIA

1) “Variable Ophthalmologic Phenotypes Associated with Biallelic Loss-of-Function Variants in POMGNT1”.

Ziccardi L, Barbano L, D’Andrea M, Bruselles A, Dell’Aquila C, Niceta M, Mancini C, Leone A, Carvetta M, Albanese M, Stellacci E, Tartaglia M, Cordeddu V.

Int. J. Mol. Sci. 2025, 26, 3278. https://doi.org/10.3390/ijms26073278

2) “MRI-based analysis of the microstructure of the thalamus and hypothalamus and functional connectivity between cortical networks in episodic cluster headache”. Abagnale C, Di Renzo A, Giuliani G, Sebastianelli G, Casillo F, Ziccardi L, Parisi V, Di Lorenzo C, Serrao M, Caramia F, Di Piero V, Coppola G.

J Headache Pain. 2025 Jan 15;26(1):12. https://doi.org/10.1186/s10194-024-01920-1

3) Assessment of hypothalamic macrostructure in episodic cluster headache: a volumetric segmentation MRI study”.

Chiffi D, Di Renzo A, Giuliani G, Abagnale C, Altieri M, Sebastianelli G, Casillo F, Di Piero V, Coppola G, Caramia F.

Radiol Med. 2025 Jun 27. https://doi.org/10.1007/s11547-025-02041-8

4) “Structural and Functional Assessment of the Macular Inner Retinal Layers in Multiple Sclerosis Eyes Without History of Optic Neuropathy”.

Barbano L, Ziccardi L, Dell’Aquila C, D’Andrea M, Nicoletti C G, Landi D, Mataluni G, Di Renzo A, Buttari F, Dell’Omo R, Marfia G A, Centonze D, Parisi V.

J Clin Med. 2025 Aug 21;14(16):5919. https://doi.org/10.3390/jcm14165919

5) “Biallelic BAIAP3 Variants Are Associated with Isolated Retinitis Pigmentosa”. Cordeddu V, Flex E, Mignini L, Bruselle A, Cecchetti S, Messina E, Arasi M B, Carvetta M, Straface E, Leone A, Guadagnolo D, D’Asdia M C, Nebbioso M, Bellacchio E, Dell’Aquila C, Ziccardi L, Pizzuti A, De Luca A, Tartaglia M.

Int J Mol Sci. 2025 Aug 25;26(17):8244. https://doi.org/10.3390/ijms26178244

6) “Volume of the hypothalamus and its subunits in patients with episodic migraine without aura during interictal periods”.

Giardina I, Di Renzo A, Chiffi D, Giovannini F, Giuliani G, Sebastianelli G, Casillo F, Abagnale C, Altieri M, Di Piero V, Coppola G, Caramia F.

J Headache Pain. 2025 Aug 4;26(1):176. https://doi.org/10.1186/s10194-025-02118-9

7) “Structural alterations in occipital cortices in trigeminal neuralgia: a voxel- and surface-based morphometric MRI study”.

Caramia F, Di Renzo A, Fiorelli M, De Stefano G, Di Stefano G, Boccia M, Tullo MG, Cartocci G, Gianni C, Truini A.

J Headache Pain. 2025 Jul 16;26(1):162. https://doi.org/10.1186/s10194-025-02104-1

8) “Brain imaging in migraine with and without aura: Similarities and differences”. Casillo F, Sebastianelli G, Abagnale C, Di Renzo A, Ziccaardi L, Parisi V, Coppola G. 2025 Sep; 45 (9): 3331024251365807. https://doi.org/10.1177/03331024251365807

9) “3T MRI thalamic segmentation reveals no macrostructural changes in interictal episodic migraine without aura compared to healthy controls”.

Giardina I, Di Renzo A, Chiffi D, Giuliani G, Sebastianelli G, Casillo F, Abagnale C, Ziccardi L, Pucci A, Parisi V, Altieri M, Di Piero V, Coppola G, Caramia F.

J Headache Pain. 2025 Nov 7;26(1):243. https://doi.org/10.1186/s10194-025-02196-9

10) “Novel Finding of Retinal Aneurysmal Alterations in Patients Undergoing Fingolimod Therapy for Multiple Sclerosis”.

Menna F, Barbano L, Dell’Aquila C, D’Andrea M, Parisi V, Ziccardi L.

Neurol Ther. 2025 Nov 9. https://doi.org/10.1007/s40120-025-00854-3

UR LABORATORIO

1) “VEGFR3 pathway in corneal transplantation”

Laborante M, Micera M, Gaudenzi D, De Luca A, De Gregorio C, Cutrupi F, Esposito G, Balzamino BO, Laborante A, Coassin M, Di Zazzo A.

Acta Ophthalmol. 2025 Feb 6. https://doi.org/10.1111/aos.17457

2) “Oncological Treatment Adverse Reaction Prediction: Development and Initial Validation of a Pharmacogenetic Model in Non-Small-Cell Lung Cancer Patients” Cafiero C, Palmirotta R, Martinelli C, Micera A, Giacò L, Persiani F, Morrione A, Pastore C, Nisi C, Modoni G, Galeano T, Guarino T, Foggetti I, Nisticò C, Giordano A, Pisconti S.

Genes (Basel). 2025 Feb 24;16(3):265. https://doi.org/10.3390/genes16030265

3) Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life”.

Latina V, De Introna M, Malerba F, Florio R, Omar B O, Di Natale G, Sciacca MFM, Pappalardo G, Micera A, Pignataro A, Calissano P, Amadoro G.

Acta Neuropathol Commun. 2025 May 29;13(1):121. https://doi.org/10.1186/s40478-025-02022-y

4) “Ceruloplasmin and Ferritin Changes in Ocular Fluids from Patients with Vitreoretinal Diseases: Relation with Neuroinflammation and Drusen Formation.” Esposito, G. Cosimi, P. Balzamino, B.O. Bruno, M. Squitti, R, Dinice, L. Scarinci, F. Rongioletti, M.C.A. Cacciamani, A. Micera, A.

Int. J. Mol. Sci. 2025, 26, 6307. https://doi.org/10.3390/ijms26136307

5)“The Zebrafish as a Model for Ocular Translational Research: From Retinal Repair to Regeneration”

Balzamino B O, Severino M, Cafiero C, Coassin M, Di Zazzo A, Micera A.

Cells. 2025 Sep 8;14(17):1405. https://doi.org/10.3390/cells14171405

6)”NGF, BDNF, and NO in Myopic Subjects: Relationships Between Aqueous Levels and Lens Epithelial Cells’ Activation”

De Piano M, Cacciamani A, Scarinci F, Squitti R, Cosimi P, Bruno M, Ripandelli G, Palanza P, Micera A.

Int J Mol Sci. 2025 Jul 1;26(13):6350. https://doi.org/10.3390/ijms26136350

7) “Biomolecular Aspects of Reelin in Neurodegenerative Disorders: An Old Candidate for a New Linkage of the Gut-Brain-Eye Axis”

Balzamino B O, Biamonte F, Micera A.

Int J Mol Sci. 2025 Jul 30;26(15):7352. https://doi.org/10.3390/ijms26157352

8) “Zinc Therapy in Mild Cognitive Impairment: Cognitive Stabilization in Pharmacodynamically Responsive Patients in the ZINCAiD Trial”

Squitti R, Benussi A, Fostinelli S, Geviti A, Rivolta J, Vnetriglia M, Micera A, Rongioletti M, Ghidoni R, santilli M, Granzotto A, Albanese A, Binetti G, Sensi S L, Borroni B. Biomolecules 2025 Sep 1;15(9):1268. https://doi.org/10.3390/biom15091268

9) “A Revised Concept for Ocular Surface Imprinting: Easy-to-Use Device for Morphological and Biomolecular-Based Differential Diagnosis”

Balzamino B O, Ghezzi I, Sgrulletta R, Colabelli Gisoldi R A M, Pocobelli A, Di Zazzo A, Zollo L, Micera A.

Diagnostics (Basel). 2025 Oct 21;15(20):2660. https://doi.org/10.3390/diagnostics15202660

10) “Secondary dry eye disease in breast cancer patients: a pilot study”.

Grasso A, Salerno A, Micera A, Ferraro A, Fornaro E, Esposito G, Coassin M, Altomare V, Di Zazzo A.

Breast. 2025 Dec 8:85:104677. https://doi.org/10.1016/j.breast.2025.104677

UR LABORATORIO DI PROTEOMICA

1) “Nitrite binding to myoglobin and hemoglobin: Reactivity and structural aspects” Ascenzi P, De Simone G, Zingale GA, Coletta M.

J Inorg Biochem. 2025 Apr: 265: 112829. https://doi.org/10.1016/j.jinorgbio.2025.112829

2) “Label-free determination of diffusion coefficients at the nanoscale through modelling of the Surface Plasmon Resonance signal”

Zingale G A, Pandino I, Calacagno D, Perina M L, Tuccitto N, Grasso G

PLoS One. 2025 Jan 7;20(1):e0312594. https://doi.org/10.1371/journal.pone.0312594

3) “Broad-Spectrum Diffusion Coefficient Measurements via Surface Plasmon Resonance: From Thermodynamics to Protein Conformational Disorders”

Basile G S, Calcagno D, Tuccitto N, Sbardella D, Grasso G.

Chemphyschem. 2025 Jun 29: e2500138. https://doi.org/10.1002/cphc.202500138

4)”Proteins and Carbon Dioxide Struggle Against Peroxynitrite”.

De Simone G, Di Masi A, Tundo M G, Messias A, Estrin D A, Coletta M, Ascenzi P. Biofactors 2025 Jul-Aug;51(4):e70030. https://doi.org/10.1002/biof.70030

5) “Horse heart mini- and full length-myoglobin: pH effects on CO binding”.

Coletta M, Zingale G A, De Simone G, De Sanctis G, Quadrotta V, Polticelli F, Ascenzi P.

J Inorg Biochem 2025 Sep 19:274:113081. https://doi.org/10.1016/j.jinorgbio.2025.113081

6) “Dissecting NO Association and Dissociation Dynamics of Myoglobin, Hemoglobin, and Heme-Model Compounds”.

Coletta M, De Simone G, Pandino I, Bocesi A, Ascenzi P. Inorg Chem. 2025 May 19;64(19): 9365-9371. https://doi.org/10.1021/acs.inorgchem.5c00239

7)”SpectraSage unveils specific proteolytic patterns of 20S on mono-ubiquitylated Tau proteoforms involved in neurodegeneration”.

Zingale G A, Pandino I, Trivellato D, Cavaterra D, Munari F, Grasso G, Bell P A, Oddone F, Bocedi A, Coletta M, Assfalg M, D’Onofrio M, Tundo G R, Sbardella D.

Chem Sci 2025 Aug 20;16(36):16979-16992. https://doi.org/10.1039/d5sc04240b

8) “Tetra-anionic porphyrin mimics protein-protein interactions between regulatory particles and the catalytic core, allosterically activating human 20S proteasome”

Santoro A M, D’Urso A, Cunsolo A, Tkachuk O, Milardi D, Purrello R, Tundo G R, Sbardella D, Osmulsky P A, Gaczynska, Coletta M, Fattorusso C.

J Enzyme Inhib Med Chem.2025 Dec;40(1):2482892. https://doi.org/10.1080/14756366.2025.2482892

9) SUMO-2 activity is inhibited by non-covalent interactions with the Aβ peptide: an exploration of potential pathogenic mechanisms in Alzheimer’s disease”.

Ciaffaglione V, Grasso G, Lanza V, Sciacca MFM, Zimbone S, Giuffrida M L, Iacobucci C, Di Ianni A, Calcagno D, Grasso G, Alloni A, Orsini F, Fraser P, Fioriti L, Milardi D.

Int J Biol Macromol 2025 Sep;323(Pt 1):146632. https://doi.org/10.1016/j.ijbiomac.2025.146632

10) “Dissection of Nitric Oxide binding pathway in Nitrobindins reveals hidden structural details”

Iagatti A, Messias A, De Simone G, Sebastiani F, Patrizi B, Bocesi A, Estrin D, Ascenzi P, Fossi P, Coletta M.

Int J Biol Macromol. 2025 Nov;331(Pt 2):148406. https://doi.org/10.1016/j.ijbiomac.2025.148406

11) “The Interplay between the Ubiquitin-Proteasome System and oxidative Stress: A Future Perspective in Eye Diseases”.

Tundo G R, Zingale G A, Pandino I, Peroni E, Sbardella D, Bocedi A.

Antioxidants 2025, 14(12), 1475; https://doi.org/10.3390/antiox14121475

12) “Proton-linked effects on the axial coordination in ferric and ferrous horse heart cytochrome c.”

Sebastiani F, Bocedi A, De Simone G, Notari S, Gambardella G, Sbardella D, Smulevich G, Ascenzi P, Coletta M.

Protein Sci. 2025 Nov;34(11): e70233. https://doi.org/10.1002/pro.70233

LAVORI IN CONDIVISIONE

1) “Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects”

Giammaria S, Pandino I, Zingale G A, Atzori M A, Cavaterra D, Cecere M, Michelessi M, Roberti G, Tanga L, Carnevale C, Verticchio Vercellin A, Siesky B, Harris A, Grasso G, Bocedi A, Coletta M, Tundo G R, Oddone F, Sbardella D.

ACS Omega. 2025 Apr 9;10(15):14866-14883. https://doi.org/10.1021/acsomega.4c10035

2) “Oxidative Stress and Complement Activation in Aqueous Cells and Vitreous from Patient with Vitreoretinal Diseases: Comparison Between Diabetic ERM and PDR” Dinice L, Cosimi P, Esposito G, Scarinci F, Cacciamani A, Cafiero C, Placentino L, Ripandelli G, Micera A.

Antioxidants (Basel). 2025 Jul 8;14(7):841. https://doi.org/10.3390/antiox14070841

3) “Retinal Vessel Coronal Displacement in Intermediate Age-Related Macular Degeneration”

Parravano M, Fragiotta S, Polito M S, Varano M, Querzoli G, Rossi T.

J Clin Med. 2025 Aug 26;14(17):6030. https://doi.org/10.3390/jcm14176030

4) “Expression of Reelin, Aβ1-42, Tau and FTH1 in Idiopathic Epiretinal Membranes: Exploring the Link Between Reelin and Neurodegenerative Biomarkers”.

Balzamino B O, Graziana E, Cosimi P, Squitti R, Amadoro G, Latina V, Ripandelli G, Cacciamani A, Micera A.

Biomolecules. 2025 Aug 18;15(8):1187. https://doi.org/10.3390/biom15081187

5) “High-glucose stimulation triggers early transcription of a panel of proinflammatory mediators in rat Muller glia cells and retina primary explants”.

Tundo G R, Atzori M G, Boccaccini A, Cavaterra D, Bocesi A, Graziani G, Marini S, Lacal P M, Villa M, pricci F, Varano M, Parravano M, Sbardella D.

Acta Diabetol. 2025 Jul 4. https://doi.org/10.1007/s00592-025-02543-x

6) “Is the Laminar Flow From the Vitrectomy Infusion Cannula Potentially Harmful?” Rossi T, Querzoli G, Ledda P G, Balzamino B O, Pellizzaro C, Rosari G, Steel D H, Mastropasqua R, Romano M R, Micera A.

Transl Vis Sci Technol. 2025 Nov 3;14(11):29. https://doi.org/10.1167/tvst.14.11.29

7) “Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome”.

Zingale G A, Giammaria S, Pandino I, Placentino L, Ripandelli G, Tundo G R, Grasso G, Bocedi A, Bell P A, Rossi T, Sbardella D.

Sci Rep. 2025 Oct 14;15(1):35848. https://doi.org/10.1038/s41598-025-19857-z

8) “DRSplus retinographer in patients with diabetes: a comparison study by consensus grading, Reading Center and Artificial Intelligence”.

Parravano M, Costanzo E, De Geronimo D, Varano M, Rossi T, Rui C E, Gazzina S E, Querques G.

Retina. 2025 Nov 12. https://doi.org/10.1097/IAE.0000000000004734

9) “AI-Assisted OCT Clinical Phenotypes of Diabetic Macular Edema: A Large Cohort Clustering Study”

Midena E, Lupidi M, Toto L, Covello G, Veritti D, Pilotto E, Cicinelli M V, Lattanzio R, Figus M, Midena G, Danieli L, et al.

J Clin Med. 2025 Nov 7;14(22):7893. https://doi.org/10.3390/jcm14227893

10) “Functional Assessment of Inner and Outer Macular Layers in Idiopathic Epiretinal Membrane”

Parisi V, Ziccardi L, Dell’Aquila C, Barbano L, D’Andrea M, Giammaria S, Ripandelli G, Placentino L, Dell’Omo R, Rossi T.

Invest Ophthalmol Vis Sci. 2025 Dec 1;66(15):29. https://doi.org/10.1167/iovs.66.15.29

Pubblicazioni 2024

UR GLAUCOMA

1) “Physiology-Enhanced Data Analytics to Evaluate the Effect of Altitude on Intraocular Pressure and Ocular Hemodynamics” 

Vercellin AV, Harris A, Belamkar A, Zukerman R, Carichino L, Szopos M, Siesky B, Quaranta L, Bruttini C, Oddone F, Riva I, Guidoboni G. 

Photonics. 2022 Mar;9(3):158. doi: 10.3390/photonics9030158. Epub 2022 Mar 5. 

2) “Comparison Between 24-2 ZEST and 24-2 ZEST FAST Strategies in Glaucoma and Ocular Hypertension Using a Fundus Perimeter” 

Romano D, Oddone F, Montesano G, Fogagnolo P, Colizzi B, Tanga L, Giammaria S, Rui C, Rossetti LM. 

J Glaucoma. 2024 Mar 1;33(3):162-167. doi: 10.1097/IJG.0000000000002358. Epub 2024 Jan 12. 

3) “The Eye as the Window to the Heart: Optical Coherence Tomography Angiography Biomarkers as Indicators of Cardiovascular Disease” 

Kellner RL, Harris A, Ciulla L, Guidoboni G, Verticchio Vercellin A, Oddone F, Carnevale C, Zaid M, Antman G, Kuvin JT, Siesky B. 

J Clin Med. 2024 Jan 31;13(3):829. doi: 10.3390/jcm13030829. 

4) “Eye diseases: when the solution comes from plant alkaloids” 

Lorrai R, Cavaterra D, Gianmaria S, Sbardella D, Tundo GR, Boccaccini A. 

Planta Med. 2024 Mar 7. doi: 10.1055/a-2283-2350. Online ahead of print. 

5) “Preservative-free Bimatoprost 0.01% Ophthalmic Gel for Glaucoma Therapy. A Phase III Randomized Controlled Trial” 

Muñoz-Negrete FJ, Topouzis F, Oddone F, Nisslé S, Rokicki D, Januleviciene I, Harasymowycz P, Stalmans I. 

J Glaucoma. 2024 Mar 4. doi: 10.1097/IJG.0000000000002371. Online ahead of print. 

6) “Glaucoma, Pseudoexfoliation and Hearing Loss: A Systematic Literature Review”

Meliante L A, Piccotti G, Tanga L, Giammaria S, Manni G, Coco G.

Clin. Med. 2024, 13, 1379. https://doi.org/10.3390/jcm13051379

7)“24-Hour Evaluation of the Effectiveness and Tolerability of Preservative-Free Tafluprost-Timolol Fixed Combination in Open-Angle Glaucoma or Ocular Hypertensive Patients Previously Treated with Preserved Latanoprost”. 

Oddone F, Tanga L, Giammaria S, Sabbatini L, Strianese A, Ferrazza M, Rossetti LM. 

Clinical Ophthalmology 2024:18; 1751-1760. Doi: 10.2147/OPTH.S462672    

8) “Nitric Oxide Binding Geometry in Heme-Proteins: Relevance for Signal Transduction” 

De Simone G, Di masi A, Sbardella D, Ascenzi P, Coletta M.  

Antioxidants 2024, 13(6), 666; https://doi.org/10.3390/antiox13060666 

9) “Uveoscleral Outflow Routes after MicroPulse Laser Therapy for Refractory Glaucoma: An Optical Coherence Tomography Study of the Sclera” 

Agnifili L, Palamini A, Brescia L, Porreca A, Oddone F, Tanga L, Ruggeri M L, Quarta A, Mastropasqua R, Di Nicola M, Pastropasqua L.  

Int. J. Mol. Sci. 2024, 25(11), 5913; https://doi.org/10.3390/ijms25115913 

10) “Exploring the relationship between accommodation and intraocular pressure: a systematic literature review and meta-analysis” 

Ambrosini G, Poletti S, Roberti G, Carnevale C, Manni G, Coco G.  

Graefes Arch Clin Exp Ophthalmol. 2024 Jul 22. doi: 10.1007/s00417-024-06565-z. Online ahead of print. 

11) “Diagnostic Capability of OCTA-Derived Macular Biomarkers for Early to Moderate Primary Open Angle Glaucoma” 

Verticchio Vercellin A, Harris A, Oddone F, Carnevale C, Siesky BA, Arciero J, Fry B, Eckert G, Sidoti PA, Antman G, Alabi D, 1, Coleman-Belin JC,  Pasquale LR.  

J Clin Med. 2024 Jul 18;13(14):4190.  doi: 10.3390/jcm13144190. 

12) “HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape” 

Gottardi Zamperla M, Illi B, Barbi V, Cencioni C, Santoni D, Gagliardi S, Garofalo M, Zingale GA, Pandino I, Sbardella D, Cipolla L, Sabbioneda S, Farsetti A, Ripamonti C, Fossati G, Steinkühler X, Gaetano C, Atlante S.  

Clin Epigenetics. 2024 Aug 18;16(1):109. doi: 10.1186/s13148-024-01725-8. 

13) “The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells’ Ubiquitylome” 

Tundo GR, Cavaterra D, Pandino I, Zingale GA, Giammaria S, Boccaccini A, Michelessi M, Roberti G, Tanga L, Carnevale C, Figus M, Grasso G, Coletta M, Bocedi A, Oddone F, Sbardella D.  

Int J Mol Sci. 2024 Sep 17;25(18):10017. doi: 10.3390/ijms251810017. 

14) “Asymmetric Glaucoma and Corresponding Hearing Impairment” 

Meliante L A, Coco G, Francavilla B, Bianchi M, Velletrani G, Di Girolamo S, Manni G. 

J Clin Med. 2024 Oct 30;13(21):6501. doi: 10.3390/jcm13216501. 

15) “The impact of different forms of exercise on intraocular pressure, blood flow, and the risk for primary open angle glaucoma” 

Sidoti M, Harris A, Coleman-Belin J, Verticchio Vercellin A, Antman G, Oddone F, Carnevale C, Tessone I, Siesky B. 

Eur J Ophthalmol. 2024 Nov 8:11206721241296027. doi: 10.1177/11206721241296027. Online ahead of print. 

16) “Italian XEN-Glaucoma Treatment Registry (XEN-GTR): Effectiveness and Safety at 36 Months of XEN45 Implant” 

Oddone F, Roberti G, Giammaria S, Posarelli C, Mastropasqua L, Agnifili L, Micelli Ferrari T, Pace V, Sacchi M, Altafini R, Scuderi G, Perdicchi A, Carnevale C, Fea A, Figus M.  

Clin. Med. 2024, 13(23), 7370; https://doi.org/10.3390/jcm13237370

17) “Label-Free determination of diffusion coefficients at the nanoscale through modelling of the Surface Plasmon Resonance Signal” 

Zingale G A, Pandino I, Calcagno D, Perina M.P., Tuccitto N, Grasso G 

Published: January 7, 2025 https://doi.org/10.1371/journal.pone.0312594

UR SEGMENTO ANTERIORE CON ANNESSI OCULARI

1)”Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium” 

Rui Ning, Yiran Wang, Zhenyu Xu, Ingemar Gustafsson, Jiawei Li, Giacomo Savini, 

Domenico SchianoLomoriello, Yichen Xiao, Aodong Chen, Xiaoying Wang, Xingtao Zhou and 

Jinhai Huang 

Eye Vis (Lond). 2024 Jan 2;11(1):1. doi: 10.1186/s40662-023-00368-9. 

 2) “The Influence of Lens Position, Vault Prediction, and Posterior Cornea on Phakic Posterior Chamber Intraocular Lens Power” 

Wendelstein JA, Yeo TK, Hinterberger S, Seiler TG, Dick HB, Savini G, Langenbucher A, Taneri S. 

Am J Ophthalmol. 2024 Jan 11:261:7-18. doi: 10.1016/j.ajo.2024.01.008. Online ahead of print. 

3) “Evaluation of a new dynamic real-time visualization 25 kHz swept-source optical coherence tomography based biometer”. 

Yu J, Lin X, Huang X, Xu Z, Ning R, Li K, Savini G, Schiano-Lomoriello D, Zhou X, Huang J. 

Eye Vis (Lond). 2024 Mar 4;11(1):9. doi: 10.1186/s40662-024-00377-2. 

4) “Differences Between Simulated Keratometry and Total Corneal Power in Eyes With Keratoconus and a Formula to Improve IOL Power Calculation Results” 

Catarina P Coutinho, Domenico Schiano-Lomoriello, Cosimo Mazzotta, Marco Ferrise, Kenneth J Hoffer, Filomena J Ribeiro, João Mendanha Dias, Giacomo Savini 

J Refract Surg. 2024 Apr;40(4):e253-e259. doi: 10.3928/1081597X-20240311-06. Epub 2024 Apr 1. 

5) “Targeted next-generation sequencing analysis in Italian patients with keratoconus” 

Lombardo M, Camellin U, Gioia R, Serrao S, Scorcia V, Roszkowska A M, Lomabrdo G, Bertelli M, Medori M C, Alunni Fegatelli D, Vestri A, Mencucci R, Schiano Lomoriello D.  

Eye (Lond). 2024 Apr 29. doi: 10.1038/s41433-024-03090-5. Online ahead of print. 

6) “Meridional analysis for calculation of the toric power of phakic IOLs” 

Buonsanti D, Coutinho C P, Hoffer K J, Savini G.  

Eur J Ophthalmol. 2024 Apr 18:11206721241245747. doi: 10.1177/11206721241245747. Online ahead of print. 

 7) “Infectious Keratitis: Characterization of Microbial Diversity through Species Richness and Shannon Diversity Index” 

Schiano Lomoriello D, Abicca I, Contento L, Gabrielli F, Alfonsi C, Di Pietro F, Papa F T, Ballesteros.Sanchez A, Sanchez Gonzalez J M, Rocha De Lossada C, Mazzotta C, Giannaccare G, Bonzano C, Borroni D.  

Biomolecules. 2024 Mar 24;14(4):389. doi: 10.3390/biom14040389. 

8) “Evaluation of the Agreement Between a New Pyramid Wavefront Sensor Aberrometer and Scheiner-Smirnov Aberrometers” 

Yizhou Yang, Rui Ning, Shuoyu Xu, Jinxuan Xiahou, Jiawei Li,  Savini G,  Schiano Lomoriello D, Xingtao Zhou, Jinhai Huang 

J Refract Surg. 2024 Apr;40(4):e218-e228. doi: 10.3928/1081597X-20240311-02. Epub 2024 Apr 1. 

9) “Comparison of Intraocular Lens Power Prediction Accuracy Between 2 Swept-Source Optical Coherence Tomography Biometry Devices” 

Sorkin N ,  Zadok  R, Savini G ,  Kan-Tor Y ,  Benjamini Y , Levinger E,  Bardugo J , Abulafia A  

Am J Ophthalmol. 2024 Apr 20:265:156-164. doi: 10.1016/j.ajo.2024.04.013. Online ahead of print. 

10) “Evaluating keratometry and corneal astigmatism data from biometers and anterior segment tomographers and mapping to reconstructed corneal astigmatism” 

Langenbucher  A,  Taroni L ,  Coutinho C P ,  Cayless A, Szentmáry N ,  Hoffmann P , Wendelstein J , Savini G  

Clin Exp Ophthalmol. 2024 May 13. doi: 10.1111/ceo.14387. Online ahead of print. 

11) “An analysis of the factors involved in IOL decentration after phacoemulsification using CASIA 2 anterior segment optical coherence tomography” 

De Paula A, Gattazzo I, Savini G, Schiano Lomoriello G, Corsi A.  

Int Ophthalmol. 2024 Apr 24;44(1):194. doi: 10.1007/s10792-024-03126-5. 

12) “Immediate Sequential Bilateral Implantable Collamer Lens Surgery Is Safe and Effective” 

Russo A, Filini O, Mertens E, Daya S M, Conti F, Carones F, Festa G, Boldini A, Savini G.  

J Refract Surg. 2024 May;40(5):e313-e320. doi: 10.3928/1081597X-20240326-01. Epub 2024 May 1. 

13) “Analysis of the ESCRS Calculator’s Prediction Accuracy” 

Sorkin N, Zadok R, Totah H, Savini G, Ribeiro F, Findl O, Buonsanti D, Raimundo M, Abulafia A.  

J Cataract Refract Surg. 2024 Jun 28. doi: 10.1097/j.jcrs.0000000000001512. Online ahead of print. 

14) “Reply to comment on: Recommendation for presbyopia-correcting intraocular lenses: A Delphi consensus statement by the ESASO study group” 

Romano V, Madrid-Costa D, Alfonso J F, Alio J, Allan B, Angunawela R, Auffarth G, Carones F, Khoramnia R, Moore J, Nanavaty M A, Savini G, Pagano L, Romano M R, Virgili G, Fernandez-Vega-Cueto L.  

Am J Ophthalmol. 2024 Feb:258:223. doi: 10.1016/j.ajo.2023.07.024. Epub 2023 Aug 6. 

15) “Repeatability of Automatic Measurements by an Anterior Segment Swept-Source OCT Biometer in Patients With Keratoconus” 

Abicca I, Schiano Lomoriello D, Gilardi M, Giannini D, Dinu V, Coutinho C, Savini G. 

J Refract Surg. 2024 Jul;40(7):e445-e452. doi: 10.3928/1081597X-20240514-03. Epub 2024 Jul

16) “Comparison of Keratometry and Total Corneal Power, as measured by a swept-source OCT-based optical biometer, for IOL power calculation in Asian eyes.” 

Savini S, Taroni L, Jeon S, Koh K, Hyum S Y, Abulafia A, Lupardi E, Hoffer K J, Moramarco A, Schiano Lomoriello D.  

J Cataract Refract Surg. 2024 Jul 2. doi: 10.1097/j.jcrs.0000000000001515. Online ahead of print. 

17) “Spherical Equivalent Prediction Analysis in IOL Power Calculations Using Eyetemis, A Comprehensive Approach” 

Kan-Tor Y, Abulafia A, Zadok D, Kohnen T, Savini G, Hoffer K J, Yuval B.  

J Cataract Refract Surg. 2024 Jul 2. doi: 10.1097/j.jcrs.0000000000001518. Online ahead of print. 

18) “Reply: Improving Second-Eye Vaulting in Deferred Bilateral Implantable Collamer Lens Surgery” 

Russo A, Filini O, Mertens E, Sheraz M D, Conti L, Carones F, Festa G, Boldini A, Savini G.  

J Refract Surg. 2024 Aug;40(8):e579-e581. doi: 10.3928/1081597X-20240723-01. Epub 2024 Aug 1. 

19) “A Novel Method to Optimize Personal IOL Constants” 

Buonsanti D, Cooke D L, Hoffer K J, Savini G, Lupardi E, Buonsanti J, Aramberri J.  

Am J Ophthalmol. 2024 Aug 31:269:355-361. doi: 10.1016/j.ajo.2024.08.029. Online ahead of print. 

20) “Corneal densitometry measurements comparison between anterior segment OCT and scheimpflug imaging” 

Lupardi E, Moramarco A, Cassini F, Febbraro S, Savini G, Fontana L.  

Int Ophthalmol. 2024 Sep 25;44(1):392. doi: 10.1007/s10792-024-03309-0. 

21) “Salzmann Nodular Degeneration in Ocular and Systemic Diseases” 

Roszkowska A M, Azzaro C, Calderone A, Spinella R, Schiano Lomoriello D, Mencucci R, Wylegala A.  

J Clin Med. 2024 Aug 20;13(16):4900. doi: 10.3390/jcm13164900. 

22) “Agreement between a new fully automatic ocular biometer based on optical low-coherence reflectometry and an optical biometer based on Scheimpflug imaging combined with partial coherence interferometry” 

Ning R, Xu H, Li Yu J, Xu S, Lei C S, Wang Y, Savini G, Schiano Lomoriello D, Zhou X, Huang J. 

BMC Ophthalmol. 2024 Oct 17;24(1):455. doi: 10.1186/s12886-024-03716-y. 

23) “Comparison of intraocular lens power formulas for negative-diopter intraocular lens implantation for high myopia” 

Whang W J, Koh K, Hoffer K J, Schiano Lomoriello D, Lupardi E, Taroni L, Tchah H, Savini G.  

J Cataract Refract Surg. 2024 Oct 16. doi: 10.1097/j.jcrs.00

UR RETINA MEDICA

1) “Rationale and Design of VOYAGER: Long-term Outcomes of Faricimab and Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema in Clinical Practice” 

Guymer R, Bailey C, Chaikitmongkol V, Chakravarthy U, Chaudhary V, Finger R P, Gallego-Pinazo R, Hock Chuan A K, Ishida S, Lovestam-Adrian M, Parravano M, Pinto J D L, Schmitz-Valckenberg S, Sheth V, Souied E H, Chi C G, Gilberg F, Glittenberg C, Scheidl S, Bengus M.  

Ophthalmol Sci. 2023 Dec 3;4(3):100442.doi: 10.1016/j.xops.2023.100442. eCollection 2024 May-Jun. 

2) “Impact of intravitreal anti-VEGF therapy on intraretinal microvascular abnormalities in proliferative diabetic retinopathy” 

De Geronimo D, Parravano M, Sacconi R, Fragiotta S, Giannini D, Costanzo E, Varano M, Querques G. 

Acta Diabetol. 2024 Feb 1. doi: 10.1007/s00592-023-02227-4. Online ahead of print. 

3) “Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success” 

Rabiolo A, Triolo G, Khaliliyeh D, Wook Jin S, Morales E, Ghirardi A, Anand N, Montesano G, Virgili G, Caprioli J, De Cillà S.  

Ophthalmology. 2024 Jan 8:S0161-6420(24)00017-4.doi: 10.1016/j.ophtha.2024.01.008. Online ahead of print. 

4) “Use of the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) questionnaires for clinical decision-making and psychological referral in ophthalmic care: a multicentre observational study” 

Fortini S, Costanzo E, Rellini E, Amore F, Mariotti SP, Varano M, Parravano M, Virgili G, Bandello F, Rizzo S, Turco S.  

BMJ Open. 2024 Jan 18;14(1):e075141.doi: 10.1136/bmjopen-2023-075141. 

5) “ Non-Exudative intraretinal fluid in intermediate age-related macular degeneration” 

Servillo A, Kesim C, Sacconi R, Battist M, Capuano V, Fragiotta S, Querques L, Parravano M, Souied H E, Bandello F, Querques G.  

Retina. 2024 Jan 24.doi: 10.1097/IAE.0000000000004054. Online ahead of print. 

6) “Halo sign on temporal artery ultrasound versus temporal artery biopsy for giant cell arteritis” 

Pouncey A , Yeldham G, Magan T, Lucenteforte E, Jaffer U, Virgili G.  

Cochrane Database Syst Rev. 2024 Feb 7;2(2):CD013199. doi: 10.1002/14651858.CD013199.pub2. 

7) “Diabetic Retinopathy and Quality of Life: A Systematic Review and Meta-Analysis” 

Zayed M G, karsam W, Peto T, Sarayanan P, Virgili G, Presiss D.  

JAMA Ophthalmol. 2024 Feb 1:e236435.doi: 10.1001/jamaophthalmol.2023.6435. Online ahead of print. 

8) “Management of treatment-naïve diabetic macular edema patients: Review of real-world clinical data” 

Boscia F, Veritti D, Iaculli C, Lattanzio R, Freda S, Piergentili B, Varano M.  

Eur J Ophthalmol. 2024 Mar 11:11206721241237069. doi: 10.1177/11206721241237069. Online ahead of print. 

9) “Macular Neovascularization Secondary to Subclinical Angioid Streaks in Age-Related Macular Degeneration: Treatment Response to Anti-VEGF at 2-Year Follow-up” 

Sacconi R, Servillo A, Rissotto F, Bottazzi L, Costanzo E, Polito M S, Tombolini B, Parravano M, Bandello F, Querques G. 

Ophthalmol Ther. 2024 Mar 7. doi: 10.1007/s40123-024-00918-x. Online ahead of print. 

10) “Deep learning for automatic prediction of early activation of treatment naïve non-exudative MNVs in AMD” 

Crincoli E, Catania F, Sacconi R, Ribarich N, Ferrara S, Parravano M, Costanzo E, Querques G. 

Retina. 2024 Mar 14. doi: 10.1097/IAE.0000000000004106. Online ahead of print. 

11) “Phenotypic characterization of predictors for development and progression of geographic atrophy using optical coherence tomography” 

Fragiotta S, Dysli C, Parravano M, Sacconi R, Fantaguzzi F, Servillo A, Severo AA, Tombolini B, Costanzo E, De Geronimo D, Capuano V, Souied E, Bandello F, Querques G. 

Retina. 2024 Mar 11. doi: 10.1097/IAE.0000000000004090. Online ahead of print. 

12) “TENAYA and LUCERNE: 2-Year Results from the Phase 3 nAMD Trials of Faricimab with Treat-and-Extend Dosing in Year 2” 

Khanani AM, Kotecha A, Chang A, Chen SJ, Chen Y, Guymer R, Heier JS, Holz FG, Iida T, Ives JA, Lim JI, Lin H, Michels S, Quezada Ruiz C, Schmidt-Erfurth U, Silverman D, Singh R, Swaminathan B, Willis JR, Tadayoni R; TENAYA and LUCERNE Investigators. 

Ophthalmology. 2024 Feb 19:S0161-6420(24)00134-9. doi: 10.1016/j.ophtha.2024.02.014. Online ahead of print. 

13) “Development and Valuation of a Preference-Weighted Measure in Age-Related Macular Degeneration From the Vision Impairment in Low Luminance Questionnaire-A MACUSTAR Report”. 

Rowen D, Carlton J, Terheyden JH, Finger RP, Wickramasekera N, Brazier J; MACUSTAR Consortium 

Value Health. 2024 Feb 17:S1098-3015(24)00068-8. doi: 10.1016/j.jval.2024.02.001. Online ahead of print. 

14) “Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials” 

Wong TY, Haskova Z, Asik K, Baumal CR, Csaky KG, Eter N, Ives JA, Jaffe GJ, Korobelnik JF, Lin H, Murata T, Ruamviboonsuk P, Schlottmann PG, Seres AI, Silverman D, Sun X, Tang Y, Wells JA, Yoon YH, Wykoff CC; YOSEMITE and RHINE Investigators. 

Ophthalmology. 2023 Dec 28:S0161-6420(23)00933-8. doi: 10.1016/j.ophtha.2023.12.026. Online ahead of print. 

15) “Advancements in Imaging and Therapeutic Options for Dry Age-Related Macular Degeneration and Geographic Atrophy” 

Servillo A, Sacconi R, Oldoni G, Barlocci E, Tombolini B, Battista M, Fantaguzzi F, Rissotto F, Mularoni C, Parravano M, Zucchiatti I, Querques L, Bandello F, Querques G 

Ophthalmol Ther.  2024 Jun 4. doi: 10.1007/s40123-024-00970-7. Online ahead of print

16) Flavonoids with lipase inhibitory activity from lemon squeezing waste: isolation, multispectroscopic and in silico studies” 

Cardullo N, Calcagno D, Pulvirenti L, Sciacca C, Pittalà M G G, Maccarronello A E, Thevenard F, Muccilli V.  

J Sci Food Agric. 2024 May 22. doi: 10.1002/jsfa.13600. Online ahead of print. 

17) “ROBIN: a randomised, double-masked, placebo-controlled Phase IIa study of the AOC3 inhibitor BI 1467335 in diabetic retinopathy” 

Quan Dong Nguyen , Justis P Ehlers , David S Boyer, Xidong Jin ,  Giani A , Michael S Ehrlich  ; ROBIN study investigators 

Eye (Lond). 2024 May 28. doi: 10.1038/s41433-024-03017-0. Online ahead of print. 

18) “Microvascular Changes in treatment-naive nonexudative macular neovascularization complicated by exudation” 

Crincoli E, Catania F, Labbate G, Sacconi R, Ferrara S, Parravano M, Costanzo E, Querques G 

Retina 2024 Oct 1;44(10):1679-1687. doi: 10.1097/IAE.0000000000004194. 

19) “Multimodal imaging in diabetic retinopathy and macular edema: An update about biomarkers” 

Parravano M, Cennamo G, Di Antonio L, Grassi M O, Lupidi M, Rispoli M, Savastano M C, Veritti D, Vujosevic S. 

Surv Ophthalmol. 2024 Nov-Dec;69(6):893-904. doi: 10.1016/j.survophthal.2024.06.006. Epub 2024 Jun 26. 

20) “LeptoVitelliform Maculopathy: delineating a distinct clinical entity from acquired vitelliform lesions” 

Fragiotta S, Parravano M, Sacconi R, Polito M S, Capuano V, Costanzo E, Tombolini B, Souied E H, Bandello F, Querques G.  

Eye (Lond), 2024 Jul 17. doi: 10.1038/s41433-024-03240-9. Online ahead of print.

21) “Multimodal phenotyping of foveal hypoplasia in albinism and albino-like conditions: a pediatric case series with adaptive optics insights” 

Bacci G M, Marziali E, Bargiacchi S, Paques M, Virgili G, Fortunato P, Durand M, Rocca C, Pagliazzi A, Palazzo V, Tiberi L, Vergani D, Landini S, Peron A, Artuso R, Pacini B, Stabile M, Sodi A, Caputo R. 

Sci Rep. 2024 Jul 4;14(1):15454. doi: 10.1038/s41598-024-66326-0. 

22) “Vitelliform Lesions Associated with Leptochoroid and Pseudodrusen” 

Fragiotta S, Parravano M, Corradetti G, Bousquet E, Polito M S, Sacconi R, Capuano V, Costanzo E, Tombolini B, Souied E H, Bandello F, Sadda S R, Sarraf D, Querques G. 

Ophthalmol Retina. 2024 Jul 14:S2468-6530(24)00326-9. doi: 10.1016/j.oret.2024.07.003. Online ahead of print. 

23) “Italian Patient Satisfaction with wAMD Management: SWAN Study Results” 

Peiretti E, Ascardi C, Bandello F, Boscia F, Varano M, Bartezaghi M, De Santi L, Staurenghi G. 

Clin Ophthalmol. 2024 Aug 1:18:2183-2191. doi: 10.2147/OPTH.S468617. eCollection 2024. 

24) “The “triple-layer sign”: an optical coherence tomography signature for the detection of non-exudative macular neovascularization” 

Capuano V, Sacconi R, Miere A, Borrelli E, Amoroso F, Costanzo E, Parravano M, Fragiotta S, Bandello F, Souied E H, Querques G.  

Graefes Arch Clin Exp Ophthalmol.  2024 Jul 23. doi: 10.1007/s00417-024-06585-9. Online ahead of print. 

25) “Cochrane Corner: Anti-vascular endothelial growth factor biosimilar for macular degeneration” 

Su-Hsun Liu, Virgili G.  

Eye (Lond). 2024 Jul 19. doi: 10.1038/s41433-024-03263-2. Online ahead of print.

26) “Utility values and electronic device use in low-vision people attending rehabilitation services: Data from a nation-wide registry in Italy” 

Virgili G, Costanzo E, Biagini I, Parravano M, Di Simone A, Amore F, Tettamanti M, Di Pietro S, Ciaffoni G L, Sato G, Giacomelli G, Bartolomei F. 

PLoS One. 2024 Aug 9;19(8):e0308569. doi: 10.1371/journal.pone.0308569. eCollection 2024. 

27) “A gender-based analysis of retinal microvascular alterations in patients with diabetes mellitus using OCT angiography” 

Vujosevic S, Limoli C, Piccoli G, Costanzo E, Marenzi E, Torti E, Gianni D, Polito M S, Luzi L, Nucci P, Parravano M.  

J Diabetes Complications. 2024 Oct;38(10):108852. doi: 10.1016/j.jdiacomp.2024.108852. Epub 2024 Aug 28. 

28) “Patient Preferences with Anti-Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema: A Multinational Discrete Choice Experiment Study” 

García-Layana A, Chi G C,  Kodjikian L, Parravano M, Chow D, Jackson T L, Danzing C, Paris L P, Mirt M, Henry-Szatkowski M, Lewis H B, Gentile B. 

Ophthalmic Res. 2024 Nov 21:1-17. doi: 10.1159/000541349. Online ahead of print. 

29) “Characterization and topographical analysis of choroidal caverns in young and healthy individuals” 

Fragiotta S, Toto L, Parravano M, Quarta A, Di Noia M, Sacconi R, Dobovsek Divjak D, Rissotto F, Polito M S, Costanzo E, Querques G. 

Eur J Ophthalmol. 2024 Oct 15:11206721241289970. doi: 10.1177/11206721241289970. Online ahead of print. 

30) “Survival and Health Care Burden of Children With Retinoblastoma in Europe” 

Virgili G, Capocaccia R, Botta L, Bennett D, Hadjistilianou T, Innos K, Karim-Kos H, Kuehni C E, Kuhnel U, Mazzini C, Canete Nieto A, Paapsi K, Parravano M, Ronckers C M, Rossi S, Stiller C, Vicini G, Visser O, Gatta G, EUROCARE-6 Working Group. 

JAMA Ophthalmol. 2024 Oct 10;142(11):1062-1070. doi: 10.1001/jamaophthalmol.2024.4140. Online ahead of print. 

31) “Type 3 MNV in AMD: baseline predictors of 3-year macular atrophy development” 

Sacconi R, Forte P, Corradetti G, Costanzo E, Capuano V, Bousquet E, Beretta F, Iannuzzi S, Polito M S, Nicolò M, Parravano M, Souied E, Sarraf E, Sadda S, Bandello F, Querques G. 

Ophthalmol Retina. 2024 Nov 18:S2468-6530(24)00541-4. doi: 10.1016/j.oret.2024.11.011. Online ahead of print. 

32) “Faricimab versus the standard of care for neovascular age-related macular degeneration in Italy: an indirect treatment comparison” 

Galeone C, Turati F, Nicolò M, Parravano M, Vujosevic S, Bianchino L, Sicari E, Lanzetta P. 

Drug Target Insights. 2024 Dec 12:18:105-111. doi: 10.33393/dti.2024.3213. eCollection 2024 Jan-Dec. 

UR RETINA CHIRURGICA

1) Retinal Tectonics after MunkMacular Pucker Surgery: Thickness Changes and En-Face Displacement Recovery. 

Scarinci F, Querzoli G, Cosimi P, Ripandelli G, Romano MR, Cacciamani A, Munk MR, Rossi T. 

Retina. 2024. Jan 1;44(1):102-110.doi: 10.1097/IAE.0000000000003928. 

2) “Three-Dimensional Retinal Displacement Before and After Macular Pucker Surgery” 

Rossi T, Querzoli G, Cosimi P, Ripandelli G, Placentino L,  Steel D H, Romano M R.  

Retina ():10.1097/IAE.0000000000004125, April 4, 2024. | DOI: 10.1097/IAE.0000000000004125 

3) “Tangential Retinal displacement increases after macular pucker surgery: An Apparent Nonsense” 

Rossi T, Querzoli G, Cosimi P, Ripandelli G, Steel D H, Romano M R.  

Retina.  2024 Apr 1;44(4):610-617. doi: 10.1097/IAE.0000000000004001. 

4) “Vitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: conventional internal limiting membrane peeling versus inverted flap” 

Fallico M, Caselgrandi P, Marolo P, Parisi G, Borrelli E, Ricardi F, Gelormnini F, Ceroni L, Reibaldi M, SMALL Study Group 

Eye (Lond).2024 Dec;38(17):3334-3340. doi: 10.1038/s41433-024-03301-z. Epub 2024 Aug 24. 

5) “Vitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: Internal limiting membrane peeling versus no peeling” 

Marolo P, Caselgrandi P, Fallico M, Parisi G, Borrelli E, Ricardi F, Gelormini F, Ceroni L, Reibaldi M, SMALL Study Group. 

Acta Ophthalmol. 2024 Oct 14. doi: 10.1111/aos.16778. Online ahead of print. 

UR ONCOLOGIA E TOSSICOLOGIA OCULARE

1) “Outer Retinal and Choroidal Changes in Adolescents with Long-Lasting Type 1 Diabetes”

Pilotto E, Cosmo E, Torresin T, Coppola M, Joaquin Gutierrez De Rubalcava Doblas, Midena G, Moretti C, Midena E.

J Clin Med. 2023 Dec 30;13(1):229. doi: 10.3390/jcm13010229.

2) “Novel Artificial Intelligence-Based Assessment of Imaging Biomarkers in Full-Thickness Macular Holes: Preliminary Data from a Pivotal Trial”

Mariotti C, Mangoni L, Iorio S, Lombardo V, Fruttini D, Rizzo C, Chhablani J, Midena E, Lupidi M.

J Clin Med. 2024 Jan 22;13(2):628. doi: 10.3390/jcm13020628.

3) “Intravitreal Aflibercept for Neovascular Age-Related Macular Degeneration Beyond One Year of Treatment: AZURE, a Randomized Trial of Treat-and-Extend vs. Fixed Dosing”

Kpdjikian L, Arias Barquet L, Papp A, Kertes P J, Midena E, Ernest J, Silva R, Schmelter T, Niesen T, Leal S.

Adv Ther. 2024 Mar;41(3):1010-1024. doi: 10.1007/s12325-023-02719-3. Epub 2024 Jan 6.

4) “DICER1 Syndrome Discovered Through an Eye Tumor”

Fortarezza F, Midena G, Parrozzani R, Dei Tos A P.

JAMA Ophthalmol. 2024 May 30. doi: 10.1001/jamaophthalmol.2024.1697. Online ahead of print.

5) “Aqueous Humor Cytokines in Idiopathic Epiretinal Membrane: Correlation with Disease Severity”

Torresin T, Greggio A, Frisina R, Motta L, Gius I, Midena G, Midena E.

Diagnostics (Basel). 2024 Aug 16;14(16):1797. doi: 10.3390/diagnostics14161797.

6) “Hyperreflective choroidal foci in diabetic eyes with and without macular edema: Novel insights on diabetic choroidopathy”

Midena G, Danieli L, Pilotto E, Frizziero L, Midena E.

Exp Eye Res. 2024 Oct:247:110020. doi: 10.1016/j.exer.2024.110020. Epub 2024 Aug 8.

7) “Small Hyperreflective Retinal Foci as in vivo imaging feature of resident microglia activation in geographic atrophy”

Pilotto E, Parolini F, Midena G, Cosmo E, Midena E.

Exp Eye Res. 2024 Sep 4:248:110064.doi: 10.1016/j.exer.2024.110064. Online ahead of print.

8) “A deep learning approach to hard exudates detection and disorganization of retinal inner layers identification on OCT images”

Toto L, Romano A, Pavan M, Degl’Innocenti D, Olivotto V, Formenti F, Viggiano P, Midena E, Mastropasqua R.

Sci Rep. 2024 Jul 19;14(1):16652. doi: 10.1038/s41598-024-63844-9.

9) “Chemotherapy induced corneal changes assessed by corneal confocal microscopy. A review”

Cosmo E, Midena G, Parrozzani R, Midena E.

Diagnostics (Basel). 2024 Oct 28;14(21):2399. doi: 10.3390/diagnostics14212399.

10) “Microperimetry Sensitivity Correlates to Structural Macular Changes in Adolescents with Achromatopsia Unlike Other Visual Function Tests”

Cosmo E, Pilotto E, Convento E, Parolini F, Edoardo M.

J Clin Med. 2024 Oct 8;13(19):5968.  doi: 10.3390/jcm13195968

11)The neurovascular retinal involvement in a large population of patients recovered from COVID-19: an OCT and OCT angiography study”

Cosmo E, Frizziero L, Schiavon S, Cattelan AM, Leoni D, Capizzi A, Torresin T, Midena G, Armato Smaniotto Dai Roveri E, Parrozzani R, Midena E

Eye (Lond). 2024 Jun;38(9):1674-1680.doi: 10.1038/s41433-024-02991-9. Epub 2024 Feb 24

UR NEUROFISIOLOGIA DELLA VISIONE E NEUROFTALMOLOGIA

1) “Comment on Lack of reproducibility of resting-state functional MRI findings in migraine with aura” 

Coppola G, Di Renzo A, Parisi V, Serrao M, Caramia F, Petrusic I. 

Cephalalgia. 2024 Jan;44(1):3331024231225186. doi: 10.1177/03331024231225186. 

2)“AFG3L2 and ACO2-Linked Dominant Optic Atrophy: Genotype-Phenotype Characterization Compared to OPA1 Patients” 

Amore G, Romagnoli M, Carbonelli M, Cascavilla ML, De Negri AM, Carta A, Parisi V, Di Renzo A, Schiavi C, Lenzetti C, Zenesini C, Ormanbekova D, Palombo F, Fiorini C, Caporali L, Carelli V, Barboni P, La Morgia C. 

Am J Ophthalmol. 2024 Jan 24:262:114-124. doi: 10.1016/j.ajo.2024.01.011. Online ahead of print. 

3)“Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy” 

Brugger M, Lauri A, Zhen Y, Gramegna LL, Zott B, Sekulić N, Fasano G, Kopajtich R, Cordeddu V, Radio FC, Mancini C, Pizzi S, Paradisi G, Zanni G, Vasco G, Carrozzo R, Palombo F, Tonon C, Lodi R, La Morgia C, Arelin M, Blechschmidt C, Finck T, Sørensen V, Kreiser K, Strobl-Wildemann G, Daum H, Michaelson-Cohen R, Ziccardi L, Zampino G, Prokisch H, Abou Jamra R, Fiorini C, Arzberger T, Winkelmann J, Caporali L, Carelli V, Stenmark H, Tartaglia M, Wagner M.Am J Hum Genet. 2024 Mar 7;111(3):594-613. doi: 10.1016/j.ajhg.2024.02.005. Epub 2024 Feb 28. 

4)“Genotypic and Phenotypic Characterization of a Cohort of Patients Affected by Rod Cyclic Nucleotide Channel-Associated Retinitis Pigmentosa” 

Colombo L, Bonetti G, Maltese P E, Iarossi G, Ziccardi L, Fogagnolo P, De Ruvo V, Murro V, Giorgio D, Falsini B, Placidi G, Martella S, Galantin E, Bertelli M, Rossetti L.  

Ophthalmic Res. 2024;67(1):301-310. doi: 10.1159/000538746. Epub 2024 May 7. 

5)“Retinal Dystrophies Associated With Peripherin-2: Genetic Spectrum and Novel Clinical Observations in 241 Patients” 

Heath Jeffery R, Thompson J A, Lo J, Chelva E S, Armstrong S, Pulido J S, Procopio R, Vincent A L, Bianco L, Battaglia Parodi M, Ziccardi L, Antonelli G, Barbano L, et al.   

Invest Ophthalmol Vis Sci. 2024 May 1;65(5):22. doi: 10.1167/iovs.65.5.22. 

6)“Cortical excitability in patients with migraine with aura and depressive symptoms: a visual evoked potentials study” 

Casillo F, Abagnale C, Sebastianelli G, Di Renzo A, Parisi V, Cioffi E, Serrao M, Di Lorenzo C. 

Confinia Cephalalgica 2024; 1:15764. doi:10.4081/cc.2024.15764;  

 7)“Lack of a direct link between macular cones function and photophobia in interictal migraine” 

Casillo F, Di Renzo A, Sebastianelli G, Abagnale C, Martelli F, Di Lorenzo C, Serrao M, Falsini B, Parisi V, Coppola G.  

Cephalalgia. 2024 Sep;44(9):3331024241276501. doi: 10.1177/03331024241276501. 

8)“Decoding Visual Responses: Insights into Chronic Migraine and Medication Overuse Headache with Electrophysiological Analysis” 

Coppola G, Casillo F, Sebastianelli G, Abagnale C, Di Lorenzo C, Di renzo A, Serrao M, Parisi V. 

J Clin Med 2024 Oct 11;13(20):6070. doi: 10.3390/jcm13206070.  

9)“A 1-month ketogenic diet in patients with migraine gives a clinical beneficial effect associated with increased latency of somatosensory thalamo-cortical activity” 

Abagnale C, Sebastianelli G, Casillo F, Di Renzo A, Parisi V, Cioffi E, Serrao M, Schoenen J, Coppola G, Di Lorenzo C. 

Clin Neurophysiol Pract. 2024 Nov 15:9:292-298. doi: 10.1016/j.cnp.2024.11.002. eCollection 2024. 

 10)“MRI-based analysis of the microstructure of the thalamus and hypothalamus and functional connectivity between cortical networks in episodic cluster headache” 

Abagnale C, Di Renzo A, Giuliani G, Sebastianelli G, Casillo F, Ziccardi L, Parisi V, Di Lorenzo Cm Serrao M, Caramia F, Di Piero V, Coppola G. 

Journal of Headache and Pain. Preprint (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-5240822/v1] 

 11)“Local Dynamic Stability of Trunk During Gait Can Detect Dynamic Imbalance in Subjects with Episodic Migraine” 

Castiglia S F, Sebastianelli G, Abagnale C, Casillo F, Trabassi D, Di Lorenzo A, De Icco R, Tassorelli C, Serrao M, Coppola G. 

Sensors 2024, 24(23), 7627; https://doi.org/10.3390/s24237627 

 12) “Neurophysiological Effects of Withdrawal from Acute Overused Medications in Chronic Migraine with Medication-Overuse Headache” 

Sebastianelli G, Casillo F, Abagnale C, Di Renzo A, Ziccardi L, Parisi V, Di Lorenzo C, Serraio M, Coppola G. 

J Clin Med. 2024 Dec 9;13(23):7491. doi: 10.3390/jcm13237491 

UR LABORATORIO DI RICERCA

1)“Dupilumab‐associated ocular surface disease or atopic keratoconjunctivitis not improved by dupilumab? Upadacitinib may clarify the dilemma: A case report”

Galluzzo M, Tofani L, Spelta S, Talamonti M, Micera A, Bianchi L, Coassin M, Bonini S, Di Zazzo A.

Skin Health and Dis.2024;e354 https://doi.org/10.1002/ski2.354

2) “Breast Cancer Systemic Dryness in Survivorship Clinic”

Grasso A, Di Zazzo A, Altomare V, Coassin M, Orsaria P, Caggiati L, Micera A.

European Journal of Surgical Oncology Volume 50, Issue 2, February 2024, 107490

https://doi.org/10.1016/j.ejso.2023.107490

3) “Editorial for the IJMS Special Issue on “Neurodevelopmental Disorders: From Epigenetic Basis to Therapeutic Perspectives”

Zappella M, Sacco R, Micera A.

Int J Mol Sci. 2024 May 22;25(11):5641. doi: 10.3390/ijms25115641.

4) “Prophylactic Therapy for Long-Term Ocular Discomfort After Cataract Surgery”

Di Zazzo A, Spelta S, Micera A, De Gregorio C, Affatato M, Esposito G, Balzamino B O, Sgrulletta R, Coassin M, Bonini S.

Cornea. 2024 May 17. doi: 10.1097/ICO.0000000000003561. Online ahead of print.

5) “SARS-CoV-2-Related Olfactory Dysfunction: Autopsy Findings, Histopathology, and Evaluation of Viral RNA and ACE2 Expression in Olfactory Bulbs”

Dell’Aquila M, Cafiero C, Micera A, Stigliano E, Ottaiano, P, Benincasa G, Schiavone Bm Guidobaldi L, Santacroce L, Pisconti S, Arena V, Palmirotta R

Biomedicines. 2024 Apr 9;12(4):830. doi: 10.3390/biomedicines12040830

6) “Mast cells and ocular surface: An update review”

Barone V, Scirocco L, Surico PL, Micera A, Cutrupi F, Coassin M, Di Zazzo A.

Exp Eye Res. 2024 Aug:245:109982. doi: 10.1016/j.exer.2024.109982. Epub 2024 Jun 26.

7) “A Functional and Immunologic Point of View on Corneal Endothelial Transplantation: A Systematic Review and Meta-Analysis”

Spelta S, Micera A, Gaudenzi D, Niutta M, Surico PL, De Vincentis A, Coassin M, Di Zazzo A. Clin Med. 2024 Jun 12;13(12):3431. doi: 10.3390/jcm13123431.

LAVORI IN CONDIVISIONE

1)”Detection of insulin oligomeric forms by a novel surface plasmon resonance-diffusion coefficient based approach”

Calcagno D, Perina M L, Zingale G A, Pandino I, Tuccitto N, Olivieri V, Parravano M, Grasso G. 

Protein Sci. 2024 Apr;33(4):e4962.doi: 10.1002/pro.4962. 

2) “Mechanism of Peroxynitrite Interaction with Ferric M. tuberculosis Nitrobindin: A Computational Study”

Messiasi A, Capece L, De Simone G, Coletta M, Ascenzi P, Estrin D A.  

Inorg Chem. 2024 May 27;63(21):9907-9918. doi: 10.1021/acs.inorgchem.4c00833. Epub 2024 May 16  

3) “Carbon dots fluorescence can be used to distinguish isobaric peptide and to monitor protein oligomerization dynamics” 

Zingale GA, Pandino I, Tuccitto N, Dstefano A, Cali F, Calcagno D, Grasso G. 

Methods. 2024 Oct:230:1-8. doi: 10.1016/j.ymeth.2024.07.005. Epub 2024 Jul 20. 

4) “Surface Plasmon Resonance Allows to Correlate Molecular Properties With Diffusion Coefficients of Linear Chain Alcohols” 

Basile GS, Calcagno D, Pandino I, Pietropaolo A, Schifino G, Tuccitto N, Zingale GA, Grasso G. 

Chemistry. 2024 Oct 8;30(56):e202402346. doi: 10.1002/chem.202402346. Epub 2024 Sep 19. 

5)  “Dysfunction and Morphological Involvement of Inner Macular Layers in Glaucoma” 

Parisi V, Ziccardi L, Giammaria S, Barbano L, Tanga L, Michelessi M, Roberti G, Carnevale C, Dell’Aquila C, D’Andrea M, Manni G, Oddone F. 

J Clin Med. 2024 Nov 15;13(22):6882. doi: 10.3390/jcm13226882. 

6) “Expression of Hormones’ Receptors in Human Corneal Endothelium from Fuchs’ Dystrophy: A Possible Gender’ Association” 

De Piano M, Abicca I, Dinu V, Roszkowska A M, Micera A, Schiano Lomoriello D.  

J Clin Med. 2024 Jun 27;13(13):3787. doi: 10.3390/jcm13133787. 

7) “Whole Genome Sequencing Solves an Atypical Form of Bardet-Biedl Syndrome: Identification of Novel Pathogenic Variants of BBS9” 

Stellacci E, Niceta M, Bruselles A, Straface E, Tatti M, Carvetta M, Mancini C, Ceccetti S, Parravano M, Barbano L, Varano M, Trataglia M, Ziccardi L, Cordeddu V. 

Int J Mol Sci. 2024 Jul 30;25(15):8313. doi: 10.3390/ijms25158313. 

8) “Metabolic, Microvascular, and Structural Predictors of Long-Term Functional Changes Evaluated by Multifocal Electroretinogram in Type 1 Diabetes” 

Parravano M, Fragiotta S, Costanzo E, Picconi F, Giorno P, De Geronimo D, Giannini D, Varano M, Parisi V, Ziccardi L.  

Biomedicines. 2024 Nov 15;12(11):2614. doi: 10.3390/biomedicines12112614. 

9) “Leveraging Optical Coherence Tomography and Angiography Artifacts to Identify Clinicopathological Correlates in Macular Disorders” 

Scuderi L, Fragiotta S, Ciancimino C, Mafrici M, Mazzola M, Varano M, Rossi T, Parravano M.  

Photonics 2024, 11(10), 991; https://doi.org/10.3390/photonics11100991 

10) “Retinal Displacement after Idiopathic Macular Hole Surgery: Layer by Layer Analysis” 

Rossi T, Querzoli G, Ripandelli G, Placentino L, Parravano M, Steel DH, Romano MR.  

Retina. 2024 Dec 4. doi: 10.1097/IAE.0000000000004352. Online ahead of print. 

11) “Angiogenic properties of vitreous”

Micera A, Balzamino BO, Cosimi P, Cacciamani A, 

This is an update of G.A. Lutty, anti-angiogenic properties of vitreous. Editors: Darlene A. Dartt. Encyclopedia of the Eye, Academic Press, 2010, pages 112-119, ISBN 9780123742032, https://doi.org/10.1016/B978-0-12-374203-2.00261-X

12) “TLR2 and TLR4 Are Expressed in Epiretinal Membranes: Possible Links with Vitreous Levels of Complement Fragments and DAMP-Related Proteins” Dinice L, Esposito G, Cacciamani A, Balzamino B O, Cosimi P, Cafiero C, Ripandelli G, Micera A.  Int J Mol Sci. 2024 Jul 15;25(14):7732. doi: 10.3390/ijms25147732. 

13) “Retinal Inflammation and Reactive Müller Cells: Neurotrophins’ Release and Neuroprotective Strategies”

Balzamino BO, Cacciamani A, Dinice L, Cecere M, Pesci FR, Ripandelli G, Micera A.

Biology (Basel). 2024 Dec 9;13(12):1030. doi: 10.3390/biology13121030.

14) “Short-Term Culture of Human Hyalocytes Retains Their Initial Phenotype and Displays Their Contraction Abilities” 

Micera A, Balzamino B O, Cosimi P, Esposito G, Ripandelli G, Rossi T. 

Cells 2024 Nov 6;13(22):1837. doi: 10.3390/cells13221837.  

Pubblicazioni 2023

UO GLAUCOMA

1)The use of Surface Plasmon Resonance to study the interactions of proteins involved in conformational diseases: experimental approaches for new therapeutical perspectives.

Zingale G.A., Distefano A, Grasso G.

Curr Med Chem. 2023 Jan 16.doi: 10.2174/0929867330666230116162646. Online ahead of print

2) Carbon dots as a versatile tool to monitor insulin aggregation.

Zingale G.A, Distefano A, Pandino I, Tuccitto N, Oliveri V, Gaeta M, D’Urso A, Arcoria A, Grasso G.

Anal Bioanal Chem. 2023 Apr;415(10):1829-1840. doi: 10.1007/s00216-023-04585-y. Epub 2023 Feb 20.

3)A novel SPR based method for measuring diffusion coefficients: From small molecules to supramolecular aggregates.

Zingale G.A, Pandino I, Distefano A, Tuccitto N, Grasso G.

Bios and Bioelect: X. May 2023,13:100306. doi: 10.1016/j.biosx.2023.100306

4)Insights into the binding of Ag ions with SilE model peptides: an NMR and MS coupled approach.

Zingale G.A., Oliveri V, Grasso G.

Metallomics. 2023 Mar 13;mfad015.doi: 10.1093/mtomcs/mfad015. Online ahead of print.

5) Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study

De Simone G, Di Masi A, Tundo G. R, Coletta M, Ascenzi P.

Int. J. Mol. Sci. 2023, 24(7), 6553; https://doi.org/10.3390/ijms24076553 (registering DOI)

6)The effect of citicoline oral solution on quality of life in patients with glaucoma: the results of an international, multicenter, randomized, placebo-controlled cross-over trial”.

Rossetti L, Goni F, Montesano G, Stalmns I, Topouzis F, Romano D, Galantin E, Delgado-Gonzales N, Giammaria S, Coco G, Vandewalle e, Lemmens S, Giannoulis D, Pappas T, Manni G.

Graefes Arch Clin Exp Ophthalmol . 2023 Jan 14.doi: 10.1007/s00417-022-05947-5. Online ahead of print.

7)Childhood Uveitic Glaucoma: Complex Management in a Fragile Population

Iannucci V, Manni P, Mecarelli G, Giammaria S, Giovannetti F, Lambiase A, Bruscolini A.

Appl. Sci. 2023, 13, 2205. https://doi.org/10.3390/app13042205

8)Physiology-Enhanced Data Analytics to Evaluate the Effect of Altitude on Intraocular Pressure and Ocular Hemodynamics.

Vercellin A.V, Harris A, Belamkar A, Zukerman R, Carichino L, Szopos M, Siesky B, Quaranta L, Bruttini C, Oddone F, Riva I, Guidoboni G.

Photonics 2022 Mar;9(3):158.doi: 10.3390/photonics9030158. Epub 2022 Mar 5.

9)Heterogeneity of Ocular Hemodynamic Biomarkers among Open Angle Glaucoma Patients of African and European Descent.

Siesky B, Harris A, Verticchio Vercellin A, Arciero J, Fry B, Eckert G, Guidoboni G, Oddone F, Antman G.

J Clin Med 2023 Feb 6;12(4):1287.doi: 10.3390/jcm12041287.

10) Anti-vascular endothelial growth factor for neovascular glaucoma.

Rittiphairoj T, Roberti G, Michelessi M.

Cochrane Database Syst Rev. 2023 Apr 3;4(4):CD007920.doi: 10.1002/14651858.CD007920.pub4.

11) How latanoprost changed glaucoma management.

Cordeiro MF, Gandolfi S, Gugleta K, Normando EM, Oddone F.

Acta Ophthalmol. 2023 Jun 23. doi: 10.1111/aos.15725. Online ahead of print.

12)Effectiveness and safety of XEN45 implant over 12 months of follow-up: data from the XEN-Glaucoma Treatment Registry.

Oddone F, Roberti G, Giammaria S, Posarelli C, Ghirelli G, Mastropasqua L, Agnifili L, Micelli Ferrari T, Pace V, Nucci P, Sacchi M, Monsellato G, Altafini R, Scuderi G, Perdicchi A, Uva M, Carnevale C, Covello G, Maglionico MN, Fea A, Figus M.

Eye (Lond). 2023 Jul 6. doi: 10.1038/s41433-023-02642-5. Online ahead of print.PMID: 37414935

13) Ferrous nitrosylated cytochrome c: The unusual strength of the proximal His18-Fe bond.

De Simone G, Monaca SD, Fattibene P, Bocedi A, Coletta M*, Ascenzi P.

JInorgBiochem. 2023Oct;247:112338.doi: 10.1016/j.jinorgbio.2023.112338. Epub 2023 Jul 21

14) Nitric oxide binding to ferrous nitrobindins: A computer simulation investigation

Messias A, Pasquadibisceglie A, Alonso de Armiño D, De Simone G, Polticelli F, Coletta M, Ascenzi P, Estrin DA.

JInorgBiochem.2023Nov;248:112336.doi: 10.1016/j.jinorgbio.2023.112336. Epub 2023 Aug 5

15) A deep learning approach to investigate the filtration bleb functionality after glaucoma surgery: a preliminary study

Mastropasqua L, Agnifili L, Brescia L, Figus M, Posarelli C, Oddone F, Giammaria S, Sacchi M, Pavan M, Degli Innocenti D, Olivotto V, Sensi S L, Mastropasqua R

Graefes Arch Clin Exp Ophthalmol. 2023 Aug 2.doi: 10.1007/s00417-023-06170-6. Online ahead of print.

16) Regional Vessel Density Reduction in the Macula and Optic Nerve Head of Patients with pre-Perimetric Primary open Angle glaucoma.

Verticchio Vercellin A, Siesky B, Antman G, Oddone F, Chang M, Eckert G, Arciero J, Kellner RL, Fry B, Coleman-Belin J, Carnevale C, Harris A.

J Glaucoma. 2023 Sep 13. doi: 10.1097/IJG.0000000000002310. Online ahead of print.

17) MERCURY-3: a randomized comparison of netarsudil/latanoprost and bimatoprost/timolol in open-angle glaucoma and ocular hypertension

Stalmans I, Lim KS, Oddone F, Fichtl M, Belda JI, Hommer A, Laganovska G, Schweitzer C, Voykov B, Zarnowski T, Holló G.

Graefes Arch Clin Exp Ophthalmol. 2023 Aug 24.doi: 10.1007/s00417-023-06192-0. Online ahead of print

18) Ocular blood flow biomarkers may predict long-term glaucoma progression

Verticchio Vercellin A.C, Harris A, Oddone F, Siesky B, Eckert G, Belamkar A, Antman G, Segev F.

Br J Ophthalmol. 2023 Oct 18:bjo-2022-322644. doi: 10.1136/bjo-2022-322644.

19) Spatial Summation in the Glaucomatous Macula: A Link With Retinal Ganglion Cell Damage

Montesano G, Redmond T, Mulholland P J, Garway-Heath D F, Ometto G, Romano D, Antonacci F, Tanga L, Carnevale C, Rossetti L M, Crabb D P, Oddone F.

Invest Ophthalmol Vis Sci. 2023 Nov 1;64(14):36. doi: 10.1167/iovs.64.14.36.

20) Ubiquitin proteasome system and glaucoma: A survey of genetics and molecular biology studies supporting a link with pathogenic and therapeutic relevance

Pandino I , Giammaria S , Zingale G A, Roberti G, Michelessi M, Coletta M, Manni G, Agnifili L, Verticchio Vercellin A , Harris A , Oddone F, Sbardella D,

Mol Aspects Med. 2023 Dec:94:101226. doi: 10.1016/j.mam.2023.101226. Epub 2023 Nov 10.

21)Nitrobindin versus myoglobin: A comparative structural and functional study”

De Simone G, Di Masi A, Pasquadibisceglie A, Coletta A, Sebastiani F, Smulevich G, Coletta M, Ascenzi P.

J Inorg Biochem. 2024 Jan:250:112387.doi: 10.1016/j.jinorgbio.2023.112387. Epub 2023 Oct 1

22) Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects

Boccaccini A, Cavaterra D, Carnevale C, Tanga L, Marini S, Bocedi A, Lacal P M, Manni G, Graziani G, Sbardella D, Tundo G R.

Mol Aspects Med. 2023 Dec:94:101225. doi: 10.1016/j.mam.2023.101225. Epub 2023 Nov 24

23) Heme is pivotal for life

Coletta M, Bolognesi M, Ascenzi P.

J Inorg Biochem. 2024 Jan:250:112423.doi: 10.1016/j.jinorgbio.2023.112423. Epub 2023 Oct 3

24) Managing the ocular surface after glaucoma filtration surgery: an orphan topic

Agnifili L, Figus M, Sacchi M, Oddone F, Villani E, Ferrari G, Posarelli C, Carnevale C, Nucci P, Nubile M, Pastropasqua L.

Graefes Arch Clin Exp Ophthalmol. 2023 Dec 13. doi: 10.1007/s00417-023-06333-5. Online ahead of print.

25)Introductory remarks

Sbardella D, Oddone F, Coletta M.

Mol Aspects Med. 2024 Jan 2:95:101241.doi: 10.1016/j.mam.2023.101241. Online ahead of print.

UO SEGMENTO ANTERIORE CON ANNESSI OCULARI

1)Comprehensive comparisons of ocular biometry: A network-based big data analysis.

Yu J, Wen D, Zhao J, Wang Y, Feng K, Wan T, Savini G, Mcalinden C, Lin X, Niu L, Chen S, Gao Q, Ning R, Jin Y, Zhou X, Huang J.

Eye Vis (Lond). 2022 Dec 10;10(1):1. doi: 10.1186/s40662-022-00320-3.

2)Predictability of the Vault after Implantable Collamer Lens Implantation Using OCT and Artificial Intelligence in Caucasian Eyes.

Russo A, Filini O, Savini G, Festa G, Morescalchi F, Boldini A, Semeraro F.

J Cataract Refract Surg. 2023 Mar 13.doi: 10.1097/j.jcrs.0000000000001182. Online ahead of print.

3)Method to analyze the refractive outcomes of online intraocular lens power formulas.

Lupardi E, Hoffer K.J, Fontana L, Savini G.

J Cataract Refract Surg. 2023 Mar 1;49(3):321-322.doi: 10.1097/j.jcrs.0000000000001122.

4)Accuracy of Nine Formulas to Calculate the Powers of an Extended Depth-of-Focus IOL Using Two SS-OCT Biometers.

Jeon S, Taroni L, Lupardi E, Hoffer K. J, Fontana L, Schiano-Lomoriello D, Kwon H, Savini G.

J Refract Surg. 2023 Mar;39(3):158-164. doi: 10.3928/1081597X-20221221-03. Epub 2023 Mar

5)Agreement between a new optical low coherence reflectometry biometer and an anterior segment optical coherence tomographer.

Wang Y, Wan T, Liu L, Xue Y, Chen X, Savini G, Schiano-Lomoriello D, Zhou X, Yu J, Hiang J.

Eye Vis (Lond). 2023 Feb 25;10(1): 13.doi: 10.1186/s40662-023-00330-9.

6)Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction”.

Ning R, Huang X, Jin Y, Lei C.S, Ma X, Xu S, Xiahou J, Savini G, Schiano-Lomoriello D, Wang X, Zhou X, Huang J.

Ophthalmol Ther. 2023 Mar 2.doi: 10.1007/s40123-023-00693-1. Online ahead of print.

7)Efficacy and safety of UT-DSAEK combined with Carlevale’s sutureless scleral fixation IOL.

Vaiano A.S, Greco A, Greco A, Toro M.E, Leto M.G, Savini G.

Eur J Ophthalmol. 2023 Mar 28;11206721231166558.doi: 10.1177/11206721231166558. Online ahead of print

8)Repeatability and reproducibility of a new fully automatic measurement optical low coherence reflectometry biometer and agreement with swept-source optical coherence tomography-based biometer

Yu J, Seng Lei C, Wan T, Ning R, Xing W, Ma X, Pan H, Savini G, Schiano Lomoriello D, Zhou X, Huang J.

Br J Ophthalmol.2023 May 4;bjo-2023-323268.doi: 10.1136/bjo-2023-323268. Online ahead of print.

9)Rotational Stability of a New Progressive Toric Hydrophobic Intraocular Lens With Gradually Decreasing Cylinder Power.

Savini G, Mularoni A, Destro E, Barboni P, Schiano Lomoriello D.

J Refract Surg. 2023 Jun;39(6):374-380. doi: 10.3928/1081597X-20230424-02. Epub 2023 Jun 1

10) Recommendation for Presbyopia-Correcting Intraocular Lenses: A Delphi Consensus Statement by the ESASO Study Group.

Romano V, Madrid-Costa D, Alfondo J F, Alio J, Allan B, Angunawela R, Auffarth G, Carones F, Khoramnia R, Moore J, Nanavaty M Am Savini G, pagano L, Romano M R, Virgili G, Fernandez-Vega-Cueto L.

Am J Ophthalmol. 2023 May 24; 253:169-180. doi:10.1016/j.ajo.2023.05.002.Online ahead of print.

11)Accuracy of Haigis Formula Using Total Keratometry for IOL Power Calculation in Eyes with Previous Myopic and Hyperopic LASIK and PRK.

Galzignato A, Galvis V, Tello A, Urrea J F, Coutinho C P,Schiano Lomoriello D, Savini G.

Photonics 2023, 10(6), 624; https://doi.org/10.3390/photonics10060624

12) Accuracy of 24 IOL Power Calculation Methods

Oleksiy V Voytsekhivskyy, Kenneth J Hoffer, Larysa Tutchenko, David L Cooke, Giacomo Savini

J Refract Surg. 2023 Apr;39(4):249-256. doi: 10.3928/1081597X-20230131-01. Epub 2023 Apr

13) Double-flanged knotless technique for iris prosthesis and IOL implantation associated with keratoplasty.

Lupardi E, Moramarco A, Iannetta D, Savini G, Fontana L.

Eur J Ophthalmol. 2023 Jun 1;11206721231180324. doi: 10.1177/11206721231180324. Online ahead of print

14) Precision of Corneal Aberrations Measured by a New SD-OCT/Placido Topographer and Its Agreement With a Scheimpflug/Placido Topographer.

Ning R, Huang X, Jin Y, Lei CS, Ma X, Xu S, Xiahou J, Savini G, Schiano-Lomoriello D, Wang X, Zhou X, Huang J.

J Refract Surg. 2023 Jun;39(6): 405-412.doi: 10.3928/1081597X-20230426-02. Epub 2023 Jun 1

15) The Current Burden and Future Solutions for Preoperative Cataract-Refractive Evaluation Diagnostic Devices: A Modified Delphi Study

Henderson BA, Aramberri J, Vann R, Abulafia A, Ainslie-Garcia M, Berdahl J, Ferko N, Gundersen KG, Goto S, Gupta P, Multack S, Persaud E, Raoof D, Savini G, Shammas HJ, Wang L, Wang WZ.

Clin Ophthalmol. 2023 Jul 24;17:2109-2124. doi: 10.2147/OPTH.S412847. eCollection 2023.

16) Reply to the comment on: Recommendation for presbyopia-correcting intraocular lenses: A Delphi consensus statement by the ESASO study group

RomanoV, Madrid-Costa D, Alfonso JF, Alio J, Allan B, Angunawela R, Auffarth G, Carones F, Khoramnia R, Moore J, Nanavaty M A, Savini G, Pagano L, Romano MR, Virgili G, Fernández-Vega-Cueto L.

Am J Ophthalmol. 2023 Aug 5;S0002-9394(23)00303-3. doi: 10.1016/j.ajo.2023.07.024. Online ahead of print

17) One-Year Results of Photorefractive Keratectomy for Myopia and Compound Myopic Astigmatism with 210 nm Wavelength All Solid-State Laser for Refractive Surgery

Roszkowska AM, Tumminello G, Licitra C, Severo AA, Inferrera L, Camellin U, Schiano-Lomoriello D, Aragona P.

J Clin Med. 2023 Jun 27;12(13):4311. doi: 10.3390/jcm12134311

18) Comparison of a New Scheimpflug Camera and Swept-Source Optical Coherence Tomographer for Measurements of Anterior Segment Parameters.

Xiaomin Huang, Xuanqiao Lin, Yizhou Yang, Jinjin Yu, Jiacheng Wang, Kexin Li, Yiran Wang, Giacomo Savini, Domenico Schiano-Lomoriello, Xingtao Zhou, Jinhai Huang

Ophthalmol Ther. 2023 Sep 25. doi: 10.1007/s40123-023-00813-x. Online ahead of print

19) Repeatability and Interobserver Reproducibility of a Swept-Source Optical Coherence Tomography for Measurements of Anterior, Posterior, and Total Corneal Power

Lei S C, Lin X, Ning R, Yu J, Huang X, Li K, Wang Y, Savini G, Schiano Lomoriello D, Zhou X, Huang J.

Ophthalmol Ther. 2023 Dec;12(6):3263-3279.doi: 10.1007/s40123-023-00815-9. Epub 2023 Oct

20) Comment on: Efficacy of segmented axial length and artificial intelligence approaches to intraocular lens power calculation in short eyes

Savini G, Taroni L, Hoffer K J.

J Cataract Refract Surg. 2023 Nov 23.doi: 10.1097/j.jcrs.0000000000001358. Online ahead of print.

21) Comparison of Automated Keratometer and Scheimpflug Tomography for Predicting Refractive Astigmatism in Pseudophakic Eyes

Sun-Na K, Savini G, Whang W-J, Naeser K.

Diagnostics (Basel). 2023 Dec 18;13(24):3687.doi: 10.3390/diagnostics13243687.

22) Evaluation of a New All-in-One Optical Biometer and Comparison With a Validated Swept-source OCT Biometer”.

Li Y, Zou Z, Xu S, Yu J, Ye Q, Li K, Xiao Y, Savini G, Schiano Lomoriello D, Zhou X, Yao M, Huang J.

J Refract Surg. 2023 Dec;39(12):825-830.doi: 10.3928/1081597X-20231018-02. Epub 2023 Dec

23) Dry Eye Para-Inflammation Treatment: Evaluation of a Novel Tear Substitute Containing Hyaluronic Acid and Low-Dose Hydrocortisone

Borroni D, Mazzotta C, Rocha-de-Lossada C, Sanchez-Gonzales J M, Ballesteros-Sanchez A, Garcia-Lorente M, Zamorano-Martin F, Spinelli A, Schiano Lomoriello D, Tedesco G R.

Biomedicines. 2023 Dec 11;11(12):3277.doi: 10.3390/biomedicines11123277

24) Differences between Keratometry and Total Keratometry Measurements in a Large Dataset Obtained with a Modern Swept Source OCT Biometer

Wendelstein J A, Hoffman P C, Hoffer K J, Langenbucher A, Findl O, Ruiss M, Bolz M, Riaz K M, Pantanelli S M, Debellemaniere G, Gatinel D, Cooke D L, Galzignato A, Yeo T K, Seiler T G, Zinkernagel M, Savini G.

Am J Ophthalmol. 2023 Dec 11:S0002-9394(23)00505-6. doi: 10.1016/j.ajo.2023.12.003. Online ahead of print.

25) IOL power formula classifications

Savini G, Hoffer KJ, Kohnen T

Journal of Cataract & Refractive Surgery doi: 10.1097/j.jcrs.0000000000001378

UO RETINA MEDICA

1)Nascent Geographic Atrophy as a Predictor of Type 3 Macular Neovascularization Development.

Sacconi R, Sarraf D, Sadda SR, Freund K.B, Servillo A, Levin Fogel M.M, Costanzo E, Corradetti G, Cabral D, Zur D, Trivizki O, Parravano M, Bandello F, Loewenstein A, Querques G.

Ophthalmol Retina. 2023 Feb 2;S2468-6530(23)00038-6.doi: 10.1016/j.oret.2023.01.019. Online ahead of print.

2)Subretinal Lipid Globules an Early Biomarker of Macular Neovascularization in Eyes with Intermediate Age-Related Macular Degeneration.

Fragiotta S, Parravano M, Costanzo E, De Geronimo D, Varano M, Fernandez-Avellaneda P, Freund K.B.

Retina. 2023 Feb 7.doi: 10.1097/IAE.0000000000003760. Online ahead of print.

3)Prognostic Imaging Biomarkers in Diabetic Macular Edema Eyes Treated with Intravitreal Dexamethasone Implant.

Costanzo E, Giannini D, De Geronimo D, Fragiotta S,Varano M, Parravano M.

J Clin Med. 2023 Feb 6;12(4):1303.doi: 10.3390/jcm12041303.

4)Practical guidance for imaging biomarkers in exudative age-related macular degeneration

Rispoli M, Cennamo G, Antonio LD, Lupidi M, Parravano M, Pellegrini M, Veritti D, Vujosevic S, Savastano MC.

Surv Ophthalmol. 2023 Feb 26;S0039-6257(23)00039-5.doi: 10.1016/j.survophthal.2023.02.004. Online ahead of print.

5) Polytherapy and Multimorbidity Pattern of Users of Anti-VEGF Drugs and Dexamethasone for the Treatment of Age-Related Macular Degeneration and other Vascular Retinopathies in Clinical Practice.

Lucenteforte E, Finocchietti M, Addis A, Tettamanti M, Varano M, Parravano M, Virgili G.

Pharmaceuticals (Basel). 2023 Apr 25;16(5):646. doi: 10.3390/ph16050646.

6) Anti‐vascular endothelial growth factor for diabetic macular oedema: a network meta‐analysis.

Virgili G, Curran K, Lucenteforte E, Peto T, Parravano M.

Cochrane Database of Systematic Reviews 27 June 2023 https://doi.org/10.1002/14651858.CD007419.pub7

7) Progression Biomarkers of Microvascular and Photoreceptor Changes Upon Long-Term Evaluation in Type 1 Diabetes

Fragiotta S, Costanzo E, Picconi F, Giorno P, De Geronimo D, Giannini D, Frontoni S, Varano M, Parravano M.

Invest Ophthalmol Vis Sci. 2023 May 1;64(5):23. doi: 10.1167/iovs.64.5.23

8) Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in Japanese patients with diabetic macular edema: 1-year results from the Japan subgroup of the phase 3 YOSEMITE trial

Shimura Shigehiko Kitano, Nahoko Ogata , Yoshinori Mitamura , Hideyasu Oh , Haruka Ochi , Shino Ohsawa , Akito Hirakata ; YOSEMITE and RHINE Investigators

Cochrane Database of Systematic Reviews 27 June 2023 https://doi.org/10.1002/14651858.CD007419.pub7

9) Artificial intelligence’s role in differentiating the origin for subretinal bleeding in pathological myopia

Crincoli E, Servillo A, Catania F, Sacconi R, Mularoni C, Battista M, Querques L, Parravano M, Costanzo E, Polito MS, Bandello F, Querques G.

Retina. 2023 Jul 21.doi: 10.1097/IAE.0000000000003884. Online ahead of print.

10) Use of electronic devices by people attending vision rehabilitation services in Italy: A study based on the device and aids registry (D.A.Re)

Bartolomei F, Costanzo E, Parravano M, Hogg RE, Lawrenson JG, Falchini E, Di Simone A, Pastore V, Mastrantuono C, Sato G, Amore F, Biagini I, Ciaffoni GL, Tettamanti M, Virgili G.

Eur J Ophthalmol. 2023 Sep 7;11206721231200376. doi: 10.1177/11206721231200376. Online ahead of print.

11) DRCR.net Trials for Diabetic Macular Edema

Parravano M, Costanzo E, Sacconi R, Querques G.

In: Saxena, S., Cheung, G., Lai, T.Y., Sadda, S.R. (eds) Diabetic Macular Edema. Springer, Singapore. pp 69–75.

12) Adverse effects of immunotherapies for multiple sclerosis: a network meta-analysis

Tramacere I, Virgili G, Perduca V, Lucenteforte E, Benedetti M D, Capobussi M, Castellini G, Frau S, Gonzales-Lorenzo M, Featherstone R, Filippini G

^{Cochrane Database Syst Rev . 2023 Nov 30;11(11):CD012186 doi:10.1002/14651858.CD012186.pub2.}

UO RETINA CHIRURGICA

1)Cocaine Abuse as an Immunological Trigger in a Case Diagnosed with Eales Disease

Iannetti L, Scarinci F, Alisi L, Beccia A, Cacciamani A, Saturno MC, Gharbiya M.

Medicina (Kaunas). 2023 Jan 14;59(1):169.doi: 10.3390/medicina59010169.

2)Do Daily Activities Impact Gas Tamponade – Retina Contact after Pars Plana Vitrectomy? A Computational Fluid Dynamics Study.

Rossi T, Badas M.G, Angius Deng F, Querzoli G.

Retina. 2023 Feb 16.doi: 10.1097/IAE.0000000000003750. Online ahead of print.

3)The Short-Term Results of Autologous Platelet-Rich Plasma as an Adjuvant to Re-Intervention in the Treatment of Refractory Full-Thickness Macular Holes.

Buzzi M, Parisi G, Marolo P, Gelormini F, Ferrara M, Raimondi R, Allegrini D, Rossi T, Reibaldi M, Romano M.R.

J Clin Med. 2023 Mar 4;12(5):2050.doi: 10.3390/jcm12052050.

4)Correlation between Morphological Characteristics of Macular Edema and Visual Acuity in Young Patients with Idiopathic Intermediate Uveitis.

Iannetti L, Scarinci F, Alisi L, Armentano M, Sampalmieri Lo, La Cava M, Gharbiya M.

Medicina (Kaunas). 2023 Mar 8;59(3):529.doi: 10.3390/medicina59030529.

5) Phacoemulsification Tip Elongation Under Standardized Resistance: An Objective Measure of Human Crystalline Lens Hardness.

Rossi T, Romano M R, Carotenuto A, Malvasi C, Angelini GB, Rossi A, Telani S, Ripandelli G, Querzoli G.

Transl Vis Sci Technol. 2023 Apr 3;12(4):6.doi: 10.1167/tvst.12.4.6.

6) Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study.

Rossi T, Canepa P, Cavalleri O, Rolandi R, Querzoli G, D’Agostino I, Telani S, Ripandelli G.

Transl Vis Sci Technol2023 Apr 3;12(4):21.doi: 10.1167/tvst.12.4.21.

7) Tips to optimize digital education in ophthalmology: Results from ESASO survey

Ferrara M, Romano V, Iovino C, Kadhim M R, Van Dijk E Hc, Boon Camiel JF, Grassi P, Demirel S, Cartes C, Romano M R, e-LOS Study Group

Eur J Ophthalmol. 2022 Apr 13;33(2):11206721221093187. doi: 10.1177/11206721221093187. Online ahead of print.

8) Retinal Tectonics after Macular Pucker Surgery: Thickness Changes and En-Face Displacement Recovery

Rossi T, Scarinci F, Querzoli G, Cosimi P, Ripandelli G, Romano M, Cacciamani A, Munk M.

Retina 2023. Sep 6.doi: 10.1097/IAE.0000000000003928. Online ahead of print

9) The Role of Subretinal Injection in Ophthalmic Surgery: Therapeutic Agent Delivery and Other Indications.

Tripepi D, Jalil A, Ally N, Buzzi M, Moussa G, Rothschild PR, Rossi T, Ferrara M, Romano MR.

Int J Mol Sci. 2023 Jun 23;24(13):10535. doi: 10.3390/ijms241310535

10)Tangential Retinal Displacement Increases After Macular Pucker Surgery: An Apparent Nonsense

Rossi T, Querzoli G, Cosimi P, Ripandelli G, Steel D H, Romano M R.

Retina 2023 Nov 8. doi: 10.1097/IAE.0000000000004001. Online ahead of print.

11) Can wall shear-stress topology predict proliferative vitreoretinopathy localization following pars plana vitrectomy?

Ledda P G, Rossi T, Badas M G, Querzoli G

J Biomech . 2023 Dec 27:162:111914. doi: 10.1016/j.jbiomech.2023.111914. Online ahead of print.

UO ONCOLOGIA E TOSSICOLOGIA OCULARE

1)Comparison of 50° handheld fundus camera versus ultra-widefield table-top fundus camera for diabetic retinopathy detection and grading.

Midena E, Zennaro L, Lapo C, Torresin T, Midena G, Frizziero L.

Eye (Lond). 2023 Mar 1. doi: 10.1038/s41433-023-02458-3. Online ahead of print.

2)Validation of an Automated Artificial Intelligence Algorithm for the Quantification of Major OCT Parameters in Diabetic Macular Edema.

Midena E, Toto L, Frizziero L, Covello G, Torresin T, Midena G, Danieli L, Pilotto E, Figus M, Mariotti C, Lupidi M.

J Clin Med. 2023 Mar 9;12(6):2134. doi: 10.3390/jcm12062134.

3) The disorganization of retinal inner layers is correlated to Müller cells impairment in diabetic macular edema: an imaging and omic study.

Midena E, Torresin T, Schiavon S, Danieli L, Polo C, Midena G, Frizziero L

Int J Mol Sci. 2023 Jun 1;24(11):9607. doi: 10.3390/ijms24119607.

4) Quantitative and Qualitative Assessments of Retinal Structure with Variable A-Scan Rate Spectralis OCT: Insights into IPL Multilaminarity.

Lupidi M, Mangoni M, Centini C, Pompucci G, Lanzafame L, Danieli L, Fruttini D, Peiretti E, Chhblani J, Mariotti C.

J Clin Med. 2023 Apr 1;12(7):2637. doi: 10.3390/jcm12072637.

5) Artificial intelligence in diabetic retinopathy screening: clinical assessment using handheld fundus camera in a real-life setting.

Lupidi M, Danieli L, Fruttini D, Nicolai M, Lassandro N, Chhablani J, Mariotti C.

Acta Diabetol. 2023 Aug;60(8):1083-1088. doi: 10.1007/s00592-023-02104-0. Epub 2023 May 8

6) Ophthalmological Involvement in Wild-type Transthyretin Amyloidosis: a Multimodal Imaging Study.

Frizziero L, Salvalaggio A, Cosmo E, Cipriani A, Midena E*, Briani C.

J Peripher Nerv Syst. 2023 Aug 8. doi: 10.1111/jns.12589. Online ahead of print

7) Randomized Phase IIb Study of Brimonidine Drug Delivery System Generation 2 for Geographic Atrophy in Age-Related Macular Degeneration.

Freeman W R, Bandello F , Souied E, Guymer RH , Garg SJ, Chen FK, Rich R, Holz FG, Patel SS, Kim K, López FJ; BEACON Study Group

Acta Diabetol. 2023 Aug;60(8):1083-1088. doi: 10.1007/s00592-023-02104-0. Epub 2023 May 8

8) Additional measures of macular function beyond visual acuity

Ríos H A, Lövestam-Adrian M, Plainis S, Tsilimbaris M, Joussen A M, Keegan D, Charles M, Cunha-Vaz J , Midena E

Graefes Arch Clin Exp Ophthalmol . 2023 Nov 8. doi: 10.1007/s00417-023-06272-1. Online ahead of print

UO NEUROFISIOLOGIA DELLA VISIONE E NEUROFTALMOLOGIA

1)Swept-Source Optical Coherence Tomography Thresholds in Differentiating Clinical Outcomes in a Real-World Cohort of Treatment-Naïve Multiple Sclerosis Patients.

U, Kucharczuk J, Tkaczyńska M, Parisi V, Grzybowski A.

Brain Sci. 2023, 13(4), 591; https://doi.org/10.3390/brainsci13040591

2)Retinitis Pigmentosa Associated with EYS Gene Mutations: Disease Severity Staging and Central Retina Atrophy.

Placidi G, Maltese PE, Savastano MC, D’Agostino E, Cestrone V, Bertelli M, Chiurazzi P, Maceroni M, Minnella A.M, Ziccardi L, Parisi V, Rizzo S, Falsini B.

Diagnostics (Basel). 2023 Feb 23;13(5):850.doi: 10.3390/diagnostics13050850.

3)Effects of Botulinum Toxin Type A on the Nociceptive and Lemniscal Somatosensory Systems in Chronic Migraine: An Electrophysiological Study

Sebastianelli G, Casillo F, Di Renzo A, Abagnale C, Cioffi E, Parisi V, Di Lorenzo C, Serrao M, Pierelli F, Schoenen J, Coppola G.

Toxins (Basel). 2023 Jan 14;15(1):76. doi: 10.3390/toxins15010076

4) Morpho-functional changes of retinal ganglion cells and visual pathways in patients with optic disc drusen

Antonelli G, Ziccardi L, Barbano L, Di Renzo A, Parisi V

J Clin Med. 2023 May 12;12(10):3432. doi: 10.3390/jcm12103432.

5) Whole brain surface-based morphometry and tract-based spatial statistics in migraine with aura patients: difference between pure visual and complex auras.

Abagnale C, Di renzo A, Sebastianelli G, Casillo F, Tinelli E, Giuliani G, Tullo M G, Serrao M, Parisi V, Fiorelli M, Caramia F, Schoenen J, Di Piero V, Coppola G.

Front Hum Neurosci. 2023 Apr 18;17:1146302. doi: 10.3389/fnhum.2023.1146302. eCollection 2023.

6) Electrophysiological findings in migraine may reflect abnormal synaptic plasticity mechanisms: A narrative review.

Puledda F, Viganò A, Sebastianelli G, Parisi V, Hsiao FJ, Wang SJ, Chen WT, Massimini M, Coppola G..

Cephalalgia. 2023 Aug;43(8):3331024231195780.doi: 10.1177/03331024231195780.

7)Central sensitization mechanisms in chronic migraine with medication overuse headache: a study of thalamocortical activation and lateral cortical inhibition

Sebastianelli G, Casillo F, Abagnale C, Di renzo A, Cioffi E, Parisi V, Di Lorenzo C, Fazio F, Petricola F, Mattia C, Serrao M, Schoen J, Coppola G.

Cephalalgia . 2023 Oct;43(10):3331024231202240. doi: 10.1177/03331024231202240.

8) Topographical Correlation between Structural and Functional Impairment of the Macular Inner Retinal Layers in Multiple Sclerosis Eyes with a History of Optic Neuropathy

Parisi V, Antonelli G, Barbano L, Gabri C N, Landi D, Mataluni G, Di Renzo A, Buttari F, Marfia G A, Centonze D, Ziccardi L.

J Clin Med . 2023 Nov 19;12(22):7175. doi: 10.3390/jcm12227175

9)Autoantibodies detection in patients affected by autoimmune retinopathies

Ceccarini M R, Medori M C, Dhuli K, Tezzele S, Bonetti G, Micheletti C, Maltese P E, Cecchin S, Donato K , Colombo L, Rossetti L , Staurenghi G, Salvetti A P , Oldani M, Ziccardi L , Marangoni D, Iarossi G, Falsini B, Placidi G, D’Esposito F, Viola F, Nassisi M, Leone G, Cimino L, De Simone L, Mastrofilippo V, Beccari T, Bertelli M.

Eur Rev Med Pharmacol Sci . 2023 Dec;27(6 Suppl):57-63. doi: 10.26355/eurrev_202312_34690

UR LABORATORIO DI RICERCA

1)Oxidative Stress Implication in Retinal Diseases-A Review”

Nebbioso M, Franzone F, Lambiase A, Bonfiglio V, Limoli P.G, Artico M, Taurone S, Vingolo E.M, Greco A, Polimeni A.

Antioxidants (Basel). 2022 Sep 10;11(9):1790. doi: 10.3390/antiox11091790

2) The Cleavage-Specific Tau 12A12mAb Exerts an Anti-Amyloidogenic Action by Modulating the Endocytic and Bioenergetic Pathways in Alzheimer’s Disease Mouse Model

Latina V, Atlante A, Malerba F, La Regina F, Balzamino B O, Micera A, Pignataro A, Stigliano E, Cavallaro S, Calissano P, Amadoro G.

Int J Mol Sci. 2023 Jun 2;24(11):9683.doi: 10.3390/ijms24119683

3) Ocular involvement in Clarkson Disease

Spelta S, Di Zazzo A, Micera A, CervellinM, Coassin M, Bonini S.

Ocul Surf. 2023 Jun 9;29:311-313. doi: 10.1016/j.jtos.2023.06.003. Online ahead of print.

4)Real Life Impact of Dry Eye Disease

Cutrupi F, De Luca A, Di Zazzi A, Micera A, Coassin M, Bonini S.

Semin Ophthalmol. 2023 Apr 24;1-13. doi: 10.1080/08820538.2023.2204931. Online ahead of print.

5)Inflammation and Dry Eye-like Symptoms as Concomitant Manifestations of Laryngo-Pharyngeal Reflux.

Bonini S, Di Zazzo A, Surico p L, Balzamino B O, Lucarelli V, Niutta M, Coassin M, Micera A.

Curr Eye Res. 2023 May 11;1-7. doi: 10.1080/02713683.2023.2207210. Online ahead of print.

6)Ocular Surface Disease as Extraesophageal Gastroesophageal Reflux Disease Manifestation: A Specific Therapeutic Strategy

Di Zazzo A, Micera A*, Surico PL, Balzamino BO, Luccarelli V, Antonini M, Coassin M, Bonini S.

Cornea. 2023 Jul 4.doi: 10.1097/ICO.0000000000003329. Online ahead of print

7)COVID-19 and Alzheimer’s Disease Share Common Neurological and Ophthalmological Manifestations: A Bidirectional Risk in the Post-Pandemic Future

Amadoro G, Latina V, Stigliano E, Micera A

Cells . 2023 Nov 10;12(22):2601. doi: 10.3390/cells12222601.

8) Tissue Remodeling in Ocular Mucous Membrane Pemphigoid

Di Zazzo A, Cutrupi F, De Antoniis M G, Ricci M, Esposito G, Antonini M, Coassin M, Micera A, Perrella A, Bonini S.

Invest Ophthalmol Vis Sci . 2023 Dec 1;64(15):17. doi: 10.1167/iovs.64.15.17.

9) Antiviral effect of high-pressure nasal stimulation

Frari V, Micera A, Bonifacio F, Di Giovanii S, Pierri M, Chiappino G, Greco F, Balazamino B O, Salvinelli F.

Eur Rev Med Pharmacol Sci 2023 Oct;27(19):9257-9266. doi:10.26355/eurrev_202310_33953.

10)Intranasal self-administration of high-pressure physiological saline isotonic solution ameliorates dry eye symptoms and tear film composition: a pilot study

Salvinelli F, Gualdi L, Bonifacio F, Gualdi F, Frari V, Balazamino B O, Micera A.

Eur Rev Med Pharmacol Sci . 2023 Oct;27(20):10069-10075 doi:10.26355/eurrev_202310_34187

LAVORI IN CONDIVISIONE

1) Biomarkers’ signature in aqueous humor mirrors lens epithelial cell activation: new biomolecular aspects from cataractogenic myopia

De Piano M, Cacciamani A, Balzamino BO, Scarinci F, Cosimi P, Cafiero C, Ripandelli G and Micera A*

Biomolecules 2023, 13(9), 1328; https://doi.org/10.3390/biom13091328

2) The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design

Tundo G R, Grasso G, Persico M, Tkachuk O, Bellia F, Bocedi A, Marini S, Parravano M, Graziani G, Fattorusso C, Sbardella D,

Biomolecules. 2023 Oct 7;13(10):1492.doi: 10.3390/biom13101492.

3)Expression of GNAQ, BAP1, SF3B1, and EIF1AX Proteins in the Aqueous Humor of Eyes Affected by Uveal Melanoma”

Midena G, Parrozzani R, Frizziero L, Esposito G, Micera A, Midena E.

Invest Ophthalmol Vis Sci. 2024 Jan 2;65(1):15.doi: 10.1167/iovs.65.1.15.

4) The ideal intravitreal injection setting: office, ambulatory surgery room or operating theatre? A narrative review and international surve

Veritti D, Sarao V, Chhablani J, Loewenstein A, Lanzetta P, Società Italiana delle Retina (SIR) Study Group, Intravitreal Injection Setting Study Group (I2SG)

Graefes Arch Clin Exp Ophthalmol. 2023 Nov;261(11):3299-3306.doi: 10.1007/s00417-023-06108-y. Epub 2023 May 18.

Pubblicazioni 2004-1994

2004

1)Lambiase A, Micera A, Sgrulletta R, Bonini S, Bonini S.

Nerve growth factor and the immune system: old and new concepts in the cross-talk between immune and resident cells during pathophysiological conditions.

Curr Opin Allergy Clin Immunol. 2004 Oct;4(5):425-430.

2)Bonini S, Coassin M, Aronni S, Lambiase A.

Vernal keratoconjunctivitis.

Eye.2004;18:345-351.

3)Manni G, Centofanti M, Sacchetti M, Oddone F, Bonini S, Parravano M, Bucci MG.

Demographic and clinical factors associated with development of brimonidine tartrate 0.2%-induced ocular allergy.

J Glaucoma. 2004;13:163-167. 

4)Ripandelli G, Parisi V, Friberg TR, Coppe AM, Scassa C, Stirpe M.

Retinal detachment associated with macular hole in high myopia: using the vitreous anatomy to optimize the surgical approach.

Ophthalmology. 2004;111:726-731.

5)Menchini U, Virgili G, Introini U, Bandello F, Ambesi-Impiombato M, Pece A, Parodi MB, Giacomelli G, Capobianco B, Varano M, Brancato R.

Outcome of choroidal neovascularization in angioid streaks after photodynamic therapy.

Retina. 2004 Oct;24(5):763-771.

6)Micera A, Lambiase A, Aloe L, Bonini S, Levi-Schaffer F, Bonini S.

Nerve growth factor involvement in the visual system: implications in allergic and neurodegenerative diseases.

Cytokine Growth Factor Rev. 2004;15:411-7.

7)Parisi V, Manni GL, Olzi D, Oddone F, Coppola G, Bucci MG.

Impaired neural conduction in crossed visual pathways in patients with ocular hypertension.

Eur J Ophthalmol. 2004;14:486-94.

8)Midena E, Radin PP, Pilotto E, Ghirlando A, Convento E, Varano M.

Fixation pattern and macular sensitivity in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. A microperimetry study.

Semin Ophthalmol. 2004;19:55-61.

9)Manni G, Centofanti M, Parravano M, Oddone F, Bucci M.

A 6-month randomized clinical trial of bimatoprost 0.03% versus the association of timolol 0.5% and latanoprost 0.005% in glaucomatous patients.

Graefes Arch Clin Exp Ophthalmol. 2004 Sep;242(9):767-770.

2003

1)Parisi V, Pierelli F, Fattapposta F, Bianco F, Parisi L, Restuccia R, Malandrini A, Ferrari M, Carrera P.

Early visual function impairment in CADASIL.

Neurology. 2003 Jun 24;60(12):2008-10. 

2)Parisi V.

Correlation between morphological and functional retinal impairment in patients affected by ocular hypertension, glaucoma, demyelinating optic neuritis and Alzheimer’s disease.

Semin Ophthalmol. 2003 Jun;18(2):50-7. Review. 

3)Bonini S, Lambiase A, Sacchetti M, Bonini S.

Cytokines in ocular allergy.

Int Ophthalmol Clin. 2003 Winter;43(1):27-32. Review. 

4)D’Angelo G, Lambiase A, Cortes M, Sgrulletta R, Pasqualetti R, Lamagna A, Bonini S.

Preservative-free diclofenac sodium 0.1% for vernal keratoconjunctivitis.

Graefes Arch Clin Exp Ophthalmol. 2003 Mar;241(3):192-5. Epub 2003 Feb 15.

5)Lambiase A, Bonini S, Rasi G, Coassin M, Bruscolini A, Bonini S.

Montelukast, a leukotriene receptor antagonist, in vernal keratoconjunctivitis associated with asthma.

Arch Ophthalmol. 2003 May;121(5):615-20.

6)Bonini S, Lambiase A, Sgrulletta R, Bonini S.

Allergic chronic inflammation of the ocular surface in vernal keratoconjunctivitis.

Curr Opin Allergy Clin Immunol. 2003 Oct;3(5):381-7. 

7)Bonini S, Rama P, Olzi D, Lambiase A.

Neurotrophic keratitis.

Eye. 2003 Nov;17(8):989-95. 

8)Groneberg DA, Bielory L, Fischer A, Bonini S, Wahn U.

Animal models of allergic and inflammatory conjunctivitis.

Allergy. 2003 Nov;58(11):1101-13.

9)Lambiase A, Manni L, Rama P, Bonini S.

Clinical application of nerve growth factor on human corneal ulcer.

Arch Ital Biol. 2003 Mar;141(2-3):141-8.

10)Landi F, Aloe L, Russo A, Cesari M, Onder G, Bonini S, Carbonin PU, Bernabei R.

Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial.

Ann Intern Med. 2003 Oct 21;139(8):635-41.

11)Ghinelli E, Aloe L, Cortes M, Micera A, Lambiase A, Bonini S.

Nerve growth factor (NGF) and lenses: effects of NGF in an in vitro rat model of cataract.

Graefes Arch Clin Exp Ophthalmol. 2003 Oct;241(10):845-51. Epub 2003 Sep 09.

12)Coppe AM, Ripandelli G.

Optical coherence tomography in the evaluation of vitreoretinal disorders of the macula in highly myopic eyes.

Semin Ophthalmol. 2003 Jun;18(2):85-8.

13)Ripandelli G, Scassa C, Parisi V, Gazzaniga D, D’Amico DJ, Stirpe M.

Cataract surgery as a risk factor for retinal detachment in very highly myopic eyes.

Ophthalmology. 2003 Dec;110(12):2355-61. 

14)Midena E, Pilotto E, de Belvis V, Zaltron S, Doro D, Segato T, Piermarocchi S.

Choroidal vascular changes after transpupillary thermotherapy for choroidal melanoma.

Ophthalmology. 2003 Nov;110(11):2216-22.

2002

1)Parisi V, Canu D, Iarossi G, Olzi D, Falsini B.

Altered recovery of macular function after bleaching in Stargardt’s disease-fundus flavimaculatus: pattern VEP evidence.

Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2741-8. 

2)Centofanti M, Migliardi R, Bonini S, Manni G, Bucci MG, Pesavento CB, Amin CS, Harris A.

Pulsatile ocular blood flow during pregnancy.

Eur J Ophthalmol. 2002 Jul-Aug;12(4):276-80.

3)Parisi V, Manni GL, Gregori D, Olzi D, Meconi S, Coppola G, Scipioni M, Bucci MG.

Crossed and uncrossed visual pathways are impaired differently in open angle glaucoma patients.

Acta Ophthalmol Scand. 2002 Oct;80 Suppl 236:50-51. 

4)Centofanti M, Manni GL, Migliardi R, Zarfati D, Lorenzano D, Scipioni M, Harris A, Bucci MG.

Influence of pregnancy on ocular blood flow.

Acta Ophthalmol Scand. 2002 Oct;80 Suppl 236:52-53. 

5)Varano M, Scassa C, Capaldo N, Sciamanna M, Parisi V.

Development of macular pseudoholes: a 36-month period of follow-up.

Retina. 2002 Aug;22(4):435-42.

2001

1)Parisi V, Restuccia R, Fattapposta F, Mina C, Bucci MG, Pierelli F.

Morphological and functional retinal impairment in Alzheimer’s disease patients.

Clin Neurophysiol. 2001 Oct;112(10):1860-7.

2)Parisi V, Manni G, Centofanti M, Gandolfi SA, Olzi D, Bucci MG.

Correlation between optical coherence tomography, pattern electroretinogram, and visual evoked potentials in open-angle glaucoma patients.

Ophthalmology. 2001 May;108(5):905-12.

3)Parisi V, Uccioli L.

Visual electrophysiological responses in persons with type 1 diabetes.

Diabetes Metab Res Rev. 2001 Jan-Feb;17(1):12-8. Review.

4)Parisi V.

Electrophysiological evaluation of the macular cone adaptation: VEP after photostress. A review.

Doc Ophthalmol. 2001 May;102(3):251-62.

5)Parisi V.

Impaired visual function in glaucoma.

Clin Neurophysiol. 2001 Feb;112(2):351-8. 

6)Genuardi M, Klutz M, Devriendt K, Caruso D, Stirpe M, Lohmann DR.

Multiple lipomas linked to an RB1 gene mutation in a large pedigree with low penetrance retinoblastoma.

Eur J Hum Genet. 2001 Sep;9(9):690-4.

7)Ripandelli G, Coppe AM, Fedeli R, Parisi V, D’Amico DJ, Stirpe M.

Evaluation of primary surgical procedures for retinal detachment with macular hole in highly myopic eyes: a randomized comparison of vitrectomy versus posterior episcleral buckling surgery.

Ophthalmology. 2001 Dec;108(12):2258-64; discussion 2265.  

2000

1)Lambiase A, Bonini S, Aloe L, Rama P, Bonini S.

Anti-inflammatory and healing properties of nerve growth factor in immune corneal ulcers with stromal melting.

Arch Ophthalmol. 2000 Oct;118(10):1446-9. No abstract available.

2)Parisi V, Pierelli F, Malandrini A, Carrera P, Olzi D, Gregori D, Restuccia R, Parisi L. 

Visual electrophysiological responses in subjects with cerebral autosomal arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Clin Neurophysiol. 2000 Sep;111(9):1582-8.

3)Centofanti M, Manni G, Gregori D, Cocco F, Lorenzano D, Bucci MG.

Comparative acute effects of brimonidine 0.2% versus dorzolamide 2% combined with beta-blockers in glaucoma.

Graefes Arch Clin Exp Ophthalmol. 2000 Apr;238(4):302-5.

4)Centofanti M, Bonini S, Manni G, Guinetti-Neuschuler C, Bucci MG, Harris A.

Do sex and hormonal status influence choroidal circulation?

Br J Ophthalmol. 2000 Jul;84(7):786-7.

5)Centofanti M, Zarfati D, Manni GL, Bonini S, Migliardi R, Oddone F, Harris A, Bucci MG.

The influence of oestrogen on the pulsatile ocular blood flow.

Acta Ophthalmol Scand Suppl. 2000;78(232):38-9. No abstract available.

6)Lesnoni G, Rossi T, Nistri A, Boccassini B.

Long-term prognosis after removal of silicone oil.

Eur J Ophthalmol. 2000 Jan-Mar;10(1):60-5. 

7)Varano M, Scassa C, Ripandelli G, Billi B, Stirpe M.

Occult choroidal hemangioma revealed after vitrectomy for macular pucker. Retina.

2000; 20(3):306-9. No abstract available.

8)Bonini S, Lambiase A, Rama P, Caprioglio G, Aloe L.

Topical treatment with nerve growth factor for neurotrophic keratitis

Ophthalmology. 2000;107:1347-53.

1999

1)Bernabei R, Landi F, Bonini S, Onder G, Lambiase A, Pola R, Aloe L.

Effect of topical application of nerve-growth factor on pressure ulcers.

Lancet. 1999 Jul 24;354(9175):307. 

2)Bonini S, Lambiase A, Juhas T, Bonini S.

Allergic conjunctivitis.

Dev Ophthalmol. 1999;30:54-61. Review. No abstract available. 

3)Bonini S, Lambiase A, Bonini S.

Genetics of ocular allergy.

Acta Ophthalmol Scand Suppl. 1999;(228):31-2. Review. No abstract available. 

4)Lambiase A, Rama P, Aloe L, Bonini S.

Management of neurotrophic keratopathy.

Curr Opin Ophthalmol. 1999 Aug;10(4):270-6. Review.

5)Parisi V, Manni G, Spadaro M, Colacino G, Restuccia R, Marchi S, Bucci MG, Pierelli F.

Correlation between morphological and functional retinal impairment in multiple sclerosis patients.

Invest Ophthalmol Vis Sci. 1999 Oct;40(11):2520-7.

6)Parisi V, Manni G, Colacino G, Bucci MG.

Cytidine-5′-diphosphocholine (citicoline) improves retinal and cortical responses in patients with glaucoma.

Ophthalmology. 1999 Jun;106(6):1126-34.

7)Parisi V, Manni G, Gandolfi SA, Centofanti M, Colacino G, Bucci MG.

Visual function correlates with nerve fiber layer thickness in eyes affected by ocular hypertension.

Invest Ophthalmol Vis Sci. 1999 Jul;40(8):1828-33. 

8)Parisi V, Colacino G, Milazzo G, Scuderi AC, Manni G.

Effects of nicergoline on the retinal and cortical electrophysiological responses in glaucoma patients: a preliminary open study.

Pharmacol Res. 1999 Sep;40(3):249-55. 

9)Lesnoni G, Rossi T, Nistri A, Boccassini B.

Nanophthalmic uveal effusion syndrome after prophylactic laser treatment.

Eur J Ophthalmol. 1999 Oct-Dec;9(4):315-8. 

10)Ripandelli G, Coppe AM, Bonini S, Giannini R, Curci S, Costi E, Stirpe M.

Morphological evaluation of full-thickness idiopathic macular holes by optical coherence tomography.

Eur J Ophthalmol. 1999 Jul-Sep;9(3):212-6.

11)Varano M, Scassa C, Ripandelli G, Capaldo N.

New diagnostic tools for macular edema.

Doc Ophthalmol. 1999; 97(3-4):373-9. No abstract available.

1998

1)Lambiase A, Rama P, Bonini S, Caprioglio G, Aloe L.

Topical treatment with nerve growth factor for corneal neurotrophic ulcers.

N Engl J Med. 1998 Apr 23;338(17):1174-80.

2)Solomon A, Aloe L, Pe’er J, Frucht-Pery J, Bonini S, Bonini S, Levi-Schaffer F.

Nerve growth factor is preformed in and activates human peripheral blood eosinophils.

J Allergy Clin Immunol. 1998 Sep;102(3):454-60.

3)Parisi V, Pierelli F, Restuccia R, Spadaro M, Parisi L, Colacino G, Bucci MG.

Impaired VEP after photostress response in multiple sclerosis patients previously affected by optic neuritis.

Electroencephalogr Clin Neurophysiol. 1998 Jan;108(1):73-9. 

4)Parisi V, Uccioli L, Parisi L, Colacino G, Manni G, Menzinger G, Bucci MG.

Neural conduction in visual pathways in newly-diagnosed IDDM patients.

Electroencephalogr Clin Neurophysiol. 1998 Sep;108(5):490-6.

5)Ripandelli G, Coppe AM, Capaldo A, Stirpe M.

Optical coherence tomography.

Semin Ophthalmol. 1998 Dec;13(4):199-202. Review.

6)Varano M, Scassa C. Scanning laser ophthalmoscope microperimetry.

Semin Ophthalmol. 1998 Dec;13(4):203-9.

1997

1)Bonini S, Schiavone M, Bonini S, Magrini L, Lischetti P, Lambiase A, Bucci MG.

Efficacy of lodoxamide eye drops on mast cells and eosinophils after allergen challenge in allergic conjunctivitis.

Ophthalmology. 1997 May;104(5):849-53.

2)Bonini S, Magrini L, Rotiroti G, Lambiase A, Tomassini M, Rumi C, Bonini S.

The eosinophil and the eye.

Allergy. 1997;52(34 Suppl):44-7. Review.

3)Lambiase A, Bonini S, Micera A, Tirassa P, Magrini L, Bonini S, Aloe L.

Increased plasma levels of substance P in vernal keratoconjunctivitis.

Invest Ophthalmol Vis Sci. 1997 Sep;38(10):2161-4. 

4)Lambiase A, Bracci-Laudiero L, Bonini S, Bonini S, Starace G, D’Elios MM, De Carli M, Aloe L.

Human CD4+ T cell clones produce and release nerve growth factor and express high-affinity nerve growth factor receptors.

J Allergy Clin Immunol. 1997 Sep;100(3):408-14.

5)Billi B, Lesnoni G, Audisio P, Giuliano MA, Rossi T, Costi E, Stirpe M.

Pars plana vitrectomy for retinal detachment due to internal posterior ophthalmomyiasis after cataract extraction.

Graefes Arch Clin Exp Ophthalmol. 1997 Apr;235(4):255-8. 

7)Parisi V, Pernini C, Guinetti C, Neuschuler R, Bucci MG.

Electrophysiological assessment of visual pathways in glaucoma.

Eur J Ophthalmol. 1997 Jul-Sep;7(3):229-35. 

8)Centofanti M, Manni GL, Napoli D, Bucci MG.

Comparative effects of intraocular pressure between systemic and topical carbonic anhydrase inhibitors: a clinical masked, cross-over study.

Pharmacol Res. 1997 May;35(5):481-5.

9)Lesnoni G, Billi B, Rossi T, Stirpe M.

The use of panoramic viewing system in relaxing retinotomy and retinectomy.

Retina. 1997;17(3):186-90.

10)Parisi V, Uccioli L, Monticone G, Parisi L, Manni G, Ippoliti D, Menzinger G, Bucci MG.

Electrophysiological assessment of visual function in IDDM patients.

Electroencephalogr Clin Neurophysiol. 1997 Mar;104(2):171-9. 

11)Ripandelli G, Coppe AM, Falsini B, Fedeli R, Stirpe M.

Complications in the removal of the posterior vitreous cortex.

Dev Ophthalmol. 1997; 29:55-60. No abstract available.

12)Varano M, Billi B, Scassa C, Rossi T, Stirpe M.

Scanning laser ophthalmoscopy in the early diagnosis of vitreoretinal interface syndrome.

Retina. 1997;17(4):300-5.

1996

1)Billi B, Lesnoni G, Giuliano M, Rossi T, Stirpe M.

Post-traumatic macular break associated to congenital optic disc pit and pre-existing sensory macular detachment.

Int Ophthalmol. 1996-97;20(5):269-72. 

2)Ripandelli G, Billi B, Fedeli R, Stirpe M.

Retinal detachment after clear lens extraction in 41 eyes with high axial myopia.

Retina. 1996;16(1):3-6. 

3)Rossi L, Sacerdoti D, Billi B, Lesnoni G, Orciuolo M, Rossi T, Sacerdoti D, Bertollini L.

Automatic speech recognition in vitreo-retinal surgery. A project for a prototypal computer-based voice-controlled vitrectomy machine.

Eur J Ophthalmol. 1996 Oct-Dec;6(4):454-9. 

4)Stirpe M, Heimann K.

Vitreous changes and retinal detachment in highly myopic eyes.

Eur J Ophthalmol. 1996 Jan-Mar;6(1):50-8.

1995

1)Billi B, Lesnoni G, Scassa C, Giuliano MA, Coppe AM, Rossi T.

Copper intraocular foreign body: diagnosis and treatment.

Eur J Ophthalmol. 1995 Oct-Dec;5(4):235-9.

2)Lesnoni G, Coppe AM, Manni G, Billi B, Stirpe M.

Analgesic effect of topical diclofenac versus betamethasone after posterior segment surgery.

Retina. 1995;15(1):34-6

1994

1)Stirpe M, Bucci MG, Quaranta L.

Surgical avulsion of the iris to treat selected cases of neovascular glaucoma.

Ger J Ophthalmol. 1994 Mar;3(2):79-83.

Pubblicazioni 2005

DIAGNOSI PRECOCE E VALUTAZIONE DEL DANNO MORFO-FUNZIONALE NEL GLAUCOMA 

1)Bucci MG, Centofanti M, Oddone F, Parravano M, Balacco Gabrieli C, Pecori-Giraldi J, Librando A, Paone E, Bores LD.

Pilot study to evacuate the efficacy and safety of pneumatic trabeculoplasty in glaucoma and ocular hypertension.

Eur. J Ophthalmol. May-June 2005; 15(3):347-352.

2)Manni G, Centofanti M, Oddone F, Parravano M, Bucci MG.

Interlukin – 1 ß tear concentration in glaucomatous and ocular hyopertensive patients treated with preservative – free non selective beta-blockers.

Am J Ophthalmol. 2005 Jan; 139 (1):72–77.

3)Centofanti M, Oddone F, Parravano M, Gualdi L, Bucci MG, Manni G.

Corneal birefringence changes after laser assisted in situ keratomileusis and their influence on retinal nerve fiber layer thickness measurement by means of scanning laser polarimetry.

Br. J. Ophth. 2005 June; 89(6):689-693.

4)Parisi V.

Electrophysiological assessment of glaucomatous visual dysfunction during treatment with citicoline: a study of 8 years of follow-up.

Doc Ophthalmol. 2005; Jan;110(1):91-102.

STUDIO DEI MECCANISMI FISIOPATOLOGICI DELLA SUPERFICIE OCULARE IN CORSO DI PATOLOGIE ALLERGICHE, AUTOIMMUNI E DEGENERATIVE.POSSIBILE RUOLO TERAPEUTICO DEL NERVE GROWTH FACTOR E DEGLI AGONISTI DEI TOLL-LIKE RECEPTORS

1)Coassin M, Lambiase A, Micera A, Tirassa P, Aloe L, Bonini S.

Nerve growth factor modulates in vitro the expression and release of TGF-ß1 by amniotic membrane.

Graefes Arch Clin Exp Ophthalmol 2005; 13: 1-7.

2)Coassin M, Lambiase A, Costa N, De Gregorio A, Sgrulletta R, Sacchetti M, Aloe L, Bonini S.

Efficacy of topical nerve growth factor treatment in dogs affected by dry eye.

Graefe’s Arch. Exp Ophthalmol. 2005; 243:151 – 155.

3)Cortes M, Lambiase A, Sacchetti M, Aronni S, Bonini S.

Limbal Stem Cell Deficiency Associated with LADD Sindrome Arch.

Ophth. 2005; May 123 (5): 691 – 694.

4)Lambiase A, Merlo D, Mollinari C, Bonini P, Rinaldi AM, Amato MD, Micera A, Coassin M, Rama P, Bonini S, Garaci E.

Molecular basis for keratoconus: Llack of TrkA expression and its transcriptional repression by Sp3.

Proc Natl Acad Sci U S A. 2005; Nov 15;102(46):16795-800. 

5)Lambiase A, Sacchetti M, Sgrulletta R, Coassin M, Bonini S.

Amniotic membrane transplantation associated with conjunctival peritomy in the management of Mooren’s ulcer: a case report Eur J Ophthalmol.

2005 Mar-Apr;15(2):274-276. 

6)Lambiase A, Tirassa P, Micera A, Aloe L, Bonini S.

Pharmacokinetics of conjunctivally applied nerve growth factor in the retina and optic nerve of adults rats.

Invest Ophthalmol Vis Sci, 2005; 46:3800-3806.

7)Lenzi L, Coassin M, Lambiase A, Bonini S, Amendola T, Aloe L.

Effect of exogenous administration of nerve growth factor in the retina of rats with inherited retinitis pigmentosa.

Vision Res. 2005 Jun;45(12):1491-1500. 

8)Micera A, Puxeddu I, Lambiase A, Antonelli A, Bonini S, Bonini S, Aloe L, Pe’er J, Levi-Schaffer F.

The pro-fibrogenic effect of NGF of Conjunctival Fibroblasts is mediated by transforming Growth Factor-ß.

Clin Exp Allergy 2005; 35(5):650-656.

9)Sacchetti M, Lambiase A, Cortes M, Sgrulletta R, Bonini S, Merlo D, Bonini S.

Clinical and cytological findings in limbal stem cell deficiency

Graefes Arch Clin Exp Ophthalmol. 2005; 243:870-987.

10)Bonini S, Micera A, Iovieno A, Lambiase A, Bonini S.

Expression of Toll-like receptors in healthy and allergic conjunctiva.

Ophthalmology. 2005 Sep;112(9):1528-1534.

11)Micera A, Stampachiacchiere B, Aronni S, dos Santos MS, Lambiase A.

Toll-like receptors and the eye.

Curr Op Allergy Clin Immunol 2005: Oct;5(5):451-458.

DIAGNOSI PRECOCE E VALUTAZIONE DI FATTORI DI RISCHIO MORFOLOGICI NELLA MIOPIA ELEVATA

1)Coppe AM, Ripandelli G, Parisi V, Varano M, Stirpe M.

Prevalence of Asymptomatic Macular Holes in Highly Myopic Eyes.

Ophthalmology. 2005; 112:2103-2109.

DIAGNOSI PRECOCE E VALUTAZIONE DEL DANNO MORFO-FUNZIONALE E TERAPIA DELLE MACULOPATIE

1)Varano M, Parisi V, Tedeschi M, Sciamanna M, Gallinaro G, Capaldo N, Catalano S, Pascarella A.

Macular function after PDT in myopic maculopathy: Psychophysical and Electrophysiological Evaluation.

Invest Ophthalmol. Vis. Sc. 2005 Apr; 46 (4):1453 – 1462.

2)Varano M, Scassa C, Ducoli P, Terrana M, Calabro’ F, Parisi V.

Visual acuity and macular sensitivity in myopic eyes before and after in situ Keratomeleusis (LASIK) procedure.

Eur J Ophthalmol. 2005; 15:695-701.

3)Testa F, Marini V, Rossi S, Interlandi E, Nesti A, Rinaldi M, Varano M, Garre C, Simonelli F.

A novel mutation in the RDS gene in an Italian family with pattern dystrophy.

Br J Ophthalmol. 2005 Aug;89(8):1066-1068.

4)Giansanti F, Virgili G, Varano M, Tedeschi M, Rapizzi E, Giacomelli G, Menchini U.

Photodynamic therapy for choroidal neovascularization in pediatric patients. Retina.

2005 Jul-Aug;25(5):590-596.

ONCOLOGIA OCULARE E RIABILITAZIONE VISIVA

1)Dalla Pozza G, Ghirlando A, Busato F, Midena E.

Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma: a long-term study.

Eur J Ophthalmol. 2005 Jul-Aug;15(4):446-450. 

2)Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.

Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.

Ophthalmology. 2005 Feb;112(2):208-218.

Pubblicazioni 2006

DIAGNOSI PRECOCE E VALUTAZIONE DEL DANNO MORFO-FUNZIONALE NEL GLAUCOMA

1)Parisi V, Miglior S, Manni G, Centofanti M, Bucci MG.

Clinical Ability of Pattern Electroretinograms and Visual Evoked Potentials in Detecting Visual Dysfunction in Ocular Hypertension and Glaucoma.

Ophthalmology. 2006; 113:216-28.

2)Rossetti L, Fogagnolo P, Miglior S, Centofanti M, Vetrugno M, Orzalesi N.

Learning effect of short- wavelength automated perimetry in patienst with ocular hypertension.

J of Glaucoma 2006, 15:399-404.

3)Convento E, Midena E, Dorigo MT, Maritan V, Cavarzeran F, Fregona IA.

Peripapillary fundus perimetry in eyes with glaucoma.

Br J Ophthalmol. 2006 Nov;90(11):1398-403.

4)Savini G, Bellusci C, Carbonelli M, Zanini M, Carelli V, Sadun AA, Barboni P.

Detection and quantification of retinal nerve fiber layer thickness in optic disc edema using stratus OCT.

Arch Ophthalmol. 2006 Aug;124(8):1111-7. 

5)Ricci F, Missiroli F, Parravano M. Argon.

Laser Trabeculoplasty in Triamcinolone Acetonide induced ocular hypertension refractory to maximal medical treatment.

Eur J Ophthalmol. 2006 16 (5): 756-7.

6)Barboni P, Savini G, Valentino ML, La Morgia C, Bellusci C, De Negri AM, Sadun F, Carta A, Carbonelli M, Sadun AA, Carelli V.

Leber’s Hereditary Optic Neuropathy with Childhood Onset.

Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5303-9.

7)Centofanti M, Oddone F, Chimenti S, Tanga L, Citarella L, Manni G.

First steps toward the prevention of dermatological fide effects of bimatoprost 0.03% topical therapy.

Am J Ophthal. 2006 Dec; 142 (6): 1059-60.

DIAGNOSI PRECOCE, VALUTAZIONE DEL DANNO MORFO-FUNZIONALE E TERAPIA DELLE MACULOPATIE

1)Vujosevic S, Midena E, Pilotto E, Radin PP, Chiesa L, Cavarzeran F.

Diabetic Macular Edema: Correlation between Microperimetry and Optical Coherence Tomography Findings.

Invest Ophthalmol Vis Sci. 2006 Jul;47(7):3044-3051.

2)Polito A, Napolitano MC, Bandello F, Chiodini RG.

The role of optical coherence tomography (OCT) in the diagnosis and management of retinal angiomatous proliferation (RAP) in patients with age-related macular degeneration.

Ann Acad Med Singapore. 2006 Jun;35(6):420-4.

3)Piermarocchi S, Sartore M, Bandello F, Lanzetta P, Brancato R, Garattini L, Lumbroso B, Rispoli M, Pece A, Isola V, Pulazzini A, Menchini U, Virgili G, Tedeschi M, Varano M.

Quality of Vision:A Consensus Building Initiative for a New Ophthalmologic Concept.

Eur. J Ophthalmol. 2006 Nov-Dec;16(6):851-60. 

DIAGNOSI PRECOCE E VALUTAZIONE DI FATTORI DI RISCHIO MORFOLOGICI NELLA MIOPIA ELEVATA

1)Parravano M, Oddone F, Sampalmieri M, Gazzaniga D.

Reliability of the IOL Master in axial length evaluation in silicone oil-filled eyes.

Eye, 2006, Jul 28 (on-line).

ONCOLOGIA OCULARE E RIABILITAZIONE VISIVA

1)Midena E, Bonaldi L, Parrozzani R, Tebaldi E, Boccassini B, Vujosevic S.

In vivo detection of monosomy 3 in eyes with medium-sized uveal melanoma using transscleral fine needle aspiration biopsy.

Eur J Ophthalmol. 2006 May-Jun;16(3):422-5.

2)Midena E, Brugin E, Ghirlando A, Sommavilla M, Avogaro A.

Corneal diabetic neuropathy: a confocal microscOpy study.

J Refract Surg. 2006 Nov;22(9 Suppl):S1047-52.

STUDIO DEI MECCANISMI FISIOPATOLOGICI DELLA SUPERFICIE OCULARE IN CORSO DI PATOLOGIE ALLERGICHE, AUTOIMMUNI E DEGENERATIVE. POSSIBILE RUOLO TERAPEUTICO DEL NERVE GROWTH FACTOR E DEGLI AGONISTI DEI TOLL-LIKE RECEPTORS

1)Michieletto P, Balestrazzi A, Balestrazzi A, Alegente M, Boccassini B.

Stage 4 diffuse lamellar keratitis after laser in situ keratomileusis clinical, topographical, and pachymetry resolution 5 years later.

J Cataract Refract Surg. 2006 Feb;32(2):353-6.

2)Aronni S, Cortes M, Sacchetti M, Lambiase A, Micera A, Sgrulletta R, Bonini S.

Upregulation of ICAM-1 expression in the conjunctiva of patients with chronic graft-versus-host disease.

Eur J Ophthalmol. 2006 Jan-Feb;16(1):17-23.

3)Minchiotti S, Masucci L, Serapiao Dos Santos M, Perrella E, Graffeo R, Lambiase A, Bonini S.

Conjunctival papilloma and human papillomavirus: identification of HPV types by PCR.

Eur J Ophthalmol. 2006 May-Jun;16(3):473-7.

4)Micera A, Lambiase A, Puxeddu I, Aloe L, Stampachiacchiere B, Levi-Schaffer F, Bonini S, Bonini S.

Nerve growth factor effect on human primary fibroblastic-keratocytes: possible mechanism during corneal healing.

Exp Eye Res. Exp Eye Res. 2006 Oct;83(4):747-57.

5)Sgrulletta R, Bonini S, Lambiase A, Bonini S.

Allergy and infections: long-term improvement of vernal keratoconjunctivitis following viral conjunctivitis.

Eur J Ophthalmol. 2006 May-Jun;16(3):470-3.

6)Coassin M, Lambiase A, Micera A, Tirassa P, Aloe L, Bonini S.

Nerve growth factor modulates in vitro the expression and release of TGF-beta1 by amniotic membrane.

Graefes Arch Clin Exp Ophthalmol. 2006 Apr;244(4):485-91. 

7)Sacchetti M, Lambiase A, Aronni S, Griggi T, Ribatti V, Bonini S, Bonini S.

Hyperosmolar conjunctival provocation for the evaluation of nonspecific hyperreactivity in healthy patients and patients with allergy.

J Allergy Clin Immunol. 2006 Oct;118(4):872-7. 

8)Micera A, Bonini S, Lambiase A, Lapucci G, Bonini S, Rasi G.

Conjunctival expression of thymosin-beta4 in vernal keratoconjunctivitis.

Mol Vis. 2006 Dec 20;12:1594-600.

Pubblicazioni 2007

DIAGNOSI PRECOCE, VALUTAZIONE DEL DANNO MORFO-FUNZIONALE E TERAPIA DELLE MACULOPATIE

1)Tedeschi M, Varano M, Schiano Lomoriello D, Scassa C, Parisi V.

Photodynamic therapy outcomes in a case of macular choroidal neovascularization secondary to Candida endophtalmitis.

Eur J Ophthalmol. 2007 Jan-Feb;17(1):124-7. 

2)Virgili G, Varano M, Giacomelli G, Arena M.C, Tedeschi M, Pascarella A, Catalano S, Meschini U.

Photodynamic therapy for non-subfoveal choroidal neovascularization in 100 eyes with pathologic myopia Am J Ophthalmol.

2007 Jan;143(1):77-82. 

3)Midena E, Radin PP, Convento E, Cavarzeran F.

Macular automatic fundus perimetry threshold versus standard perimetry threshold.

Eur J Ophthalmol. 2007 Jan-Feb;17(1):63-8.

4)Brugin E, Ghirlando A, Gambato C, Midena E.

Central corneal thickness: z-ring corneal confocal microscopy versus ultrasound pachymetry.

Cornea. 2007 Apr;26(3):303-7.

5)Matteucci A, Formisano G, Paradisi S, Carnovale-Scalzo G, Scorcia G, Caiazza S, Hoerauf H, Malchiodi-Albedi F.

Biocompatibility assessment of liquid artificial vitreous replacements: Relevance of in vitro studies.

Surv Ophthalmol 2007 May-Jun;52(3):289-99. 

6)Rossi T, Boccassini B, Iossa M, Mutolo MG, Lesnoni G, Mutolo PA.

Triaging and coding ophthalmic emergency – The Rome Eye Scoring System for Urgency and Emergency (RESCUE): A pilot study of 1000 eye-dedicated emergency room patients.

Eur J Ophthalmol. 2007 May-Jun;17(3):413-7.

7)Polito A, Polini G, Chiodini RG, Isola M, Soldano F, Bandello F.

Effect of posture on the diurnal variation in clinically significant diabetic macular edema.

Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3318-23.

8)Vujosevic S, Vaclavik V, Bird AC, Leung I, Dandekar S, Peto T.

Combined grading for choroidal neovascularisation: color fluorescein angiography and autofluorescience images.

Graefes Arch Clin Exp Ophthalmol. 2007 Oct;245(10):1453-1460. 

9)Parisi V, Perillo L, Tedeschi M, Scassa C, Gallinaro G, Capaldo N, Varano M.

Macular Function in Eyes With Early Age-Related Macular Degeneration With or Without Contralateral Late Age-Related Macular Degeneration.

Retina 2007 Sep;27(7):879-890.

10)Ghirlando A, Gambato C, Midena E.

LASEK and photorefractive keratectomy for myopia: clinical and confocal microscopy comparison.

J Refract Surg. 2007 Sep;23(7):694-702.

11)Virgili G, Menchini F, Dimastrogiovanni AF, Rapizzi E, Menchini U, Bandello F, Chiodini RG.

Optical coherence tomography versus stereographyc fundus phography or biomicroscopty for diagnistic diabetica macular edema: a systematic review.

Invest Ophthalmol Vis Sci. 2007 Nov;48(11):4963-73.

12)Midena E, Vujosevic S, Convento E, Manfre A, Cavarzeran F, Pilotto E.

Microperimetry and Fundus Autofluorescence in Patients with Early Age-Related Macular Degeneration.

Br J Ophthalmol.. 2007 Nov;91(11):1499-503.

13)Midena E, Gambato C, Miotto S, Cortese M, Salvi R, Ghirlando A.

Long-term effects on corneal keratocytes of mitomycin C during photorefractive keratectomy: a randomized contralateral eye confocal microscopy study.

J Refract Surg. 2007 Nov;23(9 Suppl):S1011-4.

DIAGNOSI PRECOCE E VALUTAZIONE DI FATTORI DI RISCHIO MORFOLOGICI NELLA MIOPIA ELEVATA

1)Parisi V, Coppè AM, Gallinaro G, Stirpe M.

Assessment of macular function by Focal Electroretinogram and Pattern Electroretinogram before and after epimacular membrane surgery.

Retina 2007 March; 27(3):312-20.

2)Ripandelli G, Coppè AM, Parisi V, Olzi D, Scassa C, Chiaravalloti A, Stirpe M.

Posterior vitreous detachment and retinal detachment following cataract surgery.

Ophthalmology 2007 April;114(4):692-7.

STUDIO DEI MECCANISMI FISIOPATOLOGICI DELLA SUPERFICIE OCULARE IN CORSO DI PATOLOGIE ALLERGICHE, AUTOIMMUNI E DEGENERATIVE. POSSIBILE RUOLO TERAPEUTICO DEL NERVE GROWTH FACTOR E DEGLI AGONISTI DEI TOLL-LIKE RECEPTORS

1)Sgrulletta R, Lambiase A, Micera A, Bonini S.

Corneal ulcer as an atypical presentation of ocular cicatricial pemphigoid.

Eur J Ophthalmol. 2007 Jan-Feb;17(1):121-3.

2)Lambiase A, Pagani L, Di Fausto V, Sposato V, Coassin M, Bonini S, Aloe L.

Nerve growth factor eye drop administrated on the ocular surface of rodents affects the nucleus basalis and septum: Biochemical and structural evidence.

Brain Res. 2007 Jan 5;1127:45-51. 

3)Bonini S, Mantelli F, Moretti C, Lambiase A, Bonini S, Micera A.

Itchy-Dry Eye Associated with Polycystic Ovary Syndrome.

Am J Ophthalmol. 2007 May;143(5):763-771. 

4)Mantelli F, Moretti C, Micera A, Bonini S.

Conjunctival mucin deficiency in complete androgen insensitivity syndrome (CAIS). Graefes Arch Clin Exp Ophthalmol.

2007 Jun;245(6):899-902.

5)Micera A, Lambiase A, Stampachiacchiere B, Bonini S, Bonini S, Levi-Schaffer F.

Nerve growth factor and tissue repair remodeling: trkA(NGFR) and p75(NTR), two receptors one fate.

Cytokine Growth Factor Rev. 2007 Jun-Aug;18(3-4):245-56. 

6)Micera A, Lambiase A, Stampachiacchiere B, Sgrulletta R, Normando EM, Bonini S, Bonini S.

Nerve growth factor has a modulatory role on human primary fibroblast cultures derived from vernal keratoconjunctivitis-affected conjunctiva.

Mol Vis. 2007 Jun 21;13:981-7.

7)Lambiase A, Coassin M, Sposato V, Micera A, Sacchetti M, Bonini S, Aloe L.

NGF topical application in patients with corneal ulcer does not generate circulating NGF antibodies.

Pharmacol Res. 2007 Jul;56(1):65-9. 

8)Mantelli F, Tiberi E, Micera A, Lambiase A, Visintini F, Bonini S.

MUC5AC overexpression in tear film of neonates.

Graefes Arch Clin Exp Ophthalmol. 2007 Sep;245(9):1377-81.

9)Lambiase A, Normando EM, Vitiello L, Micera A, Sacchetti M, Perrella E, Racioppi L, Bonini S, Bonini S.

Natural killer cells in vernal keratoconjunctivitis.

Mol Vis. 2007 Aug 30;13:1562-7. 

DIAGNOSI PRECOCE E VALUTAZIONE DEL DANNO MORFO-FUNZIONALE NEL GLAUCOMA

1)Oh E.C.T , Khan N, Novelli E, Khanna H, Strettoi E, Swaroop A.

Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor.

NRL Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1679-84. 

2)Di Clemente L, Coppola G, Magis D, Fumal A, De Pasqua V, Di Piero V, Schoenen J.

Interictal habituation deficit of the nociceptive blink reflex: an endophenotypic marker for presymptomatic migraine?

Brain. 2007 Mar;130(Pt 3):765-70.

3)Novelli E, Leone P, Resta V, Galli-Resta L.

A three-dimensional analysis of the development of the horizontal cell mosaic in the rat retina: Implications for the mechanisms controlling pattern formation.

Vis Neurosci. 2007 Jan-Feb;24(1):91-8.

4)Parisi V, Pierelli F, Coppola G, Restuccia R, Ferrazzoli D, Scassa C, Bianco F, Parisi L, Fattapposta F.

Reduction of optic nerve fiber layer thicknes in CADASIL.

Eur J Neurol2007, 14: 627–631.

5)Fogagnolo P, McNaught A, Centofanti M, Rossetti L, Orzalesi N.

The effects of intraocular pressure reduction on perimetric variability in glaucomatous eyes.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4557-63.

6)Coppola G, Di Clemente L, Fumal A, Magis D, De Pasqua V, Pierelli F, Schoenen J.

Inhibition of the nociceptive R2 blink reflex after supraorbital or index finger stimulation is normal in migraine without aura between attacks.

Cephalalgia 2007 Jul; 27 (7), 803–808. 

7)Resta V, Novelli E, Vozzi G, Scarpa C, Caleo1 M, Ahluwalia A, Solini A, Santini A, Parisi V, Di Virgilio F and Galli-Resta L.

Acute retinal ganglion cell injury caused by intraocular pressure spikes is mediated by endogenous extracellular ATP Eur J Neurosci.

2007 May;25(9):2741-54.

8)Curra A, Pierelli F, Coppola G, Barbanti P, Buzzi MG, Galeotti F, Serrao M, Truini A, Casali C, Pauri F, Cruccu G.

Shortened cortical silent period in facial muscles of patients with migraine.

Pain. 2007 Nov;132(1-2):124-31. 

9)Coppola G, Parisi V, Fiermonte G, Restuccia R, Pierelli F.

Asymmetrical distribution of visual evoked potentials in patients with migraine with aura during the interictal phase.

Eur. J Ophthalmol. 2007 Sep-Oct;17(5):828-35.

10)Coppola G, Ambrosiani A, Di Clemente L, Magis D, Fumal A, Gérard P, Pierelli F, Schoenen J.

Interictal abnormalities of gamma band activity in visual evoked responses in migraine: an indication of thalamocortical dysrhythmia?

Cephalalgia. 2007 Dec;27(12):1360-7.

11)Coppola G, Pierelli F, Schoenen J.

Is the cerebral cortex hyperexcitable or hyperresponsive in migraine?

Cephalalgia. 2007 Dec;27(12):1427-39. 

20)Falsini B, Ziccardi L, Stifano G, Iarossi G, Merendino E, Minnella AM, Fadda A, Balestrazzi E

Temporal Response Properties of The Macular Cone System: Effect of Normal Ageing and Age-Related Maculopathy.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4811-7.

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